Synthetic core promoters as universal parts for fine-tuning expression in different yeast species RMC Portela, T Vogl, C Kniely, JE Fischer, R Oliveira, A Glieder ACS synthetic biology 6 (3), 471-484, 2017 | 107 | 2017 |
When is an in silico representation a digital twin? A biopharmaceutical industry approach to the digital twin concept RMC Portela, C Varsakelis, A Richelle, N Giannelos, J Pence, S Dessoy, ... Digital Twins: Tools and Concepts for Smart Biomanufacturing, 35-55, 2021 | 40 | 2021 |
Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis RMC Portela, T Vogl, K Ebner, R Oliveira, A Glieder Biotechnology Journal 13 (3), 1700340, 2018 | 39 | 2018 |
Enabling PAT in insect cell bioprocesses: In situ monitoring of recombinant adeno‐associated virus production by fluorescence spectroscopy DAM Pais, RMC Portela, MJT Carrondo, IA Isidro, PM Alves Biotechnology and Bioengineering 116 (11), 2803-2814, 2019 | 28 | 2019 |
A roadmap to AI-driven in silico process development: bioprocessing 4.0 in practice M von Stosch, RMC Portela, C Varsakelis Current Opinion in Chemical Engineering 33, 100692, 2021 | 23 | 2021 |
Towards in silico process modeling for vaccines AG Cardillo, MM Castellanos, B Desailly, S Dessoy, M Mariti, ... Trends in biotechnology 39 (11), 1120-1130, 2021 | 18 | 2021 |
Towards a widespread adoption of metabolic modeling tools in biopharmaceutical industry: a process systems biology engineering perspective A Richelle, B David, D Demaegd, M Dewerchin, R Kinet, A Morreale, ... NPJ systems biology and applications 6 (1), 6, 2020 | 18 | 2020 |
Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination AR Ferreira, JML Dias, AP Teixeira, N Carinhas, RMC Portela, IA Isidro, ... BMC Systems Biology 5, 1-13, 2011 | 18 | 2011 |
Hybrid metabolic flux analysis and recombinant protein prediction in Pichia pastoris X-33 cultures expressing a single-chain antibody fragment IA Isidro, RM Portela, JJ Clemente, AE Cunha, R Oliveira Bioprocess and biosystems engineering 39, 1351-1363, 2016 | 16 | 2016 |
Analysis of transformed upstream bioprocess data provides insights into biological system variation A Richelle, BW Lee, RMC Portela, J Raley, M von Stosch Biotechnology Journal 15 (10), 2000113, 2020 | 12 | 2020 |
Hybrid modeling of microbial exopolysaccharide (EPS) production: The case of Enterobacter A47 R Marques, M von Stosch, RMC Portela, CAV Torres, S Antunes, F Freitas, ... Journal of biotechnology 246, 61-70, 2017 | 11 | 2017 |
Hybrid semiparametric systems for quantitative sequence-activity modeling of synthetic biological parts RMC Portela, M von Stosch, R Oliveira Synthetic Biology 3 (1), ysy010, 2018 | 10 | 2018 |
Hybrid model structures for knowledge integration M von Stosch, RMC Portela, R Oliveira Hybrid Modeling in Process Industries, 13-35, 2018 | 7 | 2018 |
Time Integrated Flux Analysis: Exploiting the Concentration Measurements Directly for Cost-Effective Metabolic Network Flux Analysis RMC Portela, A Richelle, P Dumas, M von Stosch Microorganisms 7 (12), 620, 2019 | 1 | 2019 |
Hybrid ann-mechanistic models for general chemical and biochemical processes C Azevedo, R Lee, RMC Portela, S Von, R Oliveira Artificial Neural Networks in Chemical Engineering, 229-256, 2017 | 1 | 2017 |
Enabling PAT in insect cell bioprocesses: A monitoring toolbox for rAAV production IA Isidro, DAM Pais, R Portela, A Kryzhanska, P Galrão, MJT Carrondo, ... INTEGRATED CONTINUOUS BIOMANUFACTURING V, 2022 | | 2022 |
Monitoring the production of AAV vectors in insect cells by fluorescence spectroscopy DA Marques Pais, IA Isidro, PM Alves, R Portela CELL CULTURE ENGINEERING XVI, 2018 | | 2018 |
Cell functional enviromics of Pichia pastoris cells RMC Portela, R Oliveira FEBS JOURNAL 284, 234-234, 2017 | | 2017 |
Synthetic core promoters and 5′ untranslated regions (UTRs) as universal parts for fine-tuning expression in different yeast species RMC Portela, T Vogl, R Oliveira, A Glieder 17th European Congress on Biotechnology (New Biotechnology Journal), S183, 2016 | | 2016 |
Towards the rational design of standard biological parts for Synthetic Biology: applications to microbial systems RMC Portela Faculdade de Ciencias e Tecnologia - Universidade Nova de Lisboa, 2016 | | 2016 |