| Smoothened variants explain the majority of drug resistance in basal cell carcinoma SX Atwood, KY Sarin, RJ Whitson, JR Li, G Kim, M Rezaee, MS Ally, J Kim, ... Cancer cell 27 (3), 342-353, 2015 | 441 | 2015 |
| Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition Y Tang, S Gholamin, S Schubert, MI Willardson, A Lee, P Bandopadhayay, ... Nature medicine 20 (7), 732-740, 2014 | 326 | 2014 |
| GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas SX Atwood, M Li, A Lee, JY Tang, AE Oro Nature 494 (7438), 484-488, 2013 | 280 | 2013 |
| aPKC phosphorylates Miranda to polarize fate determinants during neuroblast asymmetric cell division SX Atwood, KE Prehoda Current Biology 19 (9), 723-729, 2009 | 207 | 2009 |
| Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6–aPKC SX Atwood, C Chabu, RR Penkert, CQ Doe, KE Prehoda Journal of cell science 120 (18), 3200-3206, 2007 | 182 | 2007 |
| RAS/MAPK activation drives resistance to Smo inhibition, metastasis, and tumor evolution in Shh pathway–dependent tumors X Zhao, T Ponomaryov, KJ Ornell, P Zhou, SK Dabral, E Pak, W Li, ... Cancer research 75 (17), 3623-3635, 2015 | 159 | 2015 |
| MIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling M Bershteyn, SX Atwood, WM Woo, M Li, AE Oro Developmental cell 19 (2), 270-283, 2010 | 155 | 2010 |
| Hedgehog pathway inhibition and the race against tumor evolution SX Atwood, ALS Chang, AE Oro Journal of cell biology 199 (2), 193-197, 2012 | 148 | 2012 |
| Single cell transcriptomics of human epidermis identifies basal stem cell transition states S Wang, ML Drummond, CF Guerrero-Juarez, E Tarapore, AL MacLean, ... Nature communications 11 (1), 4239, 2020 | 135 | 2020 |
| Screening cell–cell communication in spatial transcriptomics via collective optimal transport Z Cang, Y Zhao, AA Almet, A Stabell, R Ramos, MV Plikus, SX Atwood, ... Nature methods 20 (2), 218-228, 2023 | 131 | 2023 |
| Partitioning-defective protein 6 (Par-6) activates atypical protein kinase C (aPKC) by pseudosubstrate displacement C Graybill, B Wee, SX Atwood, KE Prehoda Journal of Biological Chemistry 287 (25), 21003-21011, 2012 | 107 | 2012 |
| Effects of combined treatment with arsenic trioxide and itraconazole in patients with refractory metastatic basal cell carcinoma MS Ally, K Ransohoff, K Sarin, SX Atwood, M Rezaee, I Bailey-Healy, ... JAMA dermatology 152 (4), 452-456, 2016 | 106 | 2016 |
| Noncanonical hedgehog pathway activation through SRF–MKL1 promotes drug resistance in basal cell carcinomas RJ Whitson, A Lee, NM Urman, A Mirza, CY Yao, AS Brown, JR Li, ... Nature medicine 24 (3), 271-281, 2018 | 97 | 2018 |
| Actin polymerization controls cilia-mediated signaling ML Drummond, M Li, E Tarapore, TTL Nguyen, BJ Barouni, S Cruz, ... Journal of Cell Biology 217 (9), 3255-3266, 2018 | 87 | 2018 |
| Combined inhibition of atypical PKC and histone deacetylase 1 is cooperative in basal cell carcinoma treatment AN Mirza, MA Fry, NM Urman, SX Atwood, J Roffey, GR Ott, B Chen, ... JCI insight 2 (21), 2017 | 55 | 2017 |
| Advanced treatment for basal cell carcinomas SX Atwood, RJ Whitson, AE Oro Cold Spring Harbor perspectives in medicine 4 (7), a013581, 2014 | 54 | 2014 |
| Surgical excision after neoadjuvant therapy with vismodegib for a locally advanced basal cell carcinoma and resistant basal carcinomas in Gorlin syndrome ALS Chang, SX Atwood, DM Tartar, AE Oro JAMA dermatology 149 (5), 639-641, 2013 | 54 | 2013 |
| AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma CD Yao, D Haensel, S Gaddam, T Patel, SX Atwood, KY Sarin, ... Nature communications 11 (1), 5079, 2020 | 51 | 2020 |
| Loss of primary cilia drives switching from hedgehog to Ras/MAPK pathway in resistant basal cell carcinoma F Kuonen, NE Huskey, G Shankar, P Jaju, RJ Whitson, KE Rieger, ... Journal of Investigative Dermatology 139 (7), 1439-1448, 2019 | 49 | 2019 |
| Cell-selective bioorthogonal metabolic labeling of RNA K Nguyen, M Fazio, M Kubota, S Nainar, C Feng, X Li, SX Atwood, ... Journal of the American Chemical Society 139 (6), 2148-2151, 2017 | 47 | 2017 |
