Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2175 | 2019 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 174 | 2021 |
Targeted disruption of the extracellular polymeric network of Pseudomonas aeruginosa biofilms by alginate oligosaccharides LC Powell, MF Pritchard, EL Ferguson, KA Powell, SU Patel, PD Rye, ... npj Biofilms and Microbiomes 4 (1), 13, 2018 | 147 | 2018 |
Association of genetic liability to psychotic experiences with neuropsychotic disorders and traits SE Legge, HJ Jones, KM Kendall, AF Pardiñas, G Menzies, ... JAMA psychiatry 76 (12), 1256-1265, 2019 | 133 | 2019 |
A new class of safe oligosaccharide polymer therapy to modify the mucus barrier of chronic respiratory disease MF Pritchard, LC Powell, GE Menzies, PD Lewis, K Hawkins, C Wright, ... Molecular Pharmaceutics 13 (3), 863-872, 2016 | 83 | 2016 |
Fourier transform infrared for noninvasive optical diagnosis of oral, oropharyngeal, and laryngeal cancer GE Menzies, HR Fox, C Marnane, L Pope, V Prabhu, S Winter, AV Derrick, ... Translational Research 163 (1), 19-26, 2014 | 52 | 2014 |
Age-dependent effect of APOE and polygenic component on Alzheimer's disease E Bellou, E Baker, G Leonenko, M Bracher-Smith, P Daunt, G Menzies, ... Neurobiology of aging 93, 69-77, 2020 | 39 | 2020 |
Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, AC Naj, A Boland, ... BioRxiv, 294629, 2018 | 35 | 2018 |
Exome sequencing of individuals with Huntington’s disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset B McAllister, J Donaldson, CS Binda, S Powell, U Chughtai, G Edwards, ... Nature neuroscience 25 (4), 446-457, 2022 | 33 | 2022 |
Polygenic risk for schizophrenia and subcortical brain anatomy in the UK Biobank cohort S Grama, I Willcocks, JJ Hubert, AF Pardiñas, SE Legge, M Bracher-Smith, ... Translational psychiatry 10 (1), 309, 2020 | 30 | 2020 |
Genetic liability to schizophrenia is negatively associated with educational attainment in UK Biobank V Escott-Price, M Bracher-Smith, G Menzies, J Walters, G Kirov, MJ Owen, ... Molecular psychiatry 25 (4), 703-705, 2020 | 28 | 2020 |
Human gestation-associated tissues express functional cytosolic nucleic acid sensing pattern recognition receptors AH Bryant, GE Menzies, LM Scott, S Spencer-Harty, LB Davies, RA Smith, ... Clinical & Experimental Immunology 189 (1), 36-46, 2017 | 24 | 2017 |
Base damage, local sequence context and TP53 mutation hotspots: a molecular dynamics study of benzo[a]pyrene induced DNA distortion and mutability GE Menzies, SH Reed, A Brancale, PD Lewis Nucleic acids research 43 (19), 9133-9146, 2015 | 24 | 2015 |
PIP2 depletion and altered endocytosis caused by expression of Alzheimer's disease‐protective variant PLCγ2 R522 E Maguire, GE Menzies, T Phillips, M Sasner, HM Williams, MA Czubala, ... The EMBO journal 40 (17), e105603, 2021 | 20 | 2021 |
Association of genetic liability for psychiatric disorders with accelerometer-assessed physical activity in the UK Biobank CA Dennison, SE Legge, M Bracher-Smith, G Menzies, V Escott-Price, ... PLoS One 16 (3), e0249189, 2021 | 19 | 2021 |
Machine learning for prediction of schizophrenia using genetic and demographic factors in the UK biobank M Bracher-Smith, E Rees, G Menzies, JTR Walters, MC O'Donovan, ... Schizophrenia research 246, 156-164, 2022 | 15 | 2022 |
Vibrational spectra, principal components analysis and the horseshoe effect PD Lewis, GE Menzies Vibrational Spectroscopy 81, 62-67, 2015 | 13 | 2015 |
Topical, immunomodulatory epoxy-tiglianes induce biofilm disruption and healing in acute and chronic skin wounds LC Powell, JK Cullen, GM Boyle, T De Ridder, PY Yap, W Xue, CJ Pierce, ... Science translational medicine 14 (662), eabn3758, 2022 | 11 | 2022 |
Benefits and challenges of rare genetic variation in Alzheimer’s disease D Grozeva, S Saad, GE Menzies, R Sims Current Genetic Medicine Reports 7, 53-62, 2019 | 11 | 2019 |
Characterizing the original anti‐C5 function‐blocking antibody, BB5. 1, for species specificity, mode of action and interactions with C5 WM Zelek, GE Menzies, A Brancale, B Stockinger, BP Morgan Immunology 161 (2), 103-113, 2020 | 10 | 2020 |