Dominique Helmlinger
Dominique Helmlinger
Group Leader, CRBM, University of Montpellier
Verified email at - Homepage
TitleCited byYear
Ataxin-7 is a subunit of GCN5 histone acetyltransferase-containing complexes
D Helmlinger, S Hardy, S Sasorith, F Klein, F Robert, C Weber, L Miguet, ...
Human molecular genetics 13 (12), 1257-1265, 2004
Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction
D Helmlinger, S Hardy, G Abou-Sleymane, A Eberlin, AB Bowman, ...
PLoS biology 4 (3), e67, 2006
SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types
G Yvert, KS Lindenberg, D Devys, D Helmlinger, GB Landwehrmeyer, ...
Human Molecular Genetics 10 (16), 1679-1692, 2001
Polyglutamine expansion induces a protein-damaging stress connecting heat shock protein 70 to the JNK pathway
K Merienne, D Helmlinger, GR Perkin, D Devys, Y Trottier
Journal of Biological Chemistry 278 (19), 16957-16967, 2003
Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice
D Helmlinger, G Yvert, S Picaud, K Merienne, J Sahel, JL Mandel, ...
Human molecular genetics 11 (26), 3351-3359, 2002
The S. pombe SAGA complex controls the switch from proliferation to sexual differentiation through the opposing roles of its subunits Gcn5 and Spt8
D Helmlinger, S Marguerat, J Villén, SP Gygi, J Bähler, F Winston
Genes & development 22 (22), 3184-3195, 2008
Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program
G Abou-Sleymane, F Chalmel, D Helmlinger, A Lardenois, C Thibault, ...
Human molecular genetics 15 (5), 691-703, 2006
Transcriptional alterations and chromatin remodeling in polyglutamine diseases
D Helmlinger, L Tora, D Devys
TRENDS in Genetics 22 (10), 562-570, 2006
Retinal cell type expression specificity of HIV‐1‐derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter
AP Bemelmans, S Bonnel, L Houhou, N Dufour, E Nandrot, D Helmlinger, ...
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2005
Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model
D Helmlinger, G Abou-Sleymane, G Yvert, S Rousseau, C Weber, ...
Journal of Neuroscience 24 (8), 1881-1887, 2004
Tra1 has specific regulatory roles, rather than global functions, within the SAGA co‐activator complex
D Helmlinger, S Marguerat, J Villén, DL Swaney, SP Gygi, J Bähler, ...
The EMBO journal 30 (14), 2843-2852, 2011
Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice
D Helmlinger, J Bonnet, JL Mandel, Y Trottier, D Devys
Journal of Biological Chemistry 279 (53), 55969-55977, 2004
Sharing the SAGA
D Helmlinger, L Tora
Trends in biochemical sciences 42 (11), 850-861, 2017
Both normal and polyglutamine-expanded ataxin-7 are components of TFTC-type GCN5 histone acetyltransferase-containing complexes
D Helmlinger, S Hardy, A Eberlin, D Devys, L Tora
Biochemical Society Symposia 73, 155-163, 2006
Long-term engraftment of systemically transplanted, gene-modified bone marrow-derived cells in the adult mouse retina
C Boettcher, E Ulbricht, D Helmlinger, AF Mack, A Reichenbach, ...
British Journal of Ophthalmology 92 (2), 272-275, 2008
TORC1 and TORC2 converge to regulate the SAGA co‐activator in response to nutrient availability
T Laboucarié, D Detilleux, RA Rodriguez‐Mias, C Faux, Y Romeo, ...
EMBO reports 18 (12), 2197-2218, 2017
The Hos2 histone deacetylase controls Ustilago maydis virulence through direct regulation of mating-type genes
A Elías-Villalobos, A Fernández-Álvarez, I Moreno-Sánchez, ...
PLoS pathogens 11 (8), e1005134, 2015
New insights into the SAGA complex from studies of the Tra1 subunit in budding and fission yeast
D Helmlinger
Transcription 3 (1), 13-18, 2012
Histone deacetylases: revealing the molecular base of dimorphism in pathogenic fungi
A Elías-Villalobos, D Helmlinger, JI Ibeas
Microbial Cell 2 (12), 491, 2015
Rôle d’une désorganisation de la chromatine dans la neurodégénérescence due à une expansion de polyglutamine dans l’ataxine-7
D Helmlinger, L Tora, D Devys
médecine/sciences 22 (8-9), 700-702, 2006
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