S Kumar, E Wittmann, Christoph, Heinzle
Biotechnology Letters, 1-10, 2004
|Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease|
C Venegas, S Kumar, BS Franklin, T Dierkes, R Brinkschulte, D Tejera, ...
Nature 552 (7685), 355-361, 2017
|Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation|
MP Kummer, M Hermes, A Delekarte, T Hammerschmidt, S Kumar, ...
Neuron 71 (5), 833-844, 2011
|Extracellular phosphorylation of the amyloid β‐peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease|
S Kumar, N Rezaei‐Ghaleh, D Terwel, DR Thal, M Richard, M Hoch, ...
The EMBO journal 30 (11), 2255-2265, 2011
|Phosphorylation of amyloid beta (Aβ) peptides–A trigger for formation of toxic aggregates in Alzheimer's disease|
S Kumar, J Walter
Aging (Albany NY) 3 (8), 803, 2011
|Statins promote the degradation of extracellular amyloid β-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion|
IY Tamboli, E Barth, L Christian, M Siepmann, S Kumar, S Singh, ...
Journal of biological chemistry 285 (48), 37405-37414, 2010
|Identification of Low Molecular Weight Pyroglutamate Aβ Oligomers in Alzheimer Disease A NOVEL TOOL FOR THERAPY AND DIAGNOSIS|
O Wirths, C Erck, H Martens, A Harmeier, C Geumann, S Jawhar, S Kumar, ...
Journal of Biological Chemistry 285 (53), 41517-41524, 2010
|Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer’s disease|
A Rijal Upadhaya, I Kosterin, S Kumar, CAF von Arnim, H Yamaguchi, ...
Brain 137 (3), 887-903, 2014
|[18F] flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of amyloid-β pathology|
DR Thal, TG Beach, M Zanette, K Heurling, A Chakrabarty, A Ismail, ...
Alzheimer's & Dementia 11 (8), 975-985, 2015
|Early intraneuronal accumulation and increased aggregation of phosphorylated Abeta in a mouse model of Alzheimer’s disease|
S Kumar, O Wirths, S Theil, J Gerth, TA Bayer, J Walter
Acta neuropathologica 125 (5), 699-709, 2013
|Phosphorylation of amyloid-β peptide at serine 8 attenuates its clearance via insulin-degrading and angiotensin-converting enzymes|
S Kumar, S Singh, D Hinze, M Josten, HG Sahl, M Siepmann, J Walter
Journal of Biological Chemistry 287 (11), 8641-8651, 2012
|Generation of aggregation prone N-terminally truncated amyloid β peptides by meprin β depends on the sequence specificity at the cleavage site|
C Schönherr, J Bien, S Isbert, R Wichert, J Prox, H Altmeppen, S Kumar, ...
Molecular neurodegeneration 11 (1), 19, 2016
|Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein …|
AR Upadhaya, E Capetillo-Zarate, I Kosterin, D Abramowski, S Kumar, ...
Neurobiology of aging 33 (11), 2641-2660, 2012
|Phosphorylation of the amyloid β-peptide at Ser26 stabilizes oligomeric assembly and increases neurotoxicity|
S Kumar, O Wirths, K Stüber, P Wunderlich, P Koch, S Theil, ...
Acta neuropathologica 131 (4), 525-537, 2016
|Phosphorylation modifies the molecular stability of β-amyloid deposits|
N Rezaei-Ghaleh, M Amininasab, S Kumar, J Walter, M Zweckstetter
Nature communications 7, 11359, 2016
|Analysis of 13C labeling enrichment in microbial culture applying metabolic tracer experiments using gas chromatography-combustion-isotope ratio mass spectrometry.|
H Elmar, Y Yongbo, K Sathish, W Christoph, G Matthias, ...
Analytical Biochemistry, 202-210, 2008
|BRI2 protein regulates β-amyloid degradation by increasing levels of secreted insulin-degrading enzyme (IDE)|
E Kilger, A Buehler, H Woelfing, S Kumar, SA Kaeser, A Nagarathinam, ...
Journal of Biological Chemistry 286 (43), 37446-37457, 2011
|Turn plasticity distinguishes different modes of amyloid-β aggregation|
N Rezaei-Ghaleh, M Amininasab, K Giller, S Kumar, A Stündl, ...
Journal of the American Chemical Society 136 (13), 4913-4919, 2014
|Identification of a possible control element, Mt5, in the major noncoding region of mitochondrial DNA by intraspecific nucleotide conservation.|
K Ohno, M Tanaka, H Suzuki, T Ohbayashi, S Ikebe, H Ino, S Kumar, ...
Biochemistry international 24 (2), 263, 1991
|Casein kinase 2 dependent phosphorylation of neprilysin regulates receptor tyrosine kinase signaling to Akt|
M Siepmann, S Kumar, G Mayer, J Walter
PLoS One 5 (10), e13134, 2010