Intramolecular enantioselective palladium-catalyzed Heck arylation of cyclic enamides L Ripa, A Hallberg The Journal of Organic Chemistry 62 (3), 595-602, 1997 | 128 | 1997 |
Controlled double-bond migration in palladium-catalyzed intramolecular arylation of enamidines L Ripa, A Hallberg The Journal of Organic Chemistry 61 (20), 7147-7155, 1996 | 78 | 1996 |
Explanation for main features of structure–genotoxicity relationships of aromatic amines by theoretical studies of their activation pathways in CYP1A2 I Shamovsky, L Ripa, L Borjesson, C Mee, B Nordén, P Hansen, ... Journal of the American Chemical Society 133 (40), 16168-16185, 2011 | 75 | 2011 |
Discovery of a novel oral glucocorticoid receptor modulator (AZD9567) with improved side effect profile L Ripa, K Edman, M Dearman, G Edenro, R Hendrickx, V Ullah, ... Journal of Medicinal Chemistry 61 (5), 1785-1799, 2018 | 66 | 2018 |
Synthesis of two conformationally constrained analogues of the minor tobacco alkaloid anabasine S Lindström, L Ripa, A Hallberg Organic Letters 2 (15), 2291-2293, 2000 | 62 | 2000 |
Increasing selectivity of CC chemokine receptor 8 antagonists by engineering nondesolvation related interactions with the intended and off-target binding sites I Shamovsky, C de Graaf, L Alderin, M Bengtsson, H Bladh, L Börjesson, ... Journal of medicinal chemistry 52 (23), 7706-7723, 2009 | 37 | 2009 |
Theoretical studies of chemical reactivity of metabolically activated forms of aromatic amines toward DNA I Shamovsky, L Ripa, N Blomberg, LA Eriksson, P Hansen, C Mee, ... Chemical Research in Toxicology 25 (10), 2236-2252, 2012 | 35 | 2012 |
Aryl Radical Endo Cyclization of Enamidines. Selective Preparation of Trans and Cis Fused Octahydrobenzo[f]quinolines L Ripa, A Hallberg The Journal of Organic Chemistry 63 (1), 84-91, 1998 | 32 | 1998 |
Theoretical studies of the mechanism of N-hydroxylation of primary aromatic amines by cytochrome P450 1A2: radicaloid or anionic? L Ripa, C Mee, P Sjo, I Shamovsky Chemical Research in Toxicology 27 (2), 265-278, 2014 | 21 | 2014 |
Determination of Absolute Configurations of N-Formyl-3, 3 ‘, 4, 4 ‘-tetrahydrospiro [naphthalene-1 (2 H), 2 ‘(1 ‘H)-pyridine](2) and N-Formyl-3 ‘, 4 ‘-dihydrospiro [indan-1, 2 … L Ripa, A Hallberg, J Sandström Journal of the American Chemical Society 119 (24), 5701-5705, 1997 | 20 | 1997 |
Discovery of the Oral Leukotriene C4 Synthase Inhibitor (1S,2S)-2-({5-[(5-Chloro-2,4-difluorophenyl)(2-fluoro-2-methylpropyl)amino]-3-methoxypyrazin-2-yl … M Munck af Rosenschöld, P Johannesson, A Nikitidis, C Tyrchan, ... Journal of Medicinal Chemistry 62 (17), 7769-7787, 2019 | 17 | 2019 |
Compounds B Gabos, L Ripa, K Stenvall US Patent App. 11/571,643, 2008 | 15 | 2008 |
A phenotypic screening approach using human treg cells identified regulators of forkhead Box p3 expression M Ding, J Brengdahl, M Lindqvist, U Gehrmann, E Ericson, S von Berg, ... ACS Chemical Biology 14 (3), 543-553, 2019 | 13 | 2019 |
Hydantoin derivatives for the treatment of obstructive airway diseases B Gabos, L Ripa, K Stenvall US Patent 7,648,992, 2010 | 13 | 2010 |
Fragment-based discovery of novel allosteric MEK1 binders P Di Fruscia, F Edfeldt, I Shamovsky, GW Collie, A Aagaard, L Barlind, ... ACS Medicinal Chemistry Letters 12 (2), 302-308, 2021 | 10 | 2021 |
Mechanism-based insights into removing the mutagenicity of aromatic amines by small structural alterations I Shamovsky, L Ripa, F Narjes, B Bonn, S Schiesser, I Terstiege, ... Journal of Medicinal Chemistry 64 (12), 8545-8563, 2021 | 9 | 2021 |
HDAC6 inhibitor ACY-1083 shows lung epithelial protective features in COPD J Horndahl, R Svärd, P Berntsson, C Wingren, J Li, SM Abdillahi, B Ghosh, ... PloS one 17 (10), e0266310, 2022 | 7 | 2022 |
Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling I Shamovsky, G Belfield, R Lewis, F Narjes, L Ripa, C Tyrchan, L Öberg, ... Journal of Inorganic Biochemistry 181, 28-40, 2018 | 7 | 2018 |
Hydantoin derivatives for the treatment of obstructive airway diseases B Gabos, L Ripa, K Stenvall US Patent 7,989,620, 2011 | 5 | 2011 |
Hydantoin derivatives for the treatment of obstructive airway diseases B Gabos, L Ripa, K Stenvall US Patent 7,989,620, 2011 | 5 | 2011 |