Anti-inflammatory ω-3 endocannabinoid epoxides DR McDougle, JE Watson, AA Abdeen, R Adili, MP Caputo, JE Krapf, ... Proceedings of the National Academy of Sciences 114 (30), E6034-E6043, 2017 | 183 | 2017 |
Endocannabinoids anandamide and 2-arachidonoylglycerol are substrates for human CYP2J2 epoxygenase DR McDougle, A Kambalyal, DD Meling, A Das Journal of Pharmacology and Experimental Therapeutics 351 (3), 616-627, 2014 | 65 | 2014 |
Functional studies of N‐terminally modified CYP2J2 epoxygenase in model lipid bilayers DR McDougle, A Palaria, E Magnetta, DD Meling, A Das Protein Science 22 (7), 964-979, 2013 | 54 | 2013 |
Incorporation of charged residues in the CYP2J2 FG loop disrupts CYP2J2–lipid bilayer interactions DR McDougle, JL Baylon, DD Meling, A Kambalyal, YV Grinkova, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (10), 2460-2470, 2015 | 43 | 2015 |
Granulosa cell endothelin-2 expression is fundamental for ovulatory follicle rupture JA Cacioppo, PCP Lin, PR Hannon, DR McDougle, A Gal, CM Ko Scientific reports 7 (1), 817, 2017 | 33 | 2017 |
Introduction of lipidization–cationization motifs affords systemically bioavailable neuropeptide Y and neurotensin analogs with anticonvulsant activities BR Green, KL White, DR McDougle, L Zhang, B Klein, EA Scholl, ... Journal of Peptide Science 16 (9), 486-495, 2010 | 26 | 2010 |
Analgesic properties of a peripherally acting and GalR2 receptor–preferring galanin analog in inflammatory, neuropathic, and acute pain models CS Metcalf, BD Klein, DR McDougle, L Zhang, MD Smith, G Bulaj, ... Journal of Pharmacology and Experimental Therapeutics 352 (1), 185-193, 2015 | 25 | 2015 |
Cyclooxygenase-2 catalysis and inhibition in lipid bilayer nanodiscs BJ Orlando, DR McDougle, MJ Lucido, ET Eng, LA Graham, C Schneider, ... Archives of biochemistry and biophysics 546, 33-40, 2014 | 24 | 2014 |
Preclinical evaluation of intravenous NAX 810‐2, a novel GalR2‐preferring analog, for anticonvulsant efficacy and pharmacokinetics CS Metcalf, BD Klein, DR McDougle, L Zhang, D Kaufmann, G Bulaj, ... Epilepsia 58 (2), 239-246, 2017 | 23 | 2017 |
Lipoprotein nanoplatelets: Brightly fluorescent, zwitterionic probes with rapid cellular entry SJ Lim, DR McDougle, MU Zahid, L Ma, A Das, AM Smith Journal of the American Chemical Society 138 (1), 64-67, 2016 | 20 | 2016 |
CYP2J2 epoxygenase membrane anchor plays an important role in facilitating electron transfer from CPR DD Meling, DR McDougle, A Das Journal of inorganic biochemistry 142, 47-53, 2015 | 18 | 2015 |
Incorporation of monodisperse oligoethyleneglycol amino acids into anticonvulsant analogues of galanin and neuropeptide y provides peripherally acting analgesics L Zhang, BD Klein, CS Metcalf, MD Smith, DR McDougle, HK Lee, ... Molecular Pharmaceutics 10 (2), 574-585, 2013 | 15 | 2013 |
Preclinical analgesic and safety evaluation of the GalR2-preferring analog, NAX 810-2 CS Metcalf, MD Smith, BD Klein, DR McDougle, L Zhang, G Bulaj Neurochemical research 42, 1983-1994, 2017 | 10 | 2017 |
Neuropeptide analogs, compositions, and methods for treating pain HS White, BD Klein, CS Metcalf, DR McDougle, EA Scholl, MD Smith, ... US Patent App. 13/994,675, 2013 | 3 | 2013 |
NAX 810-2, A Novel Galanin-Based Therapy for Epilepsy C Metcalf, B Klein, D McDougle, L Zhang, G Bulaj, HS White Neuropeptides 65, 150, 2017 | 1 | 2017 |
Neuropeptide analogs, compositions, and methods for treating pain HS White, BD Klein, CS Metcalf, DR Mcdougle, EA Scholl, MD Smith, ... US Patent 10,172,909, 2019 | | 2019 |
Cytochrome P450 2J2 mediated metabolism of omega-6 and omega-3 endocannabinoids DR McDougle University of Illinois at Urbana-Champaign, 2016 | | 2016 |
Neuropeptide analogs, compositions, and methods for treating pain HS White, BD Klein, CS Metcalf, DR Mcdougle, EA Scholl, MD Smith, ... | | 2012 |
2016 LIPID MAPS POSTER LIST C Cruickshank-Quinn, S Jacobson, R Bowler, I Petrache, K Kechris, ... | | |
1. Site-directed mutagenesis studies of h15-LOX-1 and their effects on inhibitor potency M Armstrong, T Horn, J Deschamps, C van Hoorebeke, C Freedman, ... | | |