Excessive cell growth causes cytoplasm dilution and contributes to senescence GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ... cell 176 (5), 1083-1097. e18, 2019 | 463 | 2019 |
Cellular allometry of mitochondrial functionality establishes the optimal cell size TP Miettinen, M Björklund Developmental cell 39 (3), 370-382, 2016 | 154 | 2016 |
Mitochondrial function and cell size: an allometric relationship TP Miettinen, M Björklund Trends in cell biology 27 (6), 393-402, 2017 | 152 | 2017 |
Identification of transcriptional and metabolic programs related to mammalian cell size TP Miettinen, HKJ Pessa, MJ Caldez, T Fuhrer, MK Diril, U Sauer, ... Current Biology 24 (6), 598-608, 2014 | 130 | 2014 |
Cell size is a determinant of stem cell potential during aging J Lengefeld, CW Cheng, P Maretich, M Blair, H Hagen, MR McReynolds, ... Science advances 7 (46), eabk0271, 2021 | 116 | 2021 |
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK 4/6 inhibitor palbociclib TP Miettinen, J Peltier, A Härtlova, M Gierliński, VM Jansen, M Trost, ... The EMBO journal 37 (10), e98359, 2018 | 105 | 2018 |
Metabolic regulation of species-specific developmental rates M Diaz-Cuadros, TP Miettinen, OS Skinner, D Sheedy, CM Díaz-García, ... Nature 613 (7944), 550-557, 2023 | 99 | 2023 |
NQO2 is a reactive oxygen species generating off-target for acetaminophen TP Miettinen, M Björklund Molecular pharmaceutics 11 (12), 4395-4404, 2014 | 93 | 2014 |
Modified ribosome profiling reveals high abundance of ribosome protected mRNA fragments derived from 3′ untranslated regions TP Miettinen, M Björklund Nucleic acids research 43 (2), 1019-1034, 2015 | 90 | 2015 |
Noninvasive monitoring of single-cell mechanics by acoustic scattering JH Kang, TP Miettinen, L Chen, S Olcum, G Katsikis, PS Doyle, ... Nature methods 16 (3), 263-269, 2019 | 85 | 2019 |
Mevalonate pathway regulates cell size homeostasis and proteostasis through autophagy TP Miettinen, M Björklund Cell reports 13 (11), 2610-2620, 2015 | 85 | 2015 |
Nucleotide imbalance decouples cell growth from cell proliferation FF Diehl, TP Miettinen, R Elbashir, CS Nabel, AM Darnell, BT Do, ... Nature cell biology 24 (8), 1252-1264, 2022 | 81 | 2022 |
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ... Nature 588 (7838), 491-497, 2020 | 80 | 2020 |
Cell size control–a mechanism for maintaining fitness and function TP Miettinen, MJ Caldez, P Kaldis, M Björklund Bioessays 39 (9), 1700058, 2017 | 74 | 2017 |
The human cell count and size distribution IA Hatton, ED Galbraith, NSC Merleau, TP Miettinen, BMD Smith, ... Proceedings of the National Academy of Sciences 120 (39), e2303077120, 2023 | 73 | 2023 |
Mammalian cell growth dynamics in mitosis TP Miettinen, JH Kang, LF Yang, SR Manalis Elife 8, e44700, 2019 | 59 | 2019 |
Mass measurements during lymphocytic leukemia cell polyploidization decouple cell cycle-and cell size-dependent growth L Mu, JH Kang, S Olcum, KR Payer, NL Calistri, RJ Kimmerling, ... Proceedings of the National Academy of Sciences 117 (27), 15659-15665, 2020 | 54 | 2020 |
Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast PD Odermatt, TP Miettinen, J Lemière, JH Kang, E Bostan, SR Manalis, ... Elife 10, e64901, 2021 | 50 | 2021 |
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division JH Kang, G Katsikis, Z Li, KM Sapp, MA Stockslager, D Lim, ... Nature Communications 11 (1), 4983, 2020 | 32 | 2020 |
The mevalonate pathway as a metabolic requirement for autophagy–implications for growth control, proteostasis, and disease TP Miettinen, M Björklund Molecular & cellular oncology 3 (3), e1143546, 2016 | 29 | 2016 |