John Schwabe
John Schwabe
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Cited by
Cited by
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
I Barroso, M Gurnell, VEF Crowley, M Agostini, JW Schwabe, MA Soos, ...
Nature 402 (6764), 880-883, 1999
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements
JWR Schwabe, L Chapman, JT Finch, D Rhodes
Cell 75 (3), 567-578, 1993
Zinc fingers
A Klug, JWR Schwabe
The FASEB journal 9 (8), 597-604, 1995
Solution structure of the DMA-binding domain of the oestrogen receptor
JWR Schwabe, D Neuhaus, D Rhodes
Nature 348 (6300), 458-461, 1990
Mechanism of corepressor binding and release from nuclear hormone receptors
L Nagy, HY Kao, JD Love, C Li, E Banayo, JT Gooch, V Krishna, ...
Genes & development 13 (24), 3209-3216, 1999
Structural basis for the activation of PPARγ by oxidized fatty acids
T Itoh, L Fairall, K Amin, Y Inaba, A Szanto, BL Balint, L Nagy, ...
Nature structural & molecular biology 15 (9), 924, 2008
Mechanism of the nuclear receptor molecular switch
L Nagy, JWR Schwabe
Trends in biochemical sciences 29 (6), 317-324, 2004
The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition
L Fairall, JWR Schwabe, L Chapman, JT Finch, D Rhodes
Nature 366 (6454), 483-487, 1993
Structure of HDAC3 bound to co-repressor and inositol tetraphosphate
PJ Watson, L Fairall, GM Santos, JWR Schwabe
Nature 481 (7381), 335-340, 2012
STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells
A Szanto, BL Balint, ZS Nagy, E Barta, B Dezso, A Pap, L Szeles, ...
Immunity 33 (5), 699-712, 2010
A dominant-negative peroxisome proliferator-activated receptor γ (PPARγ) mutant is a constitutive repressor and inhibits PPARγ-mediated adipogenesis
M Gurnell, JM Wentworth, M Agostini, M Adams, TN Collingwood, ...
Journal of Biological Chemistry 275 (8), 5754-5759, 2000
A mutation in the thyroid hormone receptor alpha gene
E Bochukova, N Schoenmakers, M Agostini, E Schoenmakers, ...
New England Journal of Medicine 366 (3), 243-249, 2012
St John's wort, a herbal antidepressant, activates the steroid X receptor
JM Wentworth, M Agostini, J Love, JW Schwabe, VKK Chatterjee
Journal of Endocrinology 166 (3), R11, 2000
Zinc mining for protein domains
JWR Schwabe, A Klug
Nature structural biology 1 (6), 345-349, 1994
Class I HDACs share a common mechanism of regulation by inositol phosphates
CJ Millard, PJ Watson, I Celardo, Y Gordiyenko, SM Cowley, ...
Molecular cell 51 (1), 57-67, 2013
A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death
LS Dickens, RS Boyd, R Jukes-Jones, MA Hughes, GL Robinson, ...
Molecular cell 47 (2), 291-305, 2012
Mutations in the selenocysteine insertion sequence–binding protein 2 gene lead to a multisystem selenoprotein deficiency disorder in humans
E Schoenmakers, M Agostini, C Mitchell, N Schoenmakers, L Papp, ...
The Journal of clinical investigation 120 (12), 4220-4235, 2010
International union of pharmacology. LXVI. Orphan nuclear receptors
G Benoit, A Cooney, V Giguere, H Ingraham, M Lazar, G Muscat, ...
Pharmacological reviews 58 (4), 798-836, 2006
The role of water in protein—DNA interactions
JWR Schwabe
Current opinion in structural biology 7 (1), 126-134, 1997
Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb
C Rodriguez-Esteban, JWR Schwabe, J De La Peņa, B Foys, B Eshelman, ...
Nature 386 (6623), 360-366, 1997
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