|Engineering anatomically shaped human bone grafts|
WL Grayson, M Fröhlich, K Yeager, S Bhumiratana, ME Chan, ...
Proceedings of the National Academy of Sciences 107 (8), 3299-3304, 2010
|Devastation of adult stem cell pools by irradiation precedes collapse of trabecular bone quality and quantity|
DE Green, BJ Adler, ME Chan, CT Rubin
Journal of Bone and Mineral Research 27 (4), 749-759, 2012
|Vibration induced osteogenic commitment of mesenchymal stem cells is enhanced by cytoskeletal remodeling but not fluid shear|
G Uzer, S Pongkitwitoon, ME Chan, S Judex
Journal of biomechanics 46 (13), 2296-2302, 2013
|High fat diet rapidly suppresses B lymphopoiesis by disrupting the supportive capacity of the bone marrow niche|
BJ Adler, DE Green, GM Pagnotti, ME Chan, CT Rubin
PloS one 9 (3), e90639, 2014
|Bone structure and B‐cell populations, crippled by obesity, are partially rescued by brief daily exposure to low‐magnitude mechanical signals|
ME Chan, BJ Adler, DE Green, CT Rubin
The FASEB Journal 26 (12), 4855-4863, 2012
|A trabecular bone explant model of osteocyte–osteoblast co-culture for bone mechanobiology|
ME Chan, XL Lu, B Huo, AD Baik, V Chiang, RE Guldberg, HH Lu, ...
Cellular and molecular bioengineering 2 (3), 405-415, 2009
|The potential benefits and inherent risks of vibration as a non-drug therapy for the prevention and treatment of osteoporosis|
ME Chan, G Uzer, CT Rubin
Current osteoporosis reports 11 (1), 36-44, 2013
|Separating fluid shear stress from acceleration during vibrations in vitro: identification of mechanical signals modulating the cellular response|
G Uzer, SL Manske, ME Chan, FP Chiang, CT Rubin, MD Frame, S Judex
Cellular and molecular bioengineering 5 (3), 266-276, 2012
|Gap junctional communication in osteocytes is amplified by low intensity vibrations in vitro|
G Uzer, S Pongkitwitoon, C Ian, WR Thompson, J Rubin, ME Chan, ...
PloS one 9 (3), e90840, 2014
|Altered composition of bone as triggered by irradiation facilitates the rapid erosion of the matrix by both cellular and physicochemical processes|
DE Green, BJ Adler, ME Chan, JJ Lennon, AS Acerbo, LM Miller, ...
PLoS One 8 (5), e64952, 2013
|Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer|
GM Pagnotti, BJ Adler, DE Green, ME Chan, DM Frechette, KR Shroyer, ...
Bone 51 (3), 570-577, 2012
|Marrow adipogenesis and bone loss that parallels estrogen deficiency is slowed by low-intensity mechanical signals|
D Krishnamoorthy, DM Frechette, BJ Adler, DE Green, ME Chan, ...
Osteoporosis International 27 (2), 747-756, 2016
|Development of diet-induced fatty liver disease in the aging mouse is suppressed by brief daily exposure to low-magnitude mechanical signals|
YK Luu, E Ozcivici, E Capilla, B Adler, E Chan, K Shroyer, J Rubin, ...
International journal of obesity 34 (2), 401-405, 2010
|Low intensity vibration mitigates tumor progression and protects bone quantity and quality in a murine model of myeloma|
GM Pagnotti, ME Chan, BJ Adler, KR Shroyer, J Rubin, SD Bain, ...
Bone 90, 69-79, 2016
|Marrow adiposity and hematopoiesis in aging and obesity: exercise as an intervention|
VS Patel, ME Chan, J Rubin, CT Rubin
Current osteoporosis reports 16 (2), 105-115, 2018
|Incorporating refractory period in mechanical stimulation mitigates obesity‐induced adipose tissue dysfunction in adult mice|
VS Patel, ME Chan, GM Pagnotti, DM Frechette, J Rubin, CT Rubin
Obesity 25 (10), 1745-1753, 2017
|Diminished satellite cells and elevated adipogenic gene expression in muscle as caused by ovariectomy are averted by low-magnitude mechanical signals|
DM Frechette, D Krishnamoorthy, BJ Adler, ME Chan, CT Rubin
Journal of applied physiology 119 (1), 27-36, 2015
|Low‐intensity vibration increases cartilage thickness in obese mice|
T Pamon, V Bhandal, BJ Adler, M Ete Chan, CT Rubin
Journal of Orthopaedic Research® 36 (2), 751-759, 2018
|Mechanical signals protect stem cell lineage selection, preserving the bone and muscle phenotypes in obesity|
DM Frechette, D Krishnamoorthy, T Pamon, ME Chan, V Patel, CT Rubin
Annals of the New York Academy of Sciences 1409 (1), 33, 2017
|The association between sleeve gastrectomy and histopathologic changes consistent with esophagitis in a rodent model|
MS Altieri, KR Shroyer, A Pryor, GM Pagnotti, ME Chan, M Talamini, ...
Surgery for Obesity and Related Diseases 11 (6), 1289-1294, 2015