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Christian J. Maine
Christian J. Maine
Replicate Bioscience Inc.
Verified email at pfizer.com - Homepage
Title
Cited by
Cited by
Year
Programmed death ligand-1 over-expression correlates with malignancy and contributes to immune regulation in ovarian cancer
CJ Maine, NHA Aziz, J Chatterjee, C Hayford, N Brewig, L Whilding, ...
Cancer immunology, immunotherapy 63, 215-224, 2014
1522014
PTPN22 alters the development of regulatory T cells in the thymus
CJ Maine, EE Hamilton-Williams, J Cheung, SM Stanford, N Bottini, ...
The Journal of Immunology 188 (11), 5267-5275, 2012
1292012
A miR-155–Peli1–c-Rel pathway controls the generation and function of T follicular helper cells
WH Liu, SG Kang, Z Huang, CJ Wu, HY Jin, CJ Maine, Y Liu, J Shepherd, ...
Journal of Experimental Medicine 213 (9), 1901-1919, 2016
752016
PTPN22 controls the germinal center by influencing the numbers and activity of T follicular helper cells
CJ Maine, K Marquardt, J Cheung, LA Sherman
The Journal of Immunology 192 (4), 1415-1424, 2014
722014
Clinical use of programmed cell death-1 and its ligand expression as discriminatory and predictive markers in ovarian cancer
J Chatterjee, W Dai, NHA Aziz, PY Teo, J Wahba, DL Phelps, CJ Maine, ...
Clinical Cancer Research 23 (13), 3453-3460, 2017
652017
The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development
WW Lin, Z Yi, LL Stunz, CJ Maine, LA Sherman, GA Bishop
Science signaling 8 (392), ra88-ra88, 2015
482015
CRISPR-Cas9–Mediated Modification of the NOD Mouse Genome With Ptpn22R619W Mutation Increases Autoimmune Diabetes
X Lin, S Pelletier, S Gingras, S Rigaud, CJ Maine, K Marquardt, YD Dai, ...
Diabetes 65 (8), 2134-2138, 2016
422016
PTPN22 contributes to exhaustion of T lymphocytes during chronic viral infection
CJ Maine, JR Teijaro, K Marquardt, LA Sherman
Proceedings of the National Academy of Sciences 113 (46), E7231-E7239, 2016
402016
Autoimmunity-associated LYP-W620 does not impair thymic negative selection of autoreactive T cells
DJ Wu, W Zhou, S Enouz, V Orru, SM Stanford, CJ Maine, N Rapini, ...
PLoS One 9 (2), e86677, 2014
332014
The effect of the autoimmunity-associated gene, PTPN22, on a BXSB-derived model of lupus
CJ Maine, K Marquardt, JC Scatizzi, KM Pollard, DH Kono, LA Sherman
Clinical Immunology 156 (1), 65-73, 2015
202015
Self-replicating RNAs drive protective anti-tumor T cell responses to neoantigen vaccine targets in a combinatorial approach
CJ Maine, G Richard, DS Spasova, SJ Miyake-Stoner, J Sparks, L Moise, ...
Molecular Therapy 29 (3), 1186-1198, 2021
162021
Ptpn22 and Cd2 variations are associated with altered protein expression and susceptibility to type 1 diabetes in nonobese diabetic mice
HI Fraser, S Howlett, J Clark, DB Rainbow, SM Stanford, DJ Wu, ...
The Journal of Immunology 195 (10), 4841-4852, 2015
122015
Rna replicon vaccines against hbv
JL DeHart, NS Wang, P Aliahmad, C Maine, HL Davis, C Pace
US Patent App. 17/370,337, 2022
32022
Rna replicon encoding a stabilized corona virus spike protein
J Dehart, C Maine, BS Marro, JPM Langedijk, L Rutten, R Vogels, ...
12021
Integrating context of tumor biology and vaccine design to shape multidimensional immunotherapies
NS Wang, CJ Maine
Future Drug Discovery 2 (1), FDD25, 2020
12020
Abstract PO3-26-06: A self-replicating RNA Precision Immunotherapeutic for Overcoming Resistance to Endocrine Therapy in Estrogen Receptor Positive Breast Cancer (ER+ BC)
Z Goldberg, C Maine, G Dailey, C Domingo, G Picarda, H Little, A Chou, ...
Cancer Research 84 (9_Supplement), PO3-26-06-PO3-26-06, 2024
2024
876 Self-replicating RNA therapeutics for off-the-shelf precision immunotherapy targeting acquired resistance mutations in low TMB tumors
Z Goldberg, C Maine, GP Dailey, C Domingo, G Picarda, H Little, A Chou, ...
Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023
2023
A self-replicating RNA precision medicine approach to therapeutic protein delivery of narrow therapeutic index biomolecules
Z Goldberg, C Maine, GP Dailey, C Domingo, G Picarda, H Little, A Chou, ...
Cancer Research 83 (7_Supplement), 2732-2732, 2023
2023
A self-replicating RNA precision medicine approach to overcoming resistance to endocrine therapy in ER+ BC
Z Goldberg, C Maine, GP Dailey, C Domingo, G Picarda, H Little, A Chou, ...
Cancer Research 83 (7_Supplement), 6403-6403, 2023
2023
SARS-CoV-2 Vaccines
J DeHart, C Maine, BS Marro, JPM Langedijk, L Rutten, MJG Bakkers, ...
US Patent App. 17/317,279, 2021
2021
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