Andrea Scozzafava
Andrea Scozzafava
Professore di chimica, Universitŕ di Firenze
Verified email at unifi.it
TitleCited byYear
Carbonic anhydrase inhibitors
CT Supuran, A Scozzafava, A Casini
Medicinal research reviews 23 (2), 146-189, 2003
1198*2003
Hypoxia activates the capacity of tumor‐associated carbonic anhydrase IX to acidify extracellular pH
E Švastová, A Hulı́ková, M Rafajová, M Zat'ovičová, A Gibadulinová, ...
FEBS letters 577 (3), 439-445, 2004
6102004
Anticancer and antiviral sulfonamides
A Scozzafava, T Owa, A Mastrolorenzo, CT Supuran
Current medicinal chemistry 10 (11), 925-953, 2003
5602003
Carbonic anhydrase inhibitors and their therapeutic potential
CT Supuran, A Scozzafava
Expert Opinion on Therapeutic Patents 10 (5), 575-600, 2000
5022000
Carbonic anhydrases as targets for medicinal chemistry
CT Supuran, A Scozzafava
Bioorganic & medicinal chemistry 15 (13), 4336-4350, 2007
5002007
Carbonic anhydrase: its inhibitors and activators
CT Supuran, A Scozzafava, J Conway
CRC press, 2004
435*2004
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition
A Weber, A Casini, A Heine, D Kuhn, CT Supuran, A Scozzafava, G Klebe
Journal of medicinal chemistry 47 (3), 550-557, 2004
4322004
Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors
Y Lou, PC McDonald, A Oloumi, S Chia, C Ostlund, A Ahmadi, A Kyle, ...
Cancer research 71 (9), 3364-3376, 2011
4112011
Protease inhibitors of the sulfonamide type: anticancer, antiinflammatory, and antiviral agents
CT Supuran, A Casini, A Scozzafava
Medicinal Research Reviews 23 (5), 535-558, 2003
3692003
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
V Alterio, M Hilvo, A Di Fiore, CT Supuran, P Pan, S Parkkila, A Scaloni, ...
Proceedings of the National Academy of Sciences 106 (38), 16233-16238, 2009
3652009
Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors
A Maresca, C Temperini, H Vu, NB Pham, SA Poulsen, A Scozzafava, ...
Journal of the American Chemical Society 131 (8), 3057-3062, 2009
3432009
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis
F Pacchiano, F Carta, PC McDonald, Y Lou, D Vullo, A Scozzafava, ...
Journal of medicinal chemistry 54 (6), 1896-1902, 2011
3002011
Applications of carbonic anhydrase inhibitors and activators in therapy
CT Supuran, A Scozzafava
Expert Opinion on Therapeutic Patents 12 (2), 217-242, 2002
2962002
Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins
A Maresca, C Temperini, L Pochet, B Masereel, A Scozzafava, ...
Journal of medicinal chemistry 53 (1), 335-344, 2009
2702009
Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome
G Barbaro, A Scozzafava, A Mastrolorenzo, CT Supuran
Current pharmaceutical design 11 (14), 1805-1843, 2005
2672005
Carbonic anhydrase inhibitors: sulfonamides as antitumor agents?
CT Supuran, F Briganti, S Tilli, WR Chegwidden, A Scozzafava
Bioorganic & medicinal chemistry 9 (3), 703-714, 2001
2672001
Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX
F Abbate, A Casini, T Owa, A Scozzafava, CT Supuran
Bioorganic & medicinal chemistry letters 14 (1), 217-223, 2004
2602004
Carbonic anhydrase and matrix metalloproteinase inhibitors: sulfonylated amino acid hydroxamates with MMP inhibitory properties act as efficient inhibitors of CA isozymes I, II …
A Scozzafava, CT Supuran
Journal of medicinal Chemistry 43 (20), 3677-3687, 2000
2522000
Carbonic Anhydrase Activators:  X-ray Crystallographic and Spectroscopic Investigations for the Interaction of Isozymes I and II with Histamine,
F Briganti, S Mangani, P Orioli, A Scozzafava, G Vernaglione, CT Supuran
Biochemistry 36 (34), 10384-10392, 1997
2431997
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes
M Hilvo, L Baranauskiene, AM Salzano, A Scaloni, D Matulis, A Innocenti, ...
Journal of Biological Chemistry 283 (41), 27799-27809, 2008
2412008
The system can't perform the operation now. Try again later.
Articles 1–20