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Karen Brown
Karen Brown
Verified email at le.ac.uk
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Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13173*2021
Repeat dose study of the cancer chemopreventive agent resveratrol in healthy volunteers: safety, pharmacokinetics, and effect on the insulin-like growth factor axis
VA Brown, KR Patel, M Viskaduraki, JA Crowell, M Perloff, TD Booth, ...
Cancer research 70 (22), 9003-9011, 2010
6852010
Clinical pharmacology of resveratrol and its metabolites in colorectal cancer patients
KR Patel, VA Brown, DJL Jones, RG Britton, D Hemingway, AS Miller, ...
Cancer research 70 (19), 7392-7399, 2010
6412010
Clinical trials of resveratrol
KR Patel, E Scott, VA Brown, AJ Gescher, WP Steward, K Brown
Annals of the New York Academy of Sciences 1215 (1), 161-169, 2011
5512011
What is new for an old molecule? Systematic review and recommendations on the use of resveratrol
O Vang, N Ahmad, CA Baile, JA Baur, K Brown, A Csiszar, DK Das, ...
PloS one 6 (6), e19881, 2011
5382011
Cancer chemoprevention: a rapidly evolving field
WP Steward, K Brown
British journal of cancer 109 (1), 1-7, 2013
4452013
Phase I randomized, double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases—Safety, pharmacokinetics, and pharmacodynamics
LM Howells, DP Berry, PJ Elliott, EW Jacobson, E Hoffmann, B Hegarty, ...
Cancer prevention research 4 (9), 1419-1425, 2011
4152011
Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence
KR Patel, C Andreadi, RG Britton, E Horner-Glister, A Karmokar, S Sale, ...
Science translational medicine 5 (205), 205ra133-205ra133, 2013
2162013
Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy
MI James, C Iwuji, G Irving, A Karmokar, JA Higgins, N Griffin-Teal, ...
Cancer letters 364 (2), 135-141, 2015
1862015
Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice
H Cai, E Scott, A Kholghi, C Andreadi, A Rufini, A Karmokar, RG Britton, ...
Science translational medicine 7 (298), 298ra117-298ra117, 2015
1832015
Curcumin combined with FOLFOX chemotherapy is safe and tolerable in patients with metastatic colorectal cancer in a randomized phase IIa trial
LM Howells, COO Iwuji, GRB Irving, S Barber, H Walter, Z Sidat, ...
The Journal of nutrition 149 (7), 1133-1139, 2019
1492019
Pilot study of oral anthocyanins for colorectal cancer chemoprevention
S Thomasset, DP Berry, H Cai, K West, TH Marczylo, D Marsden, K Brown, ...
Cancer prevention research 2 (7), 625-633, 2009
1452009
Association of type 2 diabetes with cancer: a meta-analysis with bias analysis for unmeasured confounding in 151 cohorts comprising 32 million people
S Ling, K Brown, JK Miksza, L Howells, A Morrison, E Issa, T Yates, ...
Diabetes Care 43 (9), 2313-2322, 2020
1372020
Resveratrol in human cancer chemoprevention–choosing the ‘right’dose
E Scott, WP Steward, AJ Gescher, K Brown
Molecular nutrition & food research 56 (1), 7-13, 2012
1342012
Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA
DJ Boocock, K Brown, AH Gibbs, E Sanchez, KW Turteltaub, INH White
Carcinogenesis 23 (11), 1897-1902, 2002
1302002
Direct molecular targets of resveratrol: identifying key interactions to unlock complex mechanisms
RG Britton, C Kovoor, K Brown
Annals of the New York Academy of Sciences 1348 (1), 124-133, 2015
1292015
Prolonged biologically active colonic tissue levels of curcumin achieved after oral administration—a clinical pilot study including assessment of patient acceptability
GRB Irving, LM Howells, S Sale, I Kralj-Hans, WS Atkin, SK Clark, ...
Cancer prevention research 6 (2), 119-128, 2013
1292013
Pharmacokinetics and metabolism of the putative cancer chemopreventive agent cyanidin-3-glucoside in mice
TH Marczylo, D Cooke, K Brown, WP Steward, AJ Gescher
Cancer Chemotherapy and Pharmacology 64, 1261-1268, 2009
1232009
Curcumin: the potential for efficacy in gastrointestinal diseases
GRB Irving, A Karmokar, DP Berry, K Brown, WP Steward
Best practice & research Clinical gastroenterology 25 (4-5), 519-534, 2011
1192011
DNA adducts: mass spectrometry methods and future prospects
PB Farmer, K Brown, E Tompkins, VL Emms, DJL Jones, R Singh, ...
Toxicology and applied pharmacology 207 (2), 293-301, 2005
1192005
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Articles 1–20