| Sub-fractionation of mitochondria and isolation of the proteins of oxidative phosphorylation R CI Mitochondria: a practical approach, 1987 | 332 | 1987 |
| Effect of detergent on “promiscuous” inhibitors AJ Ryan, NM Gray, PN Lowe, C Chung Journal of medicinal chemistry 46 (16), 3448-3451, 2003 | 288 | 2003 |
| Evidence for the presence of three distinct binding sites for the thioflavin T class of Alzheimer's disease PET imaging agents on β-amyloid peptide fibrils A Lockhart, L Ye, DB Judd, AT Merritt, PN Lowe, JL Morgenstern, G Hong, ... Journal of Biological Chemistry 280 (9), 7677-7684, 2005 | 262 | 2005 |
| Structure of Cdc42 bound to the GTPase binding domain of PAK A Morreale, M Venkatesan, HR Mott, D Owen, D Nietlispach, PN Lowe, ... Nature structural biology 7 (5), 384-388, 2000 | 247 | 2000 |
| Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK HR Mott, D Owen, D Nietlispach, PN Lowe, E Manser, L Lim, ED Laue Nature 399 (6734), 384-388, 1999 | 225 | 1999 |
| Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours. PJ Mitchell, KT Barker, JE Martindale, T Kamalati, PN Lowe, MJ Page, ... Oncogene 9 (8), 2383-2390, 1994 | 210 | 1994 |
| Delineation of the Cdc42/Rac-binding domain of p21-activated kinase G Thompson, D Owen, PA Chalk, PN Lowe Biochemistry 37 (21), 7885-7891, 1998 | 195 | 1998 |
| Use of the Glu-Glu-Phe C-terminal epitope for rapid purification of the catalytic domain of normal and mutant ras GTPase-activating proteins RH Skinner, S Bradley, AL Brown, NJ Johnson, S Rhodes, DK Stammers, ... Journal of biological chemistry 266 (22), 14163-14166, 1991 | 136 | 1991 |
| MgF3− as a transition state analog of phosphoryl transfer DL Graham, PN Lowe, GW Grime, M Marsh, K Rittinger, SJ Smerdon, ... Chemistry & biology 9 (3), 375-381, 2002 | 135 | 2002 |
| Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in … JF Eccleston, KJ Moore, L Morgan, RH Skinner, PN Lowe Journal of Biological Chemistry 268 (36), 27012-27019, 1993 | 123 | 1993 |
| Purification and characterization of pyruvate: ferredoxin oxidoreductase from the anaerobic protozoon Trichomonas vaginalis K Williams, PN Lowe, PF Leadlay Biochemical Journal 246 (2), 529-536, 1987 | 116 | 1987 |
| The Conserved Arginine in Rho-GTPase-Activating Protein Is Essential for Efficient Catalysis but Not for Complex Formation with Rho⊙ GDP and Aluminum Fluoride DL Graham, JF Eccleston, PN Lowe Biochemistry 38 (3), 985-991, 1999 | 108 | 1999 |
| Interaction of GTPase activating proteins (GAPs) with p21ras measured by a novel fluorescence anisotropy method. Essential role of Arg-903 of GAP in activation of GTP … GG Brownbridge, PN Lowe, KJ Moore, RH Skinner, MR Webb Journal of Biological Chemistry 268 (15), 10914-10919, 1993 | 102 | 1993 |
| The IQGAP1-Rac1 and IQGAP1-Cdc42 interactions: interfaces differ between the complexes D Owen, LJ Campbell, K Littlefield, KA Evetts, Z Li, DB Sacks, PN Lowe, ... Journal of Biological Chemistry 283 (3), 1692-1704, 2008 | 95 | 2008 |
| Residues in Cdc42 that specify binding to individual CRIB effector proteins D Owen, HR Mott, ED Laue, PN Lowe Biochemistry 39 (6), 1243-1250, 2000 | 94 | 2000 |
| Interactions between the mitochondrial adenosinetriphosphatase and periodate-oxidized adenosine 5'-triphosphate, an affinity label for adenosine 5'-triphosphate binding sites PN Lowe, RB Beechey Biochemistry 21 (17), 4073-4082, 1982 | 93 | 1982 |
| Dual role of a single multienzyme complex in the oxidative decarboxylation of pyruvate and branched-chain 2-oxo acids in Bacillus subtilis PN Lowe, JA Hodgson, RN Perham Biochemical Journal 215 (1), 133-140, 1983 | 85 | 1983 |
| Kinetics of inorganic phosphate release during the interaction of p21ras with the GTPase-activating proteins, p120-GAP and neurofibromin AE Nixon, M Brune, PN Lowe, MR Webb Biochemistry 34 (47), 15592-15598, 1995 | 81 | 1995 |
| Measurement of dissociation constants of inhibitors binding to Src SH2 domain protein by non‐covalent electrospray ionization mass spectrometry SWA Bligh, T Haley, PN Lowe Journal of Molecular Recognition 16 (3), 139-148, 2003 | 75 | 2003 |
| Equilibrium and Kinetic Measurements Reveal Rapidly Reversible Binding of Ras to Raf (∗) C Gorman, RH Skinner, JV Skelly, S Neidle, PN Lowe Journal of Biological Chemistry 271 (12), 6713-6719, 1996 | 73 | 1996 |
