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Teemu P. Miettinen
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Excessive cell growth causes cytoplasm dilution and contributes to senescence
GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ...
cell 176 (5), 1083-1097. e18, 2019
4632019
Cellular allometry of mitochondrial functionality establishes the optimal cell size
TP Miettinen, M Björklund
Developmental cell 39 (3), 370-382, 2016
1542016
Mitochondrial function and cell size: an allometric relationship
TP Miettinen, M Björklund
Trends in cell biology 27 (6), 393-402, 2017
1522017
Identification of transcriptional and metabolic programs related to mammalian cell size
TP Miettinen, HKJ Pessa, MJ Caldez, T Fuhrer, MK Diril, U Sauer, ...
Current Biology 24 (6), 598-608, 2014
1302014
Cell size is a determinant of stem cell potential during aging
J Lengefeld, CW Cheng, P Maretich, M Blair, H Hagen, MR McReynolds, ...
Science advances 7 (46), eabk0271, 2021
1162021
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK 4/6 inhibitor palbociclib
TP Miettinen, J Peltier, A Härtlova, M Gierliński, VM Jansen, M Trost, ...
The EMBO journal 37 (10), e98359, 2018
1052018
Metabolic regulation of species-specific developmental rates
M Diaz-Cuadros, TP Miettinen, OS Skinner, D Sheedy, CM Díaz-García, ...
Nature 613 (7944), 550-557, 2023
992023
NQO2 is a reactive oxygen species generating off-target for acetaminophen
TP Miettinen, M Björklund
Molecular pharmaceutics 11 (12), 4395-4404, 2014
932014
Modified ribosome profiling reveals high abundance of ribosome protected mRNA fragments derived from 3′ untranslated regions
TP Miettinen, M Björklund
Nucleic acids research 43 (2), 1019-1034, 2015
902015
Noninvasive monitoring of single-cell mechanics by acoustic scattering
JH Kang, TP Miettinen, L Chen, S Olcum, G Katsikis, PS Doyle, ...
Nature methods 16 (3), 263-269, 2019
852019
Mevalonate pathway regulates cell size homeostasis and proteostasis through autophagy
TP Miettinen, M Björklund
Cell reports 13 (11), 2610-2620, 2015
852015
Nucleotide imbalance decouples cell growth from cell proliferation
FF Diehl, TP Miettinen, R Elbashir, CS Nabel, AM Darnell, BT Do, ...
Nature cell biology 24 (8), 1252-1264, 2022
812022
IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells
J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ...
Nature 588 (7838), 491-497, 2020
802020
Cell size control–a mechanism for maintaining fitness and function
TP Miettinen, MJ Caldez, P Kaldis, M Björklund
Bioessays 39 (9), 1700058, 2017
742017
The human cell count and size distribution
IA Hatton, ED Galbraith, NSC Merleau, TP Miettinen, BMD Smith, ...
Proceedings of the National Academy of Sciences 120 (39), e2303077120, 2023
732023
Mammalian cell growth dynamics in mitosis
TP Miettinen, JH Kang, LF Yang, SR Manalis
Elife 8, e44700, 2019
592019
Mass measurements during lymphocytic leukemia cell polyploidization decouple cell cycle-and cell size-dependent growth
L Mu, JH Kang, S Olcum, KR Payer, NL Calistri, RJ Kimmerling, ...
Proceedings of the National Academy of Sciences 117 (27), 15659-15665, 2020
542020
Variations of intracellular density during the cell cycle arise from tip-growth regulation in fission yeast
PD Odermatt, TP Miettinen, J Lemière, JH Kang, E Bostan, SR Manalis, ...
Elife 10, e64901, 2021
502021
Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division
JH Kang, G Katsikis, Z Li, KM Sapp, MA Stockslager, D Lim, ...
Nature Communications 11 (1), 4983, 2020
322020
The mevalonate pathway as a metabolic requirement for autophagy–implications for growth control, proteostasis, and disease
TP Miettinen, M Björklund
Molecular & cellular oncology 3 (3), e1143546, 2016
292016
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