| Fatty acid carbon is essential for dNTP synthesis in endothelial cells S Schoors, U Bruning, R Missiaen, KCS Queiroz, G Borgers, I Elia, ... Nature 520 (7546), 192-197, 2015 | 541 | 2015 |
| Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells I Elia, D Broekaert, S Christen, R Boon, E Radaelli, MF Orth, C Verfaillie, ... Nature communications 8 (1), 15267, 2017 | 336 | 2017 |
| Metabolites and the tumour microenvironment: from cellular mechanisms to systemic metabolism I Elia, MC Haigis Nature metabolism 3 (1), 21-32, 2021 | 290 | 2021 |
| The mTORC1/S6K1 pathway regulates glutamine metabolism through the eIF4B-dependent control of c-Myc translation A Csibi, G Lee, SO Yoon, H Tong, D Ilter, I Elia, SM Fendt, TM Roberts, ... Current biology 24 (19), 2274-2280, 2014 | 271 | 2014 |
| Breast cancer cells rely on environmental pyruvate to shape the metastatic niche I Elia, M Rossi, S Stegen, D Broekaert, G Doglioni, M van Gorsel, R Boon, ... Nature 568 (7750), 117-121, 2019 | 245 | 2019 |
| Pyruvate kinase isoform expression alters nucleotide synthesis to impact cell proliferation SY Lunt, V Muralidhar, AM Hosios, WJ Israelsen, DY Gui, L Newhouse, ... Molecular cell 57 (1), 95-107, 2015 | 245 | 2015 |
| Breast cancer-derived lung metastases show increased pyruvate carboxylase-dependent anaplerosis S Christen, D Lorendeau, R Schmieder, D Broekaert, K Metzger, K Veys, ... Cell reports 17 (3), 837-848, 2016 | 227 | 2016 |
| Quiescent endothelial cells upregulate fatty acid β-oxidation for vasculoprotection via redox homeostasis J Kalucka, L Bierhansl, NV Conchinha, R Missiaen, I Elia, U Brüning, ... Cell metabolism 28 (6), 881-894. e13, 2018 | 210 | 2018 |
| Metabolic hallmarks of metastasis formation I Elia, G Doglioni, SM Fendt Trends in cell biology 28 (8), 673-684, 2018 | 203 | 2018 |
| Age-induced accumulation of methylmalonic acid promotes tumour progression AP Gomes, D Ilter, V Low, JE Endress, J Fernández-García, ... Nature 585 (7824), 283-287, 2020 | 143 | 2020 |
| Organ-specific cancer metabolism and its potential for therapy I Elia, R Schmieder, S Christen, SM Fendt Metabolic Control, 321-353, 2016 | 132 | 2016 |
| Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines R Boon, M Kumar, T Tricot, I Elia, L Ordovas, F Jacobs, J One, J De Smedt, ... Nature communications 11 (1), 1393, 2020 | 101 | 2020 |
| Oncometabolite d-2HG alters T cell metabolism to impair CD8+ T cell function G Notarangelo, JB Spinelli, EM Perez, GJ Baker, K Kurmi, I Elia, ... Science 377 (6614), 1519-1529, 2022 | 98 | 2022 |
| Tumor cells dictate anti-tumor immune responses by altering pyruvate utilization and succinate signaling in CD8+ T cells I Elia, JH Rowe, S Johnson, S Joshi, G Notarangelo, K Kurmi, S Weiss, ... Cell metabolism 34 (8), 1137-1150. e6, 2022 | 88 | 2022 |
| Altered propionate metabolism contributes to tumour progression and aggressiveness AP Gomes, D Ilter, V Low, S Drapela, T Schild, E Mullarky, J Han, I Elia, ... Nature metabolism 4 (4), 435-443, 2022 | 39 | 2022 |
| In vivo cancer metabolism is defined by the nutrient microenvironment I Elia, SM Fendt Translational Cancer Research 5 (Suppl 6), 2016 | 39 | 2016 |
| Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis MP Rossmann, K Hoi, V Chan, BJ Abraham, S Yang, J Mullahoo, ... Science 372 (6543), 716-721, 2021 | 28 | 2021 |
| 13C Tracer Analysis and Metabolomics in 3D Cultured Cancer Cells M van Gorsel, I Elia, SM Fendt Metabolic Signaling: Methods and Protocols, 53-66, 2019 | 23 | 2019 |
| Myogenic induction of adult and pluripotent stem cells using recombinant proteins I Perini, I Elia, AL Nigro, F Ronzoni, E Berardi, H Grosemans, S Fukada, ... Biochemical and biophysical research communications 464 (3), 755-761, 2015 | 14 | 2015 |
| Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade JH Rowe, I Elia, O Shahid, EF Gaudiano, NE Sifnugel, S Johnson, ... Cancer discovery 13 (12), 2566-2583, 2023 | 5 | 2023 |
