| Bile acids control inflammation and metabolic disorder through inhibition of NLRP3 inflammasome C Guo, S Xie, Z Chi, J Zhang, Y Liu, L Zhang, M Zheng, X Zhang, D Xia, ... Immunity 45 (4), 802-816, 2016 | 657 | 2016 |
| MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2 L Ding, Y Xu, W Zhang, Y Deng, M Si, Y Du, H Yao, X Liu, Y Ke, J Si, ... Cell research 20 (7), 784-793, 2010 | 414 | 2010 |
| African origin of modern humans in East Asia: a tale of 12,000 Y chromosomes Y Ke, B Su, X Song, D Lu, L Chen, H Li, C Qi, S Marzuki, R Deka, ... science 292 (5519), 1151-1153, 2001 | 359 | 2001 |
| PTEN regulation by Akt–EGR1–ARF–PTEN axis J Yu, SS Zhang, K Saito, S Williams, Y Arimura, Y Ma, Y Ke, V Baron, ... The EMBO journal 28 (1), 21-33, 2009 | 172 | 2009 |
| Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality Y Ke, EE Zhang, K Hagihara, D Wu, Y Pang, R Klein, T Curran, B Ranscht, ... Molecular and cellular biology 27 (19), 6706-6717, 2007 | 154 | 2007 |
| Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis BO Tao, W Jin, J Xu, Z Liang, J Yao, Y Zhang, K Wang, H Cheng, X Zhang, ... The Journal of Immunology 193 (6), 2801-2811, 2014 | 110 | 2014 |
| Conditional deletion of Shp2 tyrosine phosphatase in thymocytes suppresses both pre-TCR and TCR signals TV Nguyen, Y Ke, EE Zhang, GS Feng The Journal of Immunology 177 (9), 5990-5996, 2006 | 102 | 2006 |
| Role of Gab2 in mammary tumorigenesis and metastasis Y Ke, D Wu, F Princen, T Nguyen, Y Pang, J Lesperance, WJ Muller, ... Oncogene 26 (34), 4951-4960, 2007 | 95 | 2007 |
| Multiple origins of Tibetan Y chromosomes Y Qian, B Qian, B Su, J Yu, Y Ke, Z Chu, L Shi, D Lu, J Chu, L Jin Human genetics 106, 453-454, 2000 | 92 | 2000 |
| Conditional deletion of Shp2 in the mammary gland leads to impaired lobulo-alveolar outgrowth and attenuated Stat5 activation Y Ke, J Lesperance, EE Zhang, EA Bard-Chapeau, RG Oshima, ... Journal of biological chemistry 281 (45), 34374-34380, 2006 | 80 | 2006 |
| Y 染色体单倍型在中国汉族人群中的多态性分布与中国人群的起源及迁移 柯越海， 宿兵， 肖君华， 陈华， 黄薇， 陈竺， 褚嘉佑， 谈家祯， 金力， 卢大儒 中国科学 (C 辑) 30 (6), 614-620, 2000 | 76 | 2000 |
| Phosphatase Shp2 exacerbates intestinal inflammation by disrupting macrophage responsiveness to interleukin-10 P Xiao, H Zhang, Y Zhang, M Zheng, R Liu, Y Zhao, X Zhang, H Cheng, ... Journal of Experimental Medicine 216 (2), 337-349, 2019 | 71 | 2019 |
| Shp2 Plays an Important Role in Acute Cigarette Smoke-Mediated Lung Inflammation F Li, J Shen, H Shen, X Zhang, R Cao, Y Zhang, Q Qui, X Lin, Y Xie, ... The Journal of Immunology 189 (6), 3159-3167, 2012 | 66 | 2012 |
| Class III PI3K positively regulates platelet activation and thrombosis via PI (3) P-directed function of NADPH oxidase Y Liu, M Hu, D Luo, M Yue, S Wang, X Chen, Y Zhou, Y Wang, Y Cai, ... Arteriosclerosis, thrombosis, and vascular biology 37 (11), 2075-2086, 2017 | 64 | 2017 |
| A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase D Wu, Y Pang, Y Ke, J Yu, Z He, L Tautz, T Mustelin, S Ding, Z Huang, ... PLoS One 4 (3), e4914, 2009 | 64 | 2009 |
| Selective Sequestration of STAT1 in the Cytoplasm via Phosphorylated SHP-2 Ameliorates Murine Experimental Colitis X Wu, W Guo, L Wu, Y Gu, L Gu, S Xu, X Wu, Y Shen, Y Ke, R Tan, Y Sun, ... The Journal of Immunology, 2012 | 62 | 2012 |
| Oxidative stress-induced FABP5 S-glutathionylation protects against acute lung injury by suppressing inflammation in macrophages Y Guo, Y Liu, S Zhao, W Xu, Y Li, P Zhao, D Wang, H Cheng, Y Ke, ... Nature Communications 12 (1), 7094, 2021 | 59 | 2021 |
| Endothelial deletion of SHP2 suppresses tumor angiogenesis and promotes vascular normalization Z Xu, C Guo, Q Ye, Y Shi, Y Sun, J Zhang, J Huang, Y Huang, C Zeng, ... Nature communications 12 (1), 6310, 2021 | 58 | 2021 |
| A dynamic real-time method for monitoring epithelial barrier function in vitro M Sun, H Fu, H Cheng, Q Cao, Y Zhao, X Mou, X Zhang, X Liu, Y Ke Analytical biochemistry 425 (2), 96-103, 2012 | 58 | 2012 |
| Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1 G Fu, Q Xu, Y Qiu, X Jin, T Xu, S Dong, J Wang, Y Ke, H Hu, X Cao, ... Journal of Experimental Medicine 214 (5), 1453-1469, 2017 | 57 | 2017 |
Hongqiang ChengZhejiang University School of Medicine Department of PathologyVerified email at zju.edu.cn
