| A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia B Button, LH Cai, C Ehre, M Kesimer, DB Hill, JK Sheehan, RC Boucher, ... Science 337 (6097), 937-941, 2012 | 855 | 2012 |
| Clinical significance of symptoms in smokers with preserved pulmonary function PG Woodruff, RG Barr, E Bleecker, SA Christenson, D Couper, JL Curtis, ... New England Journal of Medicine 374 (19), 1811-1821, 2016 | 699 | 2016 |
| Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense M Kesimer, M Scull, B Brighton, G DeMaria, K Burns, W O'Neal, ... The FASEB Journal 23 (6), 1858, 2009 | 397 | 2009 |
| Design of the subpopulations and intermediate outcomes in COPD study (SPIROMICS) D Couper, LM LaVange, ML Han, RG Barr, E Bleecker, EA Hoffman, ... Thorax 69 (5), 492-495, 2014 | 368 | 2014 |
| E-cigarette use causes a unique innate immune response in the lung, involving increased neutrophilic activation and altered mucin secretion B Reidel, G Radicioni, PW Clapp, AA Ford, S Abdelwahab, ME Rebuli, ... American journal of respiratory and critical care medicine 197 (4), 492-501, 2018 | 363 | 2018 |
| Cystic fibrosis airway secretions exhibit mucin hyperconcentration and increased osmotic pressure AG Henderson, C Ehre, B Button, LH Abdullah, LH Cai, MW Leigh, ... The Journal of clinical investigation 124 (7), 3047-3060, 2014 | 343 | 2014 |
| Airway mucin concentration as a marker of chronic bronchitis M Kesimer, AA Ford, A Ceppe, G Radicioni, R Cao, CW Davis, ... New England Journal of Medicine 377 (10), 911-922, 2017 | 340 | 2017 |
| Nanoparticle analysis of circulating cell-derived vesicles in ovarian cancer patients C Gercel-Taylor, S Atay, RH Tullis, M Kesimer, DD Taylor Analytical biochemistry 428 (1), 44-53, 2012 | 264 | 2012 |
| Localization of secretory mucins MUC5AC and MUC5B in normal/healthy human airways K Okuda, G Chen, DB Subramani, M Wolf, RC Gilmore, T Kato, ... American journal of respiratory and critical care medicine 199 (6), 715-727, 2019 | 233 | 2019 |
| At the root: defining and halting progression of early chronic obstructive pulmonary disease FJ Martinez, MLK Han, JP Allinson, RG Barr, RC Boucher, PMA Calverley, ... American journal of respiratory and critical care medicine 197 (12), 1540-1551, 2018 | 227 | 2018 |
| Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airways M Kesimer, C Ehre, KA Burns, CW Davis, JK Sheehan, RJ Pickles Mucosal immunology 6 (2), 379-392, 2013 | 217 | 2013 |
| Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways? M Kesimer, S Kirkham, RJ Pickles, AG Henderson, NE Alexis, G DeMaria, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 296 (1 …, 2009 | 210 | 2009 |
| Reduced three-dimensional motility in dehydrated airway mucus prevents neutrophil capture and killing bacteria on airway epithelial surfaces H Matsui, MW Verghese, M Kesimer, UE Schwab, SH Randell, ... The journal of immunology 175 (2), 1090-1099, 2005 | 182 | 2005 |
| Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis CR Esther Jr, MS Muhlebach, C Ehre, DB Hill, MC Wolfgang, M Kesimer, ... Science translational medicine 11 (486), eaav3488, 2019 | 180 | 2019 |
| Chronic exposure to beta-blockers attenuates inflammation and mucin content in a murine asthma model LP Nguyen, O Omoluabi, S Parra, JM Frieske, C Clement, ... American journal of respiratory cell and molecular biology 38 (3), 256-262, 2008 | 180 | 2008 |
| Morphologic and proteomic characterization of exosomes released by cultured extravillous trophoblast cells S Atay, C Gercel-Taylor, M Kesimer, DD Taylor Experimental cell research 317 (8), 1192-1202, 2011 | 172 | 2011 |
| The relationship of mucus concentration (hydration) to mucus osmotic pressure and transport in chronic bronchitis WH Anderson, RD Coakley, B Button, AG Henderson, KL Zeman, ... American journal of respiratory and critical care medicine 192 (2), 182-190, 2015 | 161 | 2015 |
| Unpacking a gel-forming mucin: a view of MUC5B organization after granular release M Kesimer, AM Makhov, JD Griffith, P Verdugo, JK Sheehan American Journal of Physiology-Lung Cellular and Molecular Physiology 298 (1 …, 2010 | 153 | 2010 |
| Physical characterization and profiling of airway epithelial derived exosomes using light scattering M Kesimer, R Gupta Methods 87, 59-63, 2015 | 107 | 2015 |
| IL-1β dominates the promucin secretory cytokine profile in cystic fibrosis G Chen, L Sun, T Kato, K Okuda, MB Martino, A Abzhanova, JM Lin, ... The Journal of clinical investigation 129 (10), 4433-4450, 2019 | 106 | 2019 |
Richard BoucherProfessor of Medicine, University of NC at Chapel HillVerified email at med.unc.edu
