|The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise|
J Jensen, PI Rustad, AJ Kolnes, YC Lai
Frontiers in physiology 2, 112, 2011
|Insulin action and signalling in fat and muscle from dexamethasone-treated rats|
J Burén, YC Lai, M Lundgren, JW Eriksson, J Jensen
Archives of biochemistry and biophysics 474 (1), 91-101, 2008
|Phosphoproteomic screening identifies Rab GTP ases as novel downstream targets of PINK 1|
YC Lai, C Kondapalli, R Lehneck, JB Procter, BD Dill, HI Woodroof, ...
The EMBO journal 34 (22), 2840-2861, 2015
|Regulation of muscle glycogen synthase phosphorylation and kinetic properties by insulin, exercise, adrenaline and role in insulin resistance|
J Jensen, YC Lai
Archives of physiology and biochemistry 115 (1), 13-21, 2009
|AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B|
M Johanns, YC Lai, MF Hsu, R Jacobs, D Vertommen, J Van Sande, ...
Nature communications 7 (1), 1-12, 2016
|Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation|
KC Pao, M Stanley, C Han, YC Lai, P Murphy, K Balk, NT Wood, O Corti, ...
Nature chemical biology 12 (5), 324-331, 2016
|A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK …|
YC Lai, S Kviklyte, D Vertommen, L Lantier, M Foretz, B Viollet, S Hallén, ...
Biochemical Journal 460 (3), 363-375, 2014
|Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle|
Y Liu, YC Lai, EV Hill, D Tyteca, S Carpentier, A Ingvaldsen, ...
Biochemical Journal 455 (2), 195-206, 2013
|GSK-3β regulation in skeletal muscles by adrenaline and insulin: Evidence that PKA and PKB regulate different pools of GSK-3|
J Jensen, EO Brennesvik, YC Lai, PR Shepherd
Cellular signalling 19 (1), 204-210, 2007
|Glycogen content and contraction regulate glycogen synthase phosphorylation and affinity for UDP-glucose in rat skeletal muscles|
YC Lai, JT Stuenĉs, CH Kuo, J Jensen
American Journal of Physiology-Endocrinology and Metabolism 293 (6), E1622-E1629, 2007
|Additive effect of contraction and insulin on glucose uptake and glycogen synthase in muscle with different glycogen contents|
YC Lai, E Zarrinpashneh, J Jensen
Journal of applied physiology 108 (5), 1106-1115, 2010
|A novel PKB/Akt inhibitor, MK-2206, effectively inhibits insulin-stimulated glucose metabolism and protein synthesis in isolated rat skeletal muscle|
YC Lai, Y Liu, R Jacobs, MH Rider
Biochemical Journal 447 (1), 137-147, 2012
|Nicotinamide riboside augments the aged human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures|
YS Elhassan, K Kluckova, RS Fletcher, MS Schmidt, A Garten, CL Doig, ...
Cell reports 28 (7), 1717-1728. e6, 2019
|Mammalian target of rapamycin-independent S6K1 and 4E-BP1 phosphorylation during contraction in rat skeletal muscle|
Y Liu, D Vertommen, MH Rider, YC Lai
Cellular signalling 25 (9), 1877-1886, 2013
|β‐Adrenoceptor stimulation potentiates insulin‐stimulated PKB phosphorylation in rat cardiomyocytes via cAMP and PKA|
JT Stuenĉs, A Bolling, A Ingvaldsen, C Rommundstad, E Sudar, FC Lin, ...
British journal of pharmacology 160 (1), 116-129, 2010
|Kinetin riboside and its ProTides activate the Parkinson’s disease associated PTEN-induced putative kinase 1 (PINK1) independent of mitochondrial depolarization|
L Osgerby, YC Lai, PJ Thornton, J Amalfitano, CS Le Duff, I Jabeen, ...
Journal of medicinal chemistry 60 (8), 3518-3524, 2017
|Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle|
J Jensen, T Ruge, YC Lai, MK Svensson, JW Eriksson
Metabolism 60 (2), 215-226, 2011
|Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle|
L Bultot, TE Jensen, YC Lai, ALB Madsen, C Collodet, S Kviklyte, M Deak, ...
American Journal of Physiology-Endocrinology and Metabolism 311 (4), E706-E719, 2016
|Effects of pharmacological AMP deaminase inhibition and Ampd1 deletion on nucleotide levels and AMPK activation in contracting skeletal muscle|
C Plaideau, YC Lai, S Kviklyte, N Zanou, L Löfgren, H Andersén, ...
Chemistry & biology 21 (11), 1497-1510, 2014
|The role of dehydroepiandrosterone levels on physiologic acclimatization to chronic mountaineering activity|
WC Lee, SM Chen, MC Wu, CW Hou, YC Lai, YH Laio, CH Lin, CH Kuo
High altitude medicine & biology 7 (3), 228-236, 2006