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David Finlay
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T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
S Sauer, L Bruno, A Hertweck, D Finlay, M Leleu, M Spivakov, ZA Knight, ...
Proceedings of the National Academy of Sciences 105 (22), 7797-7802, 2008
8942008
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
DK Finlay, E Rosenzweig, LV Sinclair, C Feijoo-Carnero, JL Hukelmann, ...
Journal of Experimental Medicine 209 (13), 2441-2453, 2012
5132012
Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking
LV Sinclair, D Finlay, C Feijoo, GH Cornish, A Gray, A Ager, K Okkenhaug, ...
Nature immunology 9 (5), 513-521, 2008
4172008
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
S Viel, A Marçais, FSF Guimaraes, R Loftus, J Rabilloud, M Grau, ...
Science signaling 9 (415), ra19-ra19, 2016
3992016
Immunometabolism: cellular metabolism turns immune regulator
RM Loftus, DK Finlay
Journal of Biological Chemistry 291 (1), 1-10, 2016
3312016
mTORC1-dependent metabolic reprogramming is a prerequisite for NK cell effector function
RP Donnelly, RM Loftus, SE Keating, KT Liou, CA Biron, CM Gardiner, ...
The Journal of Immunology 193 (9), 4477-4484, 2014
3122014
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ...
Nature immunology 19 (12), 1330-1340, 2018
2812018
Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism
AN Macintyre, D Finlay, G Preston, LV Sinclair, CM Waugh, P Tamas, ...
Immunity 34 (2), 224-236, 2011
2532011
Metabolism, migration and memory in cytotoxic T cells
D Finlay, DA Cantrell
Nature Reviews Immunology 11 (2), 109-117, 2011
2492011
AMPK α1: A glucose sensor that controls CD 8 T‐cell memory
J Rolf, M Zarrouk, DK Finlay, M Foretz, B Viollet, DA Cantrell
European journal of immunology 43 (4), 889-896, 2013
2282013
Srebp-controlled glucose metabolism is essential for NK cell functional responses
N Assmann, KL O'Brien, RP Donnelly, L Dyck, V Zaiatz-Bittencourt, ...
Nature immunology 18 (11), 1197-1206, 2017
1922017
Metabolic reprogramming supports IFN-γ production by CD56bright NK cells
SE Keating, V Zaiatz-Bittencourt, RM Loftus, C Keane, K Brennan, ...
The Journal of Immunology 196 (6), 2552-2560, 2016
1902016
Immunometabolism and natural killer cell responses
KL O’Brien, DK Finlay
Nature Reviews Immunology 19 (5), 282-290, 2019
1872019
Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
RM Loftus, N Assmann, N Kedia-Mehta, KL O’Brien, A Garcia, C Gillespie, ...
Nature communications 9 (1), 1-15, 2018
1602018
Notch‐induced T cell development requires phosphoinositide‐dependent kinase 1
AP Kelly, DK Finlay, HJ Hinton, RG Clarke, E Fiorini, F Radtke, ...
The EMBO journal 26 (14), 3441-3450, 2007
1352007
Glucose, glycolysis and lymphocyte responses
RP Donnelly, DK Finlay
Molecular immunology 68 (2), 513-519, 2015
1342015
Competition for nutrients and its role in controlling immune responses
N Kedia-Mehta, DK Finlay
Nature Communications 10 (1), 1-8, 2019
1222019
Phosphoinositide 3‐kinase and the mammalian target of rapamycin pathways control T cell migration
D Finlay, D Cantrell
Annals of the New York Academy of Sciences 1183 (1), 149-157, 2010
1002010
Canonical TGF-β signaling pathway represses human NK cell metabolism
V Zaiatz-Bittencourt, DK Finlay, CM Gardiner
The Journal of Immunology 200 (12), 3934-3941, 2018
972018
Glucose represses dendritic cell-induced T cell responses
SJ Lawless, N Kedia-Mehta, JF Walls, R McGarrigle, O Convery, ...
Nature communications 8 (1), 1-14, 2017
932017
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