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Michelle B Chen
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Single-cell transcriptomics of 20 mouse organs creates a Tabula Muris: The Tabula Muris Consortium
N Schaum, J Karkanias, NF Neff, AP May, SR Quake, T Wyss-Coray, ...
Nature 562 (7727), 367, 2018
938*2018
Neutrophils suppress intraluminal NK cell–mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, ...
Cancer discovery 6 (6), 630-649, 2016
4182016
The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans
The Tabula Sapiens Consortium*, RC Jones, J Karkanias, MA Krasnow, ...
Science 376 (6594), eabl4896, 2022
4132022
On-chip human microvasculature assay for visualization and quantification of tumor cell extravasation dynamics
MB Chen, JA Whisler, J Fröse, C Yu, Y Shin, RD Kamm
Nature protocols 12 (5), 865-880, 2017
3392017
A human brain vascular atlas reveals diverse mediators of Alzheimer’s risk
AC Yang, RT Vest, F Kern, DP Lee, M Agam, CA Maat, PM Losada, ...
Nature 603 (7903), 885-892, 2022
3282022
Mechanisms of tumor cell extravasation in an in vitro microvascular network platform
MB Chen, JA Whisler, JS Jeon, RD Kamm
Integrative Biology 5 (10), 1262-1271, 2013
3172013
Physiological blood–brain transport is impaired with age by a shift in transcytosis
AC Yang, MY Stevens, MB Chen, DP Lee, D Stähli, D Gate, K Contrepois, ...
Nature 583 (7816), 425-430, 2020
3022020
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
H Yousef, CJ Czupalla, D Lee, MB Chen, AN Burke, KA Zera, J Zandstra, ...
Nature medicine 25 (6), 988-1000, 2019
2942019
Generation of 3D functional microvascular networks with human mesenchymal stem cells in microfluidic systems
JS Jeon, S Bersini, JA Whisler, MB Chen, G Dubini, JL Charest, M Moretti, ...
Integrative Biology 6 (5), 555-563, 2014
2432014
Control of perfusable microvascular network morphology using a multiculture microfluidic system
JA Whisler, MB Chen, RD Kamm
Tissue engineering part C: methods 20 (7), 543-552, 2014
2412014
Microfluidics: a new tool for modeling cancer–immune interactions
A Boussommier-Calleja, R Li, MB Chen, SC Wong, RD Kamm
Trends in cancer 2 (1), 6-19, 2016
2002016
A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell–cell interactions
MB Chen, S Srigunapalan, AR Wheeler, CA Simmons
Lab on a Chip 13 (13), 2591-2598, 2013
1692013
Elucidation of the roles of tumor integrin β1 in the extravasation stage of the metastasis cascade
MB Chen, JM Lamar, R Li, RO Hynes, RD Kamm
Cancer research 76 (9), 2513-2524, 2016
1482016
Inflamed neutrophils sequestered at entrapped tumor cells via chemotactic confinement promote tumor cell extravasation
MB Chen, C Hajal, DC Benjamin, C Yu, H Azizgolshani, RO Hynes, ...
Proceedings of the National Academy of Sciences 115 (27), 7022-7027, 2018
1472018
Brain endothelial cells are exquisite sensors of age-related circulatory cues
MB Chen, AC Yang, H Yousef, D Lee, W Chen, N Schaum, B Lehallier, ...
Cell reports 30 (13), 4418-4432. e4, 2020
1452020
A chemomechanical model for nuclear morphology and stresses during cell transendothelial migration
X Cao, E Moeendarbary, P Isermann, PM Davidson, X Wang, MB Chen, ...
Biophysical journal 111 (7), 1541-1552, 2016
1282016
Neutrophils suppress intraluminal NK cell-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells. Cancer Discov. 2016; 6: 630–649. doi: 10.1158 …
A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, ...
CD-15-1157.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
95
Persistent transcriptional programmes are associated with remote memory
MB Chen, X Jiang, SR Quake, TC Südhof
Nature 587 (7834), 437-442, 2020
692020
Balance of mechanical forces drives endothelial gap formation and may facilitate cancer and immune-cell extravasation
J Escribano, MB Chen, E Moeendarbary, X Cao, V Shenoy, ...
PLoS computational biology 15 (5), e1006395, 2019
682019
Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models
AL Papa, A Jiang, N Korin, MB Chen, ET Langan, A Waterhouse, E Nash, ...
Science translational medicine 11 (479), eaau5898, 2019
622019
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