| Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains AM Oudelaar, JOJ Davies, LLP Hanssen, JM Telenius, R Schwessinger, ... Nature genetics 50 (12), 1744-1751, 2018 | 177 | 2018 |
| A blood atlas of COVID-19 defines hallmarks of disease severity and specificity DJ Ahern, Z Ai, M Ainsworth, C Allan, A Allcock, B Angus, MA Ansari, ... Cell 185 (5), 916-938. e58, 2022 | 158 | 2022 |
| Identification of LZTFL1 as a candidate effector gene at a COVID-19 risk locus DJ Downes, AR Cross, P Hua, N Roberts, R Schwessinger, AJ Cutler, ... Nature genetics 53 (11), 1606-1615, 2021 | 135 | 2021 |
| DeepC: predicting 3D genome folding using megabase-scale transfer learning R Schwessinger, M Gosden, D Downes, RC Brown, AM Oudelaar, ... Nature methods 17 (11), 1118-1124, 2020 | 118 | 2020 |
| Defining genome architecture at base-pair resolution P Hua, M Badat, LLP Hanssen, LD Hentges, N Crump, DJ Downes, ... Nature 595 (7865), 125-129, 2021 | 111 | 2021 |
| Sasquatch: predicting the impact of regulatory SNPs on transcription factor binding from cell-and tissue-specific DNase footprints R Schwessinger, MC Suciu, SJ McGowan, J Telenius, S Taylor, DR Higgs, ... Genome research 27 (10), 1730-1742, 2017 | 50 | 2017 |
| Targeting fibroblast growth factor receptor 1 for treatment of soft-tissue sarcoma P Chudasama, M Renner, M Straub, SS Mughal, B Hutter, Z Kosaloglu, ... Clinical cancer research 23 (4), 962-973, 2017 | 38 | 2017 |
| Enhancers predominantly regulate gene expression during differentiation via transcription initiation MSC Larke, R Schwessinger, T Nojima, J Telenius, RA Beagrie, ... Molecular cell 81 (5), 983-997. e7, 2021 | 37 | 2021 |
| High-resolution targeted 3C interrogation of cis-regulatory element organization at genome-wide scale DJ Downes, RA Beagrie, ME Gosden, J Telenius, SJ Carpenter, ... Nature Communications 12 (1), 531, 2021 | 31 | 2021 |
| Whole-genome sequencing of chronic lymphocytic leukemia identifies subgroups with distinct biological and clinical features P Robbe, KE Ridout, DV Vavoulis, H Dréau, B Kinnersley, N Denny, ... Nature genetics 54 (11), 1675-1689, 2022 | 30 | 2022 |
| The chromatin remodeller ATRX facilitates diverse nuclear processes, in a stochastic manner, in both heterochromatin and euchromatin J Truch, DJ Downes, C Scott, ER Gür, JM Telenius, E Repapi, ... Nature Communications 13 (1), 3485, 2022 | 19 | 2022 |
| CaptureCompendium: a comprehensive toolkit for 3C analysis JM Telenius, DJ Downes, M Sergeant, AM Oudelaar, S McGowan, J Kerry, ... Biorxiv, 2020.02. 17.952572, 2020 | 13 | 2020 |
| An integrated platform to systematically identify causal variants and genes for polygenic human traits DJ Downes, R Schwessinger, SJ Hill, L Nussbaum, C Scott, ME Gosden, ... BioRxiv, 813618, 2019 | 13 | 2019 |
| Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19 CP Kotanidis, C Xie, D Alexander, JCL Rodrigues, K Burnham, A Mentzer, ... The Lancet Digital Health 4 (10), e705-e716, 2022 | 12 | 2022 |
| Dynamic Runx1 chromatin boundaries affect gene expression in hematopoietic development DDG Owens, G Anselmi, AM Oudelaar, DJ Downes, A Cavallo, ... Nature communications 13 (1), 773, 2022 | 12 | 2022 |
| Recapitulation of erythropoiesis in congenital dyserythropoietic anemia type I (CDA-I) identifies defects in differentiation and nucleolar abnormalities C Scott, DJ Downes, JM Brown, RA Beagrie, AA Olijnik, M Gosden, ... Haematologica 106 (11), 2960, 2021 | 11 | 2021 |
| DeepC: Predicting chromatin interactions using megabase scaled deep neural networks and transfer learning R Schwessinger, M Gosden, D Downes, R Brown, J Telenius, YW Teh, ... bioRxiv, 724005, 2019 | 9 | 2019 |
| Direct correction of haemoglobin E β-thalassaemia using base editors M Badat, A Ejaz, P Hua, S Rice, W Zhang, LD Hentges, CA Fisher, ... Nature Communications 14 (1), 2238, 2023 | 7 | 2023 |
| COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium, Gill DR, Hyde SC, Knight JC, Todd JA, Sansom SN, Issa F, Davies JOJ, Hughes JR. 2021. Identification of LZTFL1 as a … DJ Downes, AR Cross, P Hua, N Roberts, R Schwessinger, AJ Cutler, ... Nat Genet 53, 1606-1615, 0 | 5 | |
| Structural and non-coding variants increase the diagnostic yield of clinical whole genome sequencing for rare diseases AT Pagnamenta, C Camps, E Giacopuzzi, JM Taylor, M Hashim, ... Genome medicine 15 (1), 94, 2023 | 4 | 2023 |
