Alexander Yakunin
Alexander Yakunin
University of Toronto (Canada), Bangor University (UK)
Verified email at
Cited by
Cited by
Evolution and classification of the CRISPR–Cas systems
KS Makarova, DH Haft, R Barrangou, SJJ Brouns, E Charpentier, ...
Nature Reviews Microbiology 9 (6), 467-477, 2011
An updated evolutionary classification of CRISPR–Cas systems
KS Makarova, YI Wolf, OS Alkhnbashi, F Costa, SA Shah, SJ Saunders, ...
Nature reviews microbiology 13 (11), 722-736, 2015
Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants
KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ...
Nature Reviews Microbiology 18 (2), 67-83, 2020
Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family
E Kuznetsova, M Proudfoot, CF Gonzalez, G Brown, MV Omelchenko, ...
Journal of Biological Chemistry 281 (47), 36149-36161, 2006
A dual function of the CRISPR–Cas system in bacterial antivirus immunity and DNA repair
M Babu, N Beloglazova, R Flick, C Graham, T Skarina, B Nocek, ...
Molecular microbiology 79 (2), 484-502, 2011
In situ proteolysis for protein crystallization and structure determination
A Dong, X Xu, AM Edwards
Nature methods 4 (12), 1019-1021, 2007
Heavy metal removal by bioaccumulation using genetically engineered microorganisms
P Diep, R Mahadevan, AF Yakunin
Frontiers in bioengineering and biotechnology 6, 157, 2018
A novel family of sequence-specific endoribonucleases associated with the clustered regularly interspaced short palindromic repeats
N Beloglazova, G Brown, MD Zimmerman, M Proudfoot, KS Makarova, ...
Journal of Biological Chemistry 283 (29), 20361-20371, 2008
Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction
N Beloglazova, R Flick, A Tchigvintsev, G Brown, A Popovic, B Nocek, ...
Journal of Biological Chemistry 288 (12), 8101-8110, 2013
Enzyme genomics: Application of general enzymatic screens to discover new enzymes
E Kuznetsova, M Proudfoot, SA Sanders, J Reinking, A Savchenko, ...
FEMS microbiology reviews 29 (2), 263-279, 2005
Structure and activity of the Cas3 HD nuclease MJ0384, an effector enzyme of the CRISPR interference
N Beloglazova, P Petit, R Flick, G Brown, A Savchenko, AF Yakunin
The EMBO journal 30 (22), 4616-4627, 2011
SAMHD1 is a biomarker for cytarabine response and a therapeutic target in acute myeloid leukemia
C Schneider, T Oellerich, HM Baldauf, SM Schwarz, D Thomas, R Flick, ...
Nature medicine 23 (2), 250-255, 2017
Structural insight into the mechanism of c-di-GMP hydrolysis by EAL domain phosphodiesterases
A Tchigvintsev, X Xu, A Singer, C Chang, G Brown, M Proudfoot, H Cui, ...
Journal of molecular biology 402 (3), 524-538, 2010
Molecular basis of formaldehyde detoxification: characterization of two S-formylglutathione hydrolases from Escherichia coli, FrmB and YeiG
CF Gonzalez, M Proudfoot, G Brown, Y Korniyenko, H Mori, ...
Journal of Biological Chemistry 281 (20), 14514-14522, 2006
Polyphosphate-dependent synthesis of ATP and ADP by the family-2 polyphosphate kinases in bacteria
B Nocek, S Kochinyan, M Proudfoot, G Brown, E Evdokimova, J Osipiuk, ...
Proceedings of the National Academy of Sciences 105 (46), 17730-17735, 2008
Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica
M Kube, TN Chernikova, Y Al-Ramahi, A Beloqui, N Lopez-Cortez, ...
Nature communications 4 (1), 2156, 2013
Riboneogenesis in yeast
MF Clasquin, E Melamud, A Singer, JR Gooding, X Xu, A Dong, H Cui, ...
Cell 145 (6), 969-980, 2011
Integrating structure, bioinformatics, and enzymology to discover function: BioH, a new carboxylesterase from Escherichia coli
R Sanishvili, AF Yakunin, RA Laskowski, T Skarina, E Evdokimova, ...
Journal of Biological Chemistry 278 (28), 26039-26045, 2003
Biochemical and structural insights into enzymatic depolymerization of polylactic acid and other polyesters by microbial carboxylesterases
M Hajighasemi, BP Nocek, A Tchigvintsev, G Brown, R Flick, X Xu, H Cui, ...
Biomacromolecules 17 (6), 2027-2039, 2016
Functional and structural characterization of four glutaminases from Escherichia coli and Bacillus subtilis
G Brown, A Singer, M Proudfoot, T Skarina, Y Kim, C Chang, ...
Biochemistry 47 (21), 5724-5735, 2008
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