| Rivaroxaban versus warfarin in nonvalvular atrial fibrillation MR Patel, KW Mahaffey, J Garg, G Pan, DE Singer, W Hacke, G Breithardt, ... New England Journal of Medicine, 2011 | 11236 | 2011 |
| Edoxaban versus warfarin in patients with atrial fibrillation RP Giugliano, CT Ruff, E Braunwald, SA Murphy, SD Wiviott, JL Halperin, ... New England Journal of Medicine 369 (22), 2093-2104, 2013 | 5591 | 2013 |
| The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research N Percie du Sert, V Hurst, A Ahluwalia, S Alam, MT Avey, M Baker, ... Journal of Cerebral Blood Flow & Metabolism 40 (9), 1769-1777, 2020 | 4077 | 2020 |
| 1,026 experimental treatments in acute stroke VE O'Collins, MR Macleod, GA Donnan, LL Horky, BH Van Der Worp, ... Annals of neurology 59 (3), 467-477, 2006 | 1661 | 2006 |
| Increasing value and reducing waste in research design, conduct, and analysis JPA Ioannidis, S Greenland, MA Hlatky, MJ Khoury, MR Macleod, ... The Lancet 383 (9912), 166-175, 2014 | 1513 | 2014 |
| The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST … P Sandercock, JM Wardlaw, RI Lindley, M Dennis, G Cohen, G Murray Lancet 379 (9834), 2352-2363, 2012 | 1440 | 2012 |
| Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study A Varatharaj, N Thomas, MA Ellul, NWS Davies, TA Pollak, EL Tenorio, ... The Lancet Psychiatry 7 (10), 875-882, 2020 | 1430 | 2020 |
| Update of the stroke therapy academic industry roundtable preclinical recommendations M Fisher, G Feuerstein, DW Howells, PD Hurn, TA Kent, SI Savitz, EH Lo Stroke 40 (6), 2244-2250, 2009 | 1386 | 2009 |
| Can animal models of disease reliably inform human studies? HB Van der Worp, DW Howells, ES Sena, MJ Porritt, S Rewell, V O'Collins, ... PLoS medicine 7 (3), e1000245, 2010 | 1362 | 2010 |
| Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: a systematic review and meta-analysis M Seretny, GL Currie, ES Sena, S Ramnarine, R Grant, MR MacLeod, ... Pain® 155 (12), 2461-2470, 2014 | 1246 | 2014 |
| Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0 NP Du Sert, A Ahluwalia, S Alam, MT Avey, M Baker, WJ Browne, A Clark, ... PLoS biology 18 (7), e3000411, 2020 | 1242 | 2020 |
| A call for transparent reporting to optimize the predictive value of preclinical research SC Landis, SG Amara, K Asadullah, CP Austin, R Blumenstein, ... Nature 490 (7419), 187-191, 2012 | 1143 | 2012 |
| Ischaemic stroke BCV Campbell, DA De Silva, MR Macleod, SB Coutts, LH Schwamm, ... Nature reviews Disease primers 5 (1), 70, 2019 | 1082 | 2019 |
| Biomedical research: increasing value, reducing waste MR Macleod, S Michie, I Roberts, U Dirnagl, I Chalmers, JPA Ioannidis, ... The Lancet 383 (9912), 101-104, 2014 | 1035 | 2014 |
| Vorapaxar in the Secondary Prevention of Atherothrombotic Events DA Morrow, E Braunwald, MP Bonaca, SF Ameriso, AJ Dalby, MP Fish, ... New England Journal of Medicine, 2012 | 974 | 2012 |
| Comparison of treatment effects between animal experiments and clinical trials: systematic review P Perel, I Roberts, E Sena, P Wheble, C Briscoe, P Sandercock, ... Bmj 334 (7586), 197, 2007 | 932 | 2007 |
| Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke H Ma, BCV Campbell, MW Parsons, L Churilov, CR Levi, C Hsu, ... New England Journal of Medicine 380 (19), 1795-1803, 2019 | 798 | 2019 |
| General anaesthesia versus local anaesthesia for carotid surgery (GALA): a multicentre, randomised controlled trial GALA Trial Collaborative Group The Lancet 372 (9656), 2132-2142, 2008 | 692 | 2008 |
| Pooling of animal experimental data reveals influence of study design and publication bias MR Macleod, T O’Collins, DW Howells, GA Donnan Stroke 35 (5), 1203-1208, 2004 | 613 | 2004 |
| Publication bias in reports of animal stroke studies leads to major overstatement of efficacy ES Sena, HB Van Der Worp, PMW Bath, DW Howells, MR Macleod PLoS biology 8 (3), e1000344, 2010 | 603 | 2010 |
Emily S SenaUniversity of EdinburghVerified email at ed.ac.uk
