| Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth MS Samuel, JI Lopez, EJ McGhee, DR Croft, D Strachan, P Timpson, ... Cancer cell 19 (6), 776-791, 2011 | 489 | 2011 |
| ROS production and NF-κB activation triggered by RAC1 facilitate WNT-driven intestinal stem cell proliferation and colorectal cancer initiation KB Myant, P Cammareri, EJ McGhee, RA Ridgway, DJ Huels, JB Cordero, ... Cell stem cell 12 (6), 761-773, 2013 | 330 | 2013 |
| Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy BW Miller, JP Morton, M Pinese, G Saturno, NB Jamieson, E McGhee, ... EMBO molecular medicine 7 (8), 1063-1076, 2015 | 203 | 2015 |
| Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity A Kumar, M Ouyang, K Van den Dries, EJ McGhee, K Tanaka, ... Journal of Cell Biology 213 (3), 371-383, 2016 | 193 | 2016 |
| Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis C Vennin, VT Chin, SC Warren, MC Lucas, D Herrmann, A Magenau, ... Science translational medicine 9 (384), eaai8504, 2017 | 189 | 2017 |
| Hybridization of electronic states in quantum dots through photon emission K Karrai, RJ Warburton, C Schulhauser, A Högele, B Urbaszek, ... Nature 427 (6970), 135-138, 2004 | 151 | 2004 |
| Spatial Regulation of RhoA Activity during Pancreatic Cancer Cell Invasion Driven by Mutant p53RhoA Activity In Vivo P Timpson, EJ McGhee, JP Morton, A Von Kriegsheim, JP Schwarz, ... Cancer research 71 (3), 747-757, 2011 | 139 | 2011 |
| High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium CW Huo, G Chew, P Hill, D Huang, W Ingman, L Hodson, KA Brown, ... Breast Cancer Research 17 (1), 1-20, 2015 | 136 | 2015 |
| Tumor matrix stiffness promotes metastatic cancer cell interaction with the endothelium SE Reid, EJ Kay, LJ Neilson, AT Henze, J Serneels, EJ McGhee, ... The EMBO journal 36 (16), 2373-2389, 2017 | 135 | 2017 |
| CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype JB Candido, JP Morton, P Bailey, AD Campbell, SA Karim, T Jamieson, ... Cell reports 23 (5), 1448-1460, 2018 | 133 | 2018 |
| Multiplexed FRET to image multiple signaling events in live cells DM Grant, W Zhang, EJ McGhee, TD Bunney, CB Talbot, S Kumar, ... Biophysical journal 95 (10), L69-L71, 2008 | 130 | 2008 |
| Intravital FLIM-FRET Imaging Reveals Dasatinib-Induced Spatial Control of Src in Pancreatic CancerImaging Drug Targeting in Live Tumors M Nobis, EJ McGhee, JP Morton, JP Schwarz, SA Karim, J Quinn, ... Cancer research 73 (15), 4674-4686, 2013 | 118 | 2013 |
| Luminal Iron Levels Govern Intestinal Tumorigenesis after Apc Loss In Vivo S Radulescu, MJ Brookes, P Salgueiro, RA Ridgway, E McGhee, ... Cell reports 2 (2), 270-282, 2012 | 118 | 2012 |
| Organotypic collagen I assay: a malleable platform to assess cell behaviour in a 3-dimensional context P Timpson, EJ Mcghee, Z Erami, M Nobis, JA Quinn, M Edward, ... JoVE (Journal of Visualized Experiments), e3089, 2011 | 111 | 2011 |
| ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth N Rath, JP Morton, L Julian, L Helbig, S Kadir, EJ McGhee, KI Anderson, ... EMBO molecular medicine 9 (2), 198-218, 2017 | 95 | 2017 |
| High speed optically sectioned fluorescence lifetime imaging permits study of live cell signaling events DM Grant, J McGinty, EJ McGhee, TD Bunney, DM Owen, CB Talbot, ... Optics express 15 (24), 15656-15673, 2007 | 95 | 2007 |
| The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues AKE Johnsson, Y Dai, M Nobis, MJ Baker, EJ McGhee, S Walker, ... Cell reports 6 (6), 1153-1164, 2014 | 86 | 2014 |
| A RhoA-FRET biosensor mouse for intravital imaging in normal tissue homeostasis and disease contexts M Nobis, D Herrmann, SC Warren, S Kadir, W Leung, M Killen, ... Cell reports 21 (1), 274-288, 2017 | 77 | 2017 |
| Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels D Novo, N Heath, L Mitchell, G Caligiuri, A MacFarlane, D Reijmer, ... Nature communications 9 (1), 1-17, 2018 | 75 | 2018 |
| Imaging molecular dynamics in vivo–from cell biology to animal models P Timpson, EJ McGhee, KI Anderson Journal of cell science 124 (17), 2877-2890, 2011 | 75 | 2011 |
