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| PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells C Pirazzi, L Valenti, BM Motta, P Pingitore, K Hedfalk, RM Mancina, ... Human molecular genetics 23 (15), 4077-4085, 2014 | 372 | 2014 |
| Recombinant PNPLA3 protein shows triglyceride hydrolase activity and its I148M mutation results in loss of function P Pingitore, C Pirazzi, RM Mancina, BM Motta, C Indiveri, A Pujia, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2014 | 221 | 2014 |
| Crystal structure of a yeast aquaporin at 1.15 Å reveals a novel gating mechanism G Fischer, U Kosinska-Eriksson, C Aponte-Santamaría, M Palmgren, ... PLoS biology 7 (6), e1000130, 2009 | 205 | 2009 |
| Structural insights into eukaryotic aquaporin regulation S Törnroth-Horsefield, K Hedfalk, G Fischer, K Lindkvist-Petersson, ... FEBS letters 584 (12), 2580-2588, 2010 | 195 | 2010 |
| Aquaporin gating K Hedfalk, S Törnroth-Horsefield, M Nyblom, U Johanson, P Kjellbom, ... Current opinion in structural biology 16 (4), 447-456, 2006 | 151 | 2006 |
| X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking A Frick, UK Eriksson, F de Mattia, F Öberg, K Hedfalk, R Neutze, ... Proceedings of the National Academy of Sciences 111 (17), 6305-6310, 2014 | 136 | 2014 |
| Reconstitution of water channel function of an aquaporin overexpressed and purified from Pichia pastoris M Karlsson, D Fotiadis, S Sjövall, I Johansson, K Hedfalk, A Engel, ... FEBS letters 537 (1-3), 68-72, 2003 | 134 | 2003 |
| Structural and functional analysis of SoPIP2; 1 mutants adds insight into plant aquaporin gating M Nyblom, A Frick, Y Wang, M Ekvall, K Hallgren, K Hedfalk, R Neutze, ... Journal of molecular biology 387 (3), 653-668, 2009 | 117 | 2009 |
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| A short regulatory domain restricts glycerol transport through yeast Fps1p MJ Tamás, S Karlgren, RM Bill, K Hedfalk, L Allegri, M Ferreira, ... Journal of Biological Chemistry 278 (8), 6337-6345, 2003 | 116 | 2003 |
| CO2 permeability of cell membranes is regulated by membrane cholesterol and protein gas channels F Itel, S Al‐Samir, F Öberg, M Chami, M Kumar, CT Supuran, PMT Deen, ... The FASEB Journal 26 (12), 5182-5191, 2012 | 109 | 2012 |
| Characterization of aquaporin-driven hydrogen peroxide transport H Wang, S Schoebel, F Schmitz, H Dong, K Hedfalk Biochimica et Biophysica Acta (BBA)-Biomembranes 1862 (2), 183065, 2020 | 86 | 2020 |
| Glycosylation increases the thermostability of human aquaporin 10 protein F Öberg, J Sjöhamn, G Fischer, A Moberg, A Pedersen, R Neutze, ... Journal of Biological Chemistry 286 (36), 31915-31923, 2011 | 80 | 2011 |
| Design of improved membrane protein production experiments: quantitation of the host response N Bonander, K Hedfalk, C Larsson, P Mostad, C Chang, L Gustafsson, ... Protein science 14 (7), 1729-1740, 2005 | 80 | 2005 |
| Exceptional overproduction of a functional human membrane protein M Nyblom, F Öberg, K Lindkvist-Petersson, K Hallgren, H Findlay, ... Protein expression and purification 56 (1), 110-120, 2007 | 78 | 2007 |
| A regulatory domain in the C-terminal extension of the yeast glycerol channel Fps1p K Hedfalk, RM Bill, JGL Mullins, S Karlgren, C Filipsson, J Bergstrom, ... Journal of Biological Chemistry 279 (15), 14954-14960, 2004 | 76 | 2004 |
| Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris—Functional and kinetic asymmetry revealed in proteoliposomes P Pingitore, L Pochini, M Scalise, M Galluccio, K Hedfalk, C Indiveri Biochimica Et Biophysica Acta (BBA)-Biomembranes 1828 (9), 2238-2246, 2013 | 75 | 2013 |
| Transport mechanism and regulatory properties of the human amino acid transporter ASCT2 (SLC1A5) M Scalise, L Pochini, S Panni, P Pingitore, K Hedfalk, C Indiveri Amino Acids 46, 2463-2475, 2014 | 73 | 2014 |
| Improving recombinant eukaryotic membrane protein yields in Pichia pastoris: the importance of codon optimization and clone selection F Öberg, J Sjöhamn, MT Conner, RM Bill, K Hedfalk Molecular membrane biology 28 (6), 398-411, 2011 | 64 | 2011 |
