| mTORC1 targets the translational repressor 4E-BP2, but not S6 kinase 1/2, to regulate neural stem cell self-renewal in vivo NW Hartman, TV Lin, L Zhang, GE Paquelet, DM Feliciano, A Bordey Cell reports 5 (2), 433-444, 2013 | 145 | 2013 |
| Immune checkpoint modulators in cancer immunotherapy: recent advances and emerging concepts Y Wang, H Zhang, C Liu, Z Wang, W Wu, N Zhang, L Zhang, J Hu, P Luo, ... Journal of Hematology & Oncology 15 (1), 111, 2022 | 118 | 2022 |
| Minimally invasive surgery is superior to conventional craniotomy in patients with spontaneous supratentorial intracerebral hemorrhage: a systematic review and meta-analysis Z Xia, X Wu, J Li, Z Liu, F Chen, L Zhang, H Zhang, X Wan, Q Cheng World neurosurgery 115, 266-273, 2018 | 70 | 2018 |
| Circadian clock genes promote glioma progression by affecting tumour immune infiltration and tumour cell proliferation Z Wang, G Su, Z Dai, M Meng, H Zhang, F Fan, Z Liu, L Zhang, N Weygant, ... Cell proliferation 54 (3), e12988, 2021 | 57 | 2021 |
| Reconstruction of Large-scale Defects with a Novel Hybrid Scaffold Made from Poly(L-lactic acid)/Nanohydroxyapatite/Alendronate-loaded Chitosan Microsphere: in vitro and … H Wu, P Lei, G Liu, Y Shrike Zhang, J Yang, L Zhang, J Xie, W Niu, H Liu, ... Scientific reports 7 (1), 359, 2017 | 52 | 2017 |
| MEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR L Zhang, CM Bartley, X Gong, LS Hsieh, TV Lin, DM Feliciano, A Bordey Neuron 84 (1), 78-91, 2014 | 48 | 2014 |
| Rheb activation in subventricular zone progenitors leads to heterotopia, ectopic neuronal differentiation, and rapamycin-sensitive olfactory micronodules and dendrite … CA Lafourcade, TV Lin, DM Feliciano, L Zhang, LS Hsieh, A Bordey Journal of Neuroscience 33 (6), 2419-2431, 2013 | 48 | 2013 |
| Copresentation of tumor antigens and costimulatory molecules via biomimetic nanoparticles for effective cancer immunotherapy J Ma, F Liu, WC Sheu, Z Meng, Y Xie, H Xu, M Li, AT Chen, J Liu, Y Bao, ... Nano Letters 20 (6), 4084-4094, 2020 | 42 | 2020 |
| Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo X Gong, L Zhang, T Huang, TV Lin, L Miyares, J Wen, L Hsieh, A Bordey Human molecular genetics 24 (20), 5746-5758, 2015 | 42 | 2015 |
| Genomic analysis of primary and recurrent gliomas reveals clinical outcome related molecular features L Zhang, Z Liu, J Li, T Huang, Y Wang, L Chang, W Zheng, Y Ma, F Chen, ... Scientific reports 9 (1), 16058, 2019 | 36 | 2019 |
| Ectopic HCN4 expression drives mTOR-dependent epilepsy in mice LS Hsieh, JH Wen, LH Nguyen, L Zhang, SA Getz, J Torres-Reveron, ... Science translational medicine 12 (570), eabc1492, 2020 | 27 | 2020 |
| Filamin A inhibition reduces seizure activity in a mouse model of focal cortical malformations L Zhang, T Huang, S Teaw, LH Nguyen, LS Hsieh, X Gong, LH Burns, ... Science Translational Medicine 12 (531), eaay0289, 2020 | 27 | 2020 |
| Identification of a potential exosomal biomarker in spinocerebellar ataxia Type 3/Machado–Joseph disease X Hou, X Gong, L Zhang, T Li, H Yuan, Y Xie, Y Peng, R Qiu, K Xia, ... Epigenomics 11 (9), 1037-1056, 2019 | 24 | 2019 |
| Oncogenic role of MicroRNA-30b-5p in glioblastoma through targeting proline-rich transmembrane protein 2 Z Li, J Guo, Y Ma, L Zhang, Z Lin Oncology research 26 (2), 219, 2018 | 22 | 2018 |
| Combination therapy of RY10-4 with the γ-secretase inhibitor DAPT shows promise in treating HER2-amplified breast cancer F Su, S Zhu, J Ruan, Y Muftuoglu, L Zhang, Q Yuan Oncotarget 7 (4), 4142, 2016 | 18 | 2016 |
| JMJD8 is an M2 macrophage biomarker, and it associates with DNA damage repair to facilitate stemness maintenance, chemoresistance, and immunosuppression in pan-cancer X Liang, H Zhang, Z Wang, X Zhang, Z Dai, J Zhang, P Luo, L Zhang, J Hu, ... Frontiers in immunology 13, 875786, 2022 | 16 | 2022 |
| miRNA-182 regulated MTSS1 inhibits proliferation and invasion in Glioma Cells Z Li, L Zhang, Z Liu, T Huang, Y Wang, Y Ma, X Fang, Y He, Y Zhou, ... Journal of Cancer 11 (19), 5840, 2020 | 16 | 2020 |
| Hypervascularization in mTOR‐dependent focal and global cortical malformations displays differential rapamycin sensitivity L Zhang, T Huang, S Teaw, A Bordey Epilepsia 60 (6), 1255-1265, 2019 | 16 | 2019 |
| Molecular insight into pentraxin-3: Update advances in innate immunity, inflammation, tissue remodeling, diseases, and drug role H Zhang, R Wang, Z Wang, W Wu, N Zhang, L Zhang, J Hu, P Luo, ... Biomedicine & Pharmacotherapy 156, 113783, 2022 | 13 | 2022 |
| Expression of 4E-BP1 in juvenile mice alleviates mTOR-induced neuronal dysfunction and epilepsy LH Nguyen, Y Xu, T Mahadeo, L Zhang, TV Lin, HA Born, AE Anderson, ... Brain 145 (4), 1310-1325, 2022 | 13 | 2022 |
