Adult spinal motoneurones are not hyperexcitable in a mouse model of inherited amyotrophic lateral sclerosis N Delestrée, M Manuel, C Iglesias, SM Elbasiouny, CJ Heckman, ... The Journal of physiology 592 (7), 1687-1703, 2014 | 148 | 2014 |
Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS M de Lourdes Martínez-Silva, RD Imhoff-Manuel, A Sharma, CJ Heckman, ... Elife 7, e30955, 2018 | 147 | 2018 |
Alpha, beta and gamma motoneurons: functional diversity in the motor system's final pathway M Manuel, D Zytnicki Journal of integrative neuroscience 10 (03), 243-276, 2011 | 108 | 2011 |
Fast kinetics, high-frequency oscillations, and subprimary firing range in adult mouse spinal motoneurons M Manuel, C Iglesias, M Donnet, F Leroy, CJ Heckman, D Zytnicki Journal of Neuroscience 29 (36), 11246-11256, 2009 | 95 | 2009 |
MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance J Messéant, A Dobbertin, E Girard, P Delers, M Manuel, F Mangione, ... Journal of Neuroscience 35 (12), 4926-4941, 2015 | 85 | 2015 |
Mixed mode oscillations in mouse spinal motoneurons arise from a low excitability state C Iglesias, C Meunier, M Manuel, Y Timofeeva, N Delestrée, D Zytnicki Journal of Neuroscience 31 (15), 5829-5840, 2011 | 60 | 2011 |
Extra forces evoked during electrical stimulation of the muscle or its nerve are generated and modulated by a length-dependent intrinsic property of muscle in humans and cats A Frigon, CK Thompson, MD Johnson, M Manuel, TG Hornby, ... Journal of Neuroscience 31 (15), 5579-5588, 2011 | 55 | 2011 |
Synaptic restoration by cAMP/PKA drives activity-dependent neuroprotection to motoneurons in ALS M Bączyk, NO Alami, N Delestrée, C Martinot, L Tang, B Commisso, ... Journal of Experimental Medicine 217 (8), 2020 | 54 | 2020 |
Scaling of motor output, from mouse to humans M Manuel, M Chardon, V Tysseling, CJ Heckman Physiology 34 (1), 5-13, 2019 | 53 | 2019 |
Resonant or not, two amplification modes of proprioceptive inputs by persistent inward currents in spinal motoneurons M Manuel, C Meunier, M Donnet, D Zytnicki Journal of Neuroscience 27 (47), 12977-12988, 2007 | 51 | 2007 |
Liver X receptor exerts a protective effect against the oxidative stress in the peripheral nerve M Hichor, VK Sundaram, SA Eid, R Abdel-Rassoul, PX Petit, D Borderie, ... Scientific reports 8 (1), 1-13, 2018 | 44 | 2018 |
Adult mouse motor units develop almost all of their force in the subprimary range: a new all-or-none strategy for force recruitment? M Manuel, CJ Heckman Journal of Neuroscience 31 (42), 15188-15194, 2011 | 42 | 2011 |
Push–pull control of motor output MD Johnson, AS Hyngstrom, M Manuel, CJ Heckman Journal of Neuroscience 32 (13), 4592-4599, 2012 | 40 | 2012 |
Absence of UCHL 1 function leads to selective motor neuropathy B Genç, JH Jara, MC Schultz, M Manuel, MJ Stanford, M Gautam, ... Annals of clinical and translational neurology 3 (5), 331-345, 2016 | 39 | 2016 |
The afterhyperpolarization conductance exerts the same control over the gain and variability of motoneurone firing in anaesthetized cats M Manuel, C Meunier, M Donnet, D Zytnicki The Journal of physiology 576 (3), 873-886, 2006 | 38 | 2006 |
Decerebrate mouse model for studies of the spinal cord circuits CF Meehan, KA Mayr, M Manuel, ST Nakanishi, PJ Whelan Nature protocols 12 (4), 732-747, 2017 | 35 | 2017 |
Kv1. 2 Channels Promote Nonlinear Spiking Motoneurons for Powering Up Locomotion R Bos, RM Harris-Warrick, C Brocard, LE Demianenko, M Manuel, ... Cell reports 22 (12), 3315-3327, 2018 | 31 | 2018 |
How much afterhyperpolarization conductance is recruited by an action potential? A dynamic-clamp study in cat lumbar motoneurons M Manuel, C Meunier, M Donnet, D Zytnicki Journal of Neuroscience 25 (39), 8917-8923, 2005 | 29 | 2005 |
PICs in motoneurons do not scale with the size of the animal: a possible mechanism for faster speed of muscle contraction in smaller species S Huh, R Siripuram, RH Lee, VV Turkin, D O’Neill, TM Hamm, ... Journal of neurophysiology 118 (1), 93-102, 2017 | 27 | 2017 |
NMDA induces persistent inward and outward currents that cause rhythmic bursting in adult rodent motoneurons M Manuel, Y Li, SM ElBasiouny, K Murray, A Griener, CJ Heckman, ... Journal of neurophysiology 108 (11), 2991-2998, 2012 | 27 | 2012 |