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Leigh A Stoddart
Leigh A Stoddart
University of Nottingham
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The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 176, S21-S141, 2019
5912019
International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1,-2, and-3: pharmacology and pathophysiological functions
LA Stoddart, NJ Smith, G Milligan
Pharmacological reviews 60 (4), 405-417, 2008
3242008
The concise guide to pharmacology 2017/18: overview
SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ...
British journal of pharmacology 174, S1-S16, 2017
2652017
The concise guide to PHARMACOLOGY 2015/16: Overview
SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ...
British journal of pharmacology 172 (24), 5729-5743, 2015
2322015
Application of BRET to monitor ligand binding to GPCRs
LA Stoddart, EKM Johnstone, AJ Wheal, J Goulding, MB Robers, ...
Nature methods 12 (7), 661-663, 2015
1902015
Kinetics for Drug Discovery: an industry-driven effort to target drug residence time
DA Schuetz, WEA de Witte, YC Wong, B Knasmueller, L Richter, DB Kokh, ...
Drug Discovery Today 22 (6), 896-911, 2017
1442017
The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British journal of pharmacology 178, S27-S156, 2021
1022021
Conserved polar residues in transmembrane domains V, VI, and VII of free fatty acid receptor 2 and free fatty acid receptor 3 are required for the binding and function of short …
LA Stoddart, NJ Smith, L Jenkins, AJ Brown, G Milligan
Journal of Biological Chemistry 283 (47), 32913-32924, 2008
982008
Allosteric interactions across native adenosine‐A3 receptor homodimers: quantification using single‐cell ligand‐binding kinetics
LT May, LJ Bridge, LA Stoddart, SJ Briddon, SJ Hill
The FASEB Journal 25 (10), 3465-3476, 2011
962011
Uncovering the pharmacology of the G protein-coupled receptor GPR40: high apparent constitutive activity in guanosine 5′-O-(3-[35S] thio) triphosphate binding studies reflects …
LA Stoddart, AJ Brown, G Milligan
Molecular pharmacology 71 (4), 994-1005, 2007
902007
The Action and Mode of Binding of Thiazolidinedione Ligands at Free Fatty Acid Receptor 1*♦
NJ Smith, LA Stoddart, NM Devine, L Jenkins, G Milligan
Journal of Biological Chemistry 284 (26), 17527-17539, 2009
892009
Fluorescence‐and bioluminescence‐based approaches to study GPCR ligand binding
LA Stoddart, CW White, K Nguyen, SJ Hill, KDG Pfleger
British journal of pharmacology 173 (20), 3028-3037, 2016
862016
Fragment screening at adenosine-A3 receptors in living cells using a fluorescence-based binding assay
LA Stoddart, AJ Vernall, JL Denman, SJ Briddon, B Kellam, SJ Hill
Chemistry & biology 19 (9), 1105-1115, 2012
862012
G protein-coupled receptors for free fatty acids
G Milligan, LA Stoddart, AJ Brown
Cellular signalling 18 (9), 1360-1365, 2006
772006
Extracellular loop 2 of the free fatty acid receptor 2 mediates allosterism of a phenylacetamide ago-allosteric modulator
NJ Smith, RJ Ward, LA Stoddart, BD Hudson, E Kostenis, T Ulven, ...
Molecular pharmacology 80 (1), 163-173, 2011
742011
Probing the pharmacology of G protein-coupled receptors with fluorescent ligands
LA Stoddart, LE Kilpatrick, SJ Briddon, SJ Hill
Neuropharmacology 98, 48-57, 2015
722015
NanoBRET approaches to study ligand binding to GPCRs and RTKs
LA Stoddart, LE Kilpatrick, SJ Hill
Trends in pharmacological sciences 39 (2), 136-147, 2018
622018
Agonism and allosterism: the pharmacology of the free fatty acid receptors FFA2 and FFA3
G Milligan, LA Stoddart, NJ Smith
British journal of pharmacology 158 (1), 146-153, 2009
602009
Binding kinetics of ligands acting at GPCRs
DA Sykes, LA Stoddart, LE Kilpatrick, SJ Hill
Molecular and cellular endocrinology 485, 9-19, 2019
552019
Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surface
C Pou, CM la Cour, LA Stoddart, MJ Millan, G Milligan
Journal of Biological Chemistry 287 (12), 8864-8878, 2012
542012
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Articles 1–20