|The Myc/Max/Mad network and the transcriptional control of cell behavior|
C Grandori, SM Cowley, LP James, RN Eisenman
Annual review of cell and developmental biology 16 (1), 653-699, 2000
|Estrogen receptors α and β form heterodimers on DNA|
SM Cowley, S Hoare, S Mosselman, MG Parker
Journal of Biological Chemistry 272 (32), 19858-19862, 1997
|Enhancer decommissioning by LSD1 during embryonic stem cell differentiation|
WA Whyte, S Bilodeau, DA Orlando, HA Hoke, GM Frampton, CT Foster, ...
Nature 482 (7384), 221-225, 2012
|Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network|
A Orian, B Van Steensel, J Delrow, HJ Bussemaker, L Li, T Sawado, ...
Genes & development 17 (9), 1101-1114, 2003
|A comparison of transcriptional activation by ERα and ERβ|
SM Cowley, MG Parker
The Journal of steroid biochemistry and molecular biology 69 (1-6), 165-175, 1999
|Histone deacetylase 1 (HDAC1), but not HDAC2, controls embryonic stem cell differentiation|
OM Dovey, CT Foster, SM Cowley
Proceedings of the National Academy of Sciences 107 (18), 8242-8247, 2010
|Class I HDACs share a common mechanism of regulation by inositol phosphates|
CJ Millard, PJ Watson, I Celardo, Y Gordiyenko, SM Cowley, ...
Molecular cell 51 (1), 57-67, 2013
|The physiological roles of histone deacetylase (HDAC) 1 and 2: complex co-stars with multiple leading parts|
RDW Kelly, SM Cowley
Biochemical Society transactions 41 (3), 741-749, 2013
|Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes|
SS Hook, A Orian, SM Cowley, RN Eisenman
Proceedings of the National Academy of Sciences 99 (21), 13425-13430, 2002
|Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability|
CT Foster, OM Dovey, L Lezina, JL Luo, TW Gant, N Barlev, A Bradley, ...
Molecular and cellular biology 30 (20), 4851-4863, 2010
|The mSin3A chromatin-modifying complex is essential for embryogenesis and T-cell development|
SM Cowley, BM Iritani, SM Mendrysa, T Xu, PF Cheng, J Yada, HD Liggitt, ...
Molecular and cellular biology 25 (16), 6990-7004, 2005
|Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice|
OM Dovey, CT Foster, N Conte, SA Edwards, JM Edwards, R Singh, ...
Blood, The Journal of the American Society of Hematology 121 (8), 1335-1344, 2013
|GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1|
R Thambyrajah, M Mazan, R Patel, V Moignard, M Stefanska, ...
Nature cell biology 18 (1), 21-32, 2016
|Solution structure of the interacting domains of the Mad–Sin3 complex: implications for recruitment of a chromatin-modifying complex|
K Brubaker, SM Cowley, K Huang, L Loo, GS Yochum, DE Ayer, ...
Cell 103 (4), 655-665, 2000
|Insights into the activation mechanism of class I HDAC complexes by inositol phosphates|
PJ Watson, CJ Millard, AM Riley, NS Robertson, LC Wright, HY Godage, ...
Nature communications 7 (1), 1-13, 2016
|Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells|
S Jamaladdin, RDW Kelly, L O’Regan, OM Dovey, GE Hodson, CJ Millard, ...
Proceedings of the National Academy of Sciences 111 (27), 9840-9845, 2014
|HBP1 and Mad1 repressors bind the Sin3 corepressor PAH2 domain with opposite helical orientations|
KA Swanson, PS Knoepfler, K Huang, RS Kang, SM Cowley, CD Laherty, ...
Nature structural & molecular biology 11 (8), 738-746, 2004
|Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach|
N Portolano, PJ Watson, L Fairall, CJ Millard, CP Milano, Y Song, ...
JoVE (Journal of Visualized Experiments), e51897, 2014
|Acetylation & Co: an expanding repertoire of histone acylations regulates chromatin and transcription|
CE Barnes, DM English, SM Cowley
Essays in biochemistry 63 (1), 97-107, 2019
|OCT4 acts as an integrator of pluripotency and signal-induced differentiation|
Z Simandi, A Horvath, LC Wright, I Cuaranta-Monroy, I De Luca, K Karolyi, ...
Molecular Cell 63 (4), 647-661, 2016