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Jingshu Xu
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Regional protein expression in human Alzheimer’s brain correlates with disease severity
J Xu, S Patassini, N Rustogi, I Riba-Garcia, BD Hale, AM Phillips, ...
Communications biology 2 (1), 1-15, 2019
1732019
Graded perturbations of metabolism in multiple regions of human brain in Alzheimer's disease: Snapshot of a pervasive metabolic disorder
J Xu, P Begley, SJ Church, S Patassini, KA Hollywood, M Jüllig, MA Curtis, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (6 …, 2016
1512016
Evidence for widespread, severe brain copper deficiency in Alzheimer's dementia
J Xu, SJ Church, S Patassini, P Begley, HJ Waldvogel, MA Curtis, ...
Metallomics 9 (8), 1106-1119, 2017
1012017
Elevation of brain glucose and polyol-pathway intermediates with accompanying brain-copper deficiency in patients with Alzheimer’s disease: metabolic basis for dementia
J Xu, P Begley, SJ Church, S Patassini, S McHarg, N Kureishy, ...
Scientific reports 6 (1), 1-12, 2016
872016
Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation
S Zhang, H Liu, GV Amarsingh, CCH Cheung, S Hogl, U Narayanan, ...
Cardiovascular diabetology 13 (1), 100, 2014
792014
Identification of elevated urea as a severe, ubiquitous metabolic defect in the brain of patients with Huntington's disease
S Patassini, P Begley, SJ Reid, J Xu, SJ Church, M Curtis, M Dragunow, ...
Biochemical and biophysical research communications 468 (1-2), 161-166, 2015
782015
Cerebral Vitamin B5 (D-Pantothenic Acid) Deficiency as a Potential Cause of Metabolic Perturbation and Neurodegeneration in Huntington’s Disease
S Patassini, P Begley, J Xu, SJ Church, N Kureishy, SJ Reid, ...
Metabolites 9 (6), 113, 2019
732019
Vitamin B5 (d-pantothenic acid) localizes in myelinated structures of the rat brain: Potential role for cerebral vitamin B5 stores in local myelin homeostasis
N Ismail, N Kureishy, SJ Church, M Scholefield, RD Unwin, J Xu, ...
Biochemical and biophysical research communications 522 (1), 220-225, 2020
612020
Metabolite mapping reveals severe widespread perturbation of multiple metabolic processes in Huntington's disease human brain
S Patassini, P Begley, J Xu, SJ Church, SJ Reid, EH Kim, MA Curtis, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (9 …, 2016
532016
Plasma metals as potential biomarkers in dementia: a case–control study in patients with sporadic Alzheimer’s disease
J Xu, SJ Church, S Patassini, P Begley, KAB Kellett, ERLC Vardy, ...
Biometals 31 (2), 267-276, 2018
212018
Modelling atherosclerosis by proteomics: molecular changes in the ascending aortas of cholesterol-fed rabbits
J Xu, M Jüllig, MJ Middleditch, GJS Cooper
Atherosclerosis 242 (1), 268-276, 2015
212015
Evidence that levels of nine essential metals in post-mortem human-Alzheimer’s-brain and ex-vivo rat-brain tissues are unaffected by differences in major, potentially …
M Scholefield, SJ Church, J Xu, S Kassab, NJ Gardiner, F Roncaroli, ...
Metallomics, 2020
192020
Modelling Atherosclerosis: Molecular Changes in the Ascending Aorta of Cholesterol-fed Rabbits
J Xu, M Juellig, MJ Middleditch, GJS Cooper
MOLECULAR & CELLULAR PROTEOMICS 13 (8), S33-S33, 2014
2014
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