Dominic J Smiraglia

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Christoph PlassProfessor für Epigenetik, DKFZ, HeidelbergVerified email at dkfz.de
Fred A WrightNorth Carolina State UniversityVerified email at ncsu.edu
barbara a fosterProfessor, Roswell Park Cancer InstituteVerified email at roswellpark.org
Moray J. CampbellCedars-Sinai Medical CenterVerified email at cshs.org
Christopher OakesAssistant Professor, Division of Hematology, Departments of Internal Medicine and Biomedical Informatics, The Ohio State UniversityVerified email at osumc.edu
Prashant K SinghRoswell Park Comprehensive Cancer CenterVerified email at roswellpark.org
Ralf KraheUniversity of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Christine ambrosoneRoswell Park Comprehensive Cancer CenterVerified email at roswellpark.org
Song LiuProfessor of Oncology & Vice Chair, Roswell Park Comprehensive Cancer CenterVerified email at roswellpark.org
Adam R. KarpfProfessor, Eppley Institute, University of Nebraska Medical CenterVerified email at unmc.edu
Mariola KulawiecFHCRC and UWVerified email at fhcrc.org
Sebastiano BattagliaRoswell Park Cancer Institute - Buffalo (NY)Verified email at roswellpark.org
Craig L. DoigNottingham Trent UniversityVerified email at ntu.ac.uk
Dieter WeichenhanDKFZ HeidelbergVerified email at dkfz.de
Francisco FuentesPontifical Catholic University of ChileVerified email at uc.cl
Ah-Ng Tony KongRutgers universityVerified email at pharmacy.rutgers.edu
Thomas BonfiglioProfessor Emeritus of Pathology and Laboratory Medicine, University of RochesterVerified email at urmc.rochester.edu
James L ThorneUniversity of LeedsVerified email at leeds.ac.uk
Jill L. ReiterAssistant Research Professor of Medical and Molecular Genetics, Indiana University School ofVerified email at iupui.edu
Karl KornackerEmeritus Professor of Sensory Biophysics, The Ohio State UniversityVerified email at midohio.twcbc.com

Dominic J Smiraglia

Associate Professor of Oncology, Department of Cancer Genetics, Roswell Park Cancer Institute

Verified email at roswellpark.org

Epigenomics - Cancer Genetics - Cancer Metabolism


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Aberrant CpG-island methylation has non-random and tumour-type–specific patterns JF Costello, MC Frühwald, DJ Smiraglia, LJ Rush, GP Robertson, X Gao, ... Nature genetics 24 (2), 132-138, 2000	1769	2000
SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers H Li, L Myeroff, D Smiraglia, MF Romero, TP Pretlow, L Kasturi, ... Proceedings of the National Academy of Sciences 100 (14), 8412-8417, 2003	360	2003
IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data D Wang, L Yan, Q Hu, LE Sucheston, MJ Higgins, CB Ambrosone, ... Bioinformatics 28 (5), 729-730, 2012	337	2012
Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies DJ Smiraglia, LJ Rush, MC Frühwald, Z Dai, WA Held, JF Costello, ... Human molecular genetics 10 (13), 1413-1419, 2001	310	2001
Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Developmental biology 307 (2), 368-379, 2007	270	2007
Aging results in hypermethylation of ribosomal DNA in sperm and liver of male rats CC Oakes, DJ Smiraglia, C Plass, JM Trasler, B Robaire Proceedings of the National Academy of Sciences 100 (4), 1775-1780, 2003	236	2003
A novel role for mitochondria in regulating epigenetic modifications in the nucleus D Smiraglia, M Kulawiec, GL Bistulfi, S Ghoshal, KK Singh Cancer biology & therapy 7 (8), 1182-1190, 2008	235	2008
HLTF gene silencing in human colon cancer HR Moinova, WD Chen, L Shen, D Smiraglia, J Olechnowicz, L Ravi, ... Proceedings of the National Academy of Sciences 99 (7), 4562-4567, 2002	218	2002
A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes Z Dai, WG Zhu, CD Morrison, RM Brena, DJ Smiraglia, A Raval, YZ Wu, ... Human molecular genetics 12 (7), 791-801, 2003	200	2003
Epigenetic regulation of the tumor suppressor gene TCF21 on 6q23-q24 in lung and head and neck cancer LT Smith, M Lin, RM Brena, JC Lang, DE Schuller, GA Otterson, ... Proceedings of the National Academy of Sciences 103 (4), 982-987, 2006	191	2006
Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas SR Rosario, MD Long, HC Affronti, AM Rowsam, KH Eng, DJ Smiraglia Nature communications 9 (1), 5330, 2018	186	2018
Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors DJ Smiraglia, J Szymanska, SM Kraggerud, RA Lothe, P Peltomäki, ... Oncogene 21 (24), 3909-3916, 2002	186	2002
A unique configuration of genome-wide DNA methylation patterns in the testis CC Oakes, S La Salle, DJ Smiraglia, B Robaire, JM Trasler Proceedings of the National Academy of Sciences 104 (1), 228-233, 2007	178	2007
Frequently methylated tumor suppressor genes in head and neck squamous cell carcinoma KL Bennett, M Karpenko, M Lin, R Claus, K Arab, G Dyckhoff, P Plinkert, ... Cancer research 68 (12), 4494-4499, 2008	169	2008
Methylation of the estrogen receptor-α gene promoter is selectively increased in proliferating human aortic smooth muscle cells AK Ying, HH Hassanain, CM Roos, DJ Smiraglia, JPJ Issa, RE Michler, ... Cardiovascular research 46 (1), 172-179, 2000	162	2000
Restriction landmark genome scanning JF Costello, C Plass, WK Cavenee DNA Methylation Protocols, 53-70, 2002	117	2002
The genomic impact of DNA CpG methylation on gene expression; relationships in prostate cancer MD Long, DJ Smiraglia, MJ Campbell Biomolecules 7 (1), 15, 2017	116	2017
The study of aberrant methylation in cancer via restriction landmark genomic scanning DJ Smiraglia, C Plass Oncogene 21 (35), 5414-5426, 2002	110	2002
Tissue specific DNA methylation of CpG islands in normal human adult somatic tissues distinguishes neural from non-neural tissues S Ghosh, AJ Yates, MC Frühwald, JC Miecznikowski, C Plass, ... Epigenetics 5 (6), 527-538, 2010	109	2010
Global methylation profiling of lung cancer identifies novel methylated genes Z Dai, RR Lakshmanan, WG Zhu, DJ Smiraglia, LJ Rush, MC Frühwald, ... Neoplasia 3 (4), 314-323, 2001	109	2001

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