| Biophysical mechanism of T-cell receptor triggering in a reconstituted system JR James, RD Vale Nature 487 (7405), 64-69, 2012 | 383 | 2012 |
| A rigorous experimental framework for detecting protein oligomerization using bioluminescence resonance energy transfer JR James, MI Oliveira, AM Carmo, A Iaboni, SJ Davis Nature methods 3 (12), 1001-1006, 2006 | 365 | 2006 |
| Membrane-proximal epitope facilitates efficient T cell synapse formation by anti-FcRH5/CD3 and is a requirement for myeloma cell killing J Li, NJ Stagg, J Johnston, MJ Harris, SA Menzies, D DiCara, V Clark, ... Cancer cell 31 (3), 383-395, 2017 | 245 | 2017 |
| Crystal structure of a soluble CD28-Fab complex EJ Evans, RM Esnouf, R Manso-Sancho, RJC Gilbert, JR James, C Yu, ... Nature immunology 6 (3), 271-279, 2005 | 217 | 2005 |
| Selective, rapid and optically switchable regulation of protein function in live mammalian cells YH Tsai, S Essig, JR James, K Lang, JW Chin Nature chemistry 7 (7), 554-561, 2015 | 159 | 2015 |
| MARK4 regulates NLRP3 positioning and inflammasome activation through a microtubule-dependent mechanism X Li, S Thome, X Ma, M Amrute-Nayak, A Finigan, L Kitt, L Masters, ... Nature communications 8 (1), 15986, 2017 | 126 | 2017 |
| Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells JR James, SS White, RW Clarke, AM Johansen, PD Dunne, DL Sleep, ... Proceedings of the National Academy of Sciences 104 (45), 17662-17667, 2007 | 94 | 2007 |
| The platelet receptor CLEC-2 is active as a dimer AA Watson, CM Christou, JR James, AE Fenton-May, GE Moncayo, ... Biochemistry 48 (46), 10988-10996, 2009 | 86 | 2009 |
| Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance Z Zhang, F Gothe, P Pennamen, JR James, D McDonald, CP Mata, ... Journal of Experimental Medicine 216 (6), 1311-1327, 2019 | 81 | 2019 |
| DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking PD Dunne, RA Fernandes, J McColl, JW Yoon, JR James, SJ Davis, ... Biophysical Journal 97 (4), L5-L7, 2009 | 73 | 2009 |
| Experimental challenge to a'rigorous' BRET analysis of GPCR oligomerization A Salahpour, B Masri Nature Methods 4 (8), 599-600, 2007 | 72 | 2007 |
| Tuning ITAM multiplicity on T cell receptors can control potency and selectivity to ligand density JR James Science signaling 11 (531), eaan1088, 2018 | 71 | 2018 |
| Glycoprotein VI oligomerization in cell lines and platelets O Berlanga, T BORI‐SANZ, JR James, J Frampton, SJ Davis, ... Journal of Thrombosis and Haemostasis 5 (5), 1026-1033, 2007 | 71 | 2007 |
| The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, ... Journal of Biological Chemistry 286 (37), 31993-32001, 2011 | 67 | 2011 |
| Distinctive properties of the hyaluronan-binding domain in the lymphatic endothelial receptor Lyve-1 and their implications for receptor function S Banerji, BRS Hide, JR James, MEM Noble, DG Jackson Journal of biological chemistry 285 (14), 10724-10735, 2010 | 61 | 2010 |
| Encoding optical control in LCK kinase to quantitatively investigate its activity in live cells A Liaunardy-Jopeace, BL Murton, M Mahesh, JW Chin, JR James Nature structural & molecular biology 24 (12), 1155-1163, 2017 | 58 | 2017 |
| A new pathway of CD5 glycoprotein-mediated T cell inhibition dependent on inhibitory phosphorylation of Fyn kinase M Bamberger, AM Santos, CM Gonçalves, MI Oliveira, JR James, ... Journal of Biological Chemistry 286 (35), 30324-30336, 2011 | 50 | 2011 |
| Ferroportin: lack of evidence for multimers LM Schimanski, H Drakesmith, C Talbott, K Horne, JR James, SJ Davis, ... Blood Cells, Molecules, and Diseases 40 (3), 360-369, 2008 | 31 | 2008 |
| Quantifying persistence in the T‐cell signaling network using an optically controllable antigen receptor MJ Harris, M Fuyal, JR James Molecular Systems Biology 17 (5), e10091, 2021 | 14 | 2021 |
| Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56Lck regulates T-cell activation independently of Lck/CD45 interactions M Kästle, C Merten, R Hartig, T Kaehne, A Liaunardy-Jopeace, ... Cell Communication and Signaling 18, 1-18, 2020 | 12 | 2020 |
