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Rui M C Portela
Rui M C Portela
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Cited by
Cited by
Year
Synthetic core promoters as universal parts for fine-tuning expression in different yeast species
RMC Portela, T Vogl, C Kniely, JE Fischer, R Oliveira, A Glieder
ACS synthetic biology 6 (3), 471-484, 2017
1072017
When is an in silico representation a digital twin? A biopharmaceutical industry approach to the digital twin concept
RMC Portela, C Varsakelis, A Richelle, N Giannelos, J Pence, S Dessoy, ...
Digital Twins: Tools and Concepts for Smart Biomanufacturing, 35-55, 2021
402021
Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis
RMC Portela, T Vogl, K Ebner, R Oliveira, A Glieder
Biotechnology Journal 13 (3), 1700340, 2018
392018
Enabling PAT in insect cell bioprocesses: In situ monitoring of recombinant adeno‐associated virus production by fluorescence spectroscopy
DAM Pais, RMC Portela, MJT Carrondo, IA Isidro, PM Alves
Biotechnology and Bioengineering 116 (11), 2803-2814, 2019
282019
A roadmap to AI-driven in silico process development: bioprocessing 4.0 in practice
M von Stosch, RMC Portela, C Varsakelis
Current Opinion in Chemical Engineering 33, 100692, 2021
232021
Towards in silico process modeling for vaccines
AG Cardillo, MM Castellanos, B Desailly, S Dessoy, M Mariti, ...
Trends in biotechnology 39 (11), 1120-1130, 2021
182021
Towards a widespread adoption of metabolic modeling tools in biopharmaceutical industry: a process systems biology engineering perspective
A Richelle, B David, D Demaegd, M Dewerchin, R Kinet, A Morreale, ...
NPJ systems biology and applications 6 (1), 6, 2020
182020
Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination
AR Ferreira, JML Dias, AP Teixeira, N Carinhas, RMC Portela, IA Isidro, ...
BMC Systems Biology 5, 1-13, 2011
182011
Hybrid metabolic flux analysis and recombinant protein prediction in Pichia pastoris X-33 cultures expressing a single-chain antibody fragment
IA Isidro, RM Portela, JJ Clemente, AE Cunha, R Oliveira
Bioprocess and biosystems engineering 39, 1351-1363, 2016
162016
Analysis of transformed upstream bioprocess data provides insights into biological system variation
A Richelle, BW Lee, RMC Portela, J Raley, M von Stosch
Biotechnology Journal 15 (10), 2000113, 2020
122020
Hybrid modeling of microbial exopolysaccharide (EPS) production: The case of Enterobacter A47
R Marques, M von Stosch, RMC Portela, CAV Torres, S Antunes, F Freitas, ...
Journal of biotechnology 246, 61-70, 2017
112017
Hybrid semiparametric systems for quantitative sequence-activity modeling of synthetic biological parts
RMC Portela, M von Stosch, R Oliveira
Synthetic Biology 3 (1), ysy010, 2018
102018
Hybrid model structures for knowledge integration
M von Stosch, RMC Portela, R Oliveira
Hybrid Modeling in Process Industries, 13-35, 2018
72018
Time Integrated Flux Analysis: Exploiting the Concentration Measurements Directly for Cost-Effective Metabolic Network Flux Analysis
RMC Portela, A Richelle, P Dumas, M von Stosch
Microorganisms 7 (12), 620, 2019
12019
Hybrid ann-mechanistic models for general chemical and biochemical processes
C Azevedo, R Lee, RMC Portela, S Von, R Oliveira
Artificial Neural Networks in Chemical Engineering, 229-256, 2017
12017
Enabling PAT in insect cell bioprocesses: A monitoring toolbox for rAAV production
IA Isidro, DAM Pais, R Portela, A Kryzhanska, P Galrão, MJT Carrondo, ...
INTEGRATED CONTINUOUS BIOMANUFACTURING V, 2022
2022
Monitoring the production of AAV vectors in insect cells by fluorescence spectroscopy
DA Marques Pais, IA Isidro, PM Alves, R Portela
CELL CULTURE ENGINEERING XVI, 2018
2018
Cell functional enviromics of Pichia pastoris cells
RMC Portela, R Oliveira
FEBS JOURNAL 284, 234-234, 2017
2017
Synthetic core promoters and 5′ untranslated regions (UTRs) as universal parts for fine-tuning expression in different yeast species
RMC Portela, T Vogl, R Oliveira, A Glieder
17th European Congress on Biotechnology (New Biotechnology Journal), S183, 2016
2016
Towards the rational design of standard biological parts for Synthetic Biology: applications to microbial systems
RMC Portela
Faculdade de Ciencias e Tecnologia - Universidade Nova de Lisboa, 2016
2016
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