| Replicable and coupled changes in innate and adaptive immune gene expression in two case-control studies of blood microarrays in major depressive disorder GGR Leday, PE Vértes, S Richardson, JR Greene, T Regan, S Khan, ... Biological psychiatry 83 (1), 70-80, 2018 | 173 | 2018 |
| Immune cell gene signatures for profiling the microenvironment of solid tumors AJ Nirmal, T Regan, BB Shih, DA Hume, AH Sims, TC Freeman Cancer immunology research 6 (11), 1388-1400, 2018 | 171 | 2018 |
| Identification of TLR10 as a key mediator of the inflammatory response to Listeria monocytogenes in intestinal epithelial cells and macrophages T Regan, K Nally, R Carmody, A Houston, F Shanahan, J Macsharry, ... The Journal of Immunology 191 (12), 6084-6092, 2013 | 166 | 2013 |
| Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection B Li, SM Clohisey, BS Chia, B Wang, A Cui, T Eisenhaure, LD Schweitzer, ... Nature communications 11 (1), 164, 2020 | 161 | 2020 |
| Structural and kinetic determinants of protease substrates JC Timmer, W Zhu, C Pop, T Regan, SJ Snipas, AM Eroshkin, SJ Riedl, ... Nature structural & molecular biology 16 (10), 1101-1108, 2009 | 146 | 2009 |
| Effects of immunomodulatory drugs on depressive symptoms: a mega-analysis of randomized, placebo-controlled clinical trials in inflammatory disorders GM Wittenberg, A Stylianou, Y Zhang, Y Sun, A Gupta, PS Jagannatha, ... Molecular psychiatry 25 (6), 1275-1285, 2020 | 125 | 2020 |
| Pleiotropic impacts of macrophage and microglial deficiency on development in rats with targeted mutation of the Csf1r locus C Pridans, A Raper, GM Davis, J Alves, KA Sauter, L Lefevre, T Regan, ... The Journal of Immunology 201 (9), 2683-2699, 2018 | 102 | 2018 |
| Assembly of a parts list of the human mitotic cell cycle machinery B Giotti, SH Chen, MW Barnett, T Regan, T Ly, S Wiemann, DA Hume, ... Journal of molecular cell biology 11 (8), 703-718, 2019 | 68 | 2019 |
| Characterisation of the British honey bee metagenome T Regan, MW Barnett, DR Laetsch, SJ Bush, D Wragg, GE Budge, ... Nature communications 9 (1), 4995, 2018 | 63 | 2018 |
| Efficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system RL Gratacap, T Regan, CE Dehler, SAM Martin, P Boudinot, B Collet, ... BMC biotechnology 20, 1-9, 2020 | 51 | 2020 |
| Genetic improvement technologies to support the sustainable growth of UK aquaculture T Regan, TP Bean, T Ellis, A Davie, S Carboni, H Migaud, RD Houston Reviews in aquaculture 13 (4), 1958-1985, 2021 | 37 | 2021 |
| Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ... Database 2019, 2019 | 35 | 2019 |
| Graphia: A platform for the graph-based visualisation and analysis of complex data TC Freeman, S Horsewell, A Patir, J Harling-Lee, T Regan, BB Shih, ... BioRxiv, 2020.09. 02.279349, 2020 | 34 | 2020 |
| Graphia: A platform for the graph-based visualisation and analysis of high dimensional data TC Freeman, S Horsewell, A Patir, J Harling-Lee, T Regan, BB Shih, ... PLoS computational biology 18 (7), e1010310, 2022 | 33 | 2022 |
| Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages MRC Immunopsychiatry Consortium Regan Tim Gill Andrew C Clohisey Sara M ... Journal of leukocyte biology 103 (4), 681-692, 2018 | 30 | 2018 |
| Potential of genomic technologies to improve disease resistance in molluscan aquaculture RWA Potts, AP Gutierrez, CS Penaloza, T Regan, TP Bean, RD Houston Philosophical Transactions of the Royal Society B 376 (1825), 20200168, 2021 | 25 | 2021 |
| Tracing innate immune defences along the path of Listeria monocytogenes infection T Regan, J MacSharry, E Brint Immunology and Cell Biology 92 (7), 563-569, 2014 | 22 | 2014 |
| Immune cell gene signatures for profiling the microenvironment of solid tumors. Cancer Immunol. Res. 2018; 6: 1388–1400. doi: 10.1158/2326-6066 AJ Nirmal, T Regan, BB Shih, DA Hume, AH Sims, TC Freeman CIR-18-0342.[Abstract][CrossRef][Google Scholar], 0 | 20 | |
| Intestinal expression of Fas and Fas ligand is upregulated by bacterial signaling through TLR4 and TLR5, with activation of Fas modulating intestinal TLR-mediated inflammation P Fernandes, C O’Donnell, C Lyons, J Keane, T Regan, S O’Brien, ... The Journal of Immunology 193 (12), 6103-6113, 2014 | 16 | 2014 |
| Chromosome‐level reference genome for European flat oyster (Ostrea edulis L.) MK Gundappa, C Peñaloza, T Regan, I Boutet, A Tanguy, RD Houston, ... Evolutionary applications 15 (11), 1713-1729, 2022 | 14 | 2022 |
Tom C. FreemanProfessor of Systems Immunology, University of EdinburghVerified email at roslin.ed.ac.uk
