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Lorna Farrelly
Lorna Farrelly
Postdoctoral Fellow, Department of Pharmacology & Therapeutics/Neuroscience at Mount Sinai
Verified email at mssm.edu
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Cited by
Cited by
Year
Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3
LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ...
Nature 567 (7749), 535-539, 2019
4082019
Critical role of histone turnover in neuronal transcription and plasticity
I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ...
Neuron 87 (1), 77-94, 2015
3262015
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking
AE Lepack, CT Werner, AF Stewart, SL Fulton, P Zhong, LA Farrelly, ...
Science 368 (6487), 197-201, 2020
2102020
Aberrant H3. 3 dynamics in NAc promote vulnerability to depressive-like behavior
AE Lepack, RC Bagot, CJ Peña, YHE Loh, LA Farrelly, Y Lu, SK Powell, ...
Proceedings of the National Academy of Sciences 113 (44), 12562-12567, 2016
632016
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout
S Zhao, KN Chuh, B Zhang, BE Dul, RE Thompson, LA Farrelly, X Liu, ...
Proceedings of the National Academy of Sciences 118 (6), e2016742118, 2021
562021
Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence
L Farrelly, M Föcking, Y Piontkewitz, P Dicker, J English, K Wynne, ...
Developmental neuroscience 37 (1), 43-55, 2015
502015
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia
LA Farrelly, S Zheng, N Schrode, A Topol, NV Bhanu, RM Bastle, ...
Nature communications 13 (1), 2195, 2022
262022
An emerging perspective on ‘histone code’mediated regulation of neural plasticity and disease
LA Farrelly, I Maze
Current opinion in neurobiology 59, 157-163, 2019
222019
Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex
LA Farrelly, P Dicker, K Wynne, J English, G Cagney, M Föcking, ...
Proteomics 14 (12), 1574-1578, 2014
172014
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome
SL Fulton, W Wenderski, AE Lepack, AL Eagle, T Fanutza, RM Bastle, ...
Nature communications 13 (1), 6384, 2022
132022
Current proteomic methods to investigate the dynamics of histone turnover in the central nervous system
LA Farrelly, BD Dill, H Molina, MR Birtwistle, I Maze
Methods in enzymology 574, 331-354, 2016
62016
The effects of prenatal iron deficiency and risperidone treatment on the rat frontal cortex: a proteomic analysis
L Farrelly, MV Rosato‐Siri, M Föcking, M Codagnone, A Reines, P Dicker, ...
Proteomics 17 (17-18), 1600407, 2017
52017
Histone serotonylation in dorsal raphe nucleus contributes to stress-and antidepressant-mediated gene expression and behavior
A Al-Kachak, G Di Salvo, SL Fulton, JC Chan, LA Farrelly, AE Lepack, ...
Nature Communications 15 (1), 5042, 2024
32024
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior.
A Al-Kachak, SL Fulton, LA Farrelly, AE Lepack, RM Bastle, L Kong, ...
Biorxiv: the Preprint Server for Biology, 2023
32023
Early-life stress alters chromatin modifications in VTA to prime stress sensitivity
LT Geiger, JAR Balouek, LA Farrelly, AS Chen, M Tang, SN Bennett, ...
bioRxiv, 2024.03. 14.584631, 2024
22024
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-and antidepressant-mediated gene expression and behavior
A Al-Kachak, SL Fulton, G Di Salvo, JC Chan, LA Farrelly, AE Lepack, ...
bioRxiv, 2023
12023
Insights from Proteomic Studies on Schizophrenia Preclinical Models: What Can We Learn for Drug Discovery?
LA Farrelly, M Föcking, DR Cotter
Proteomics and Metabolomics in Psychiatry 29, 56-73, 2014
12014
Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation
AF Stewart, SL Fulton, R Durand-de Cuttoli, RE Thompson, PJ Chen, ...
bioRxiv, 2024
2024
A Female‐specific Role of RGS20 in Transcriptional, Epigenomic and Behavioral Responses to Chronic Pain
A Ruiz, S Gaspari, L Farrelly, C Polizu, K Pryce, A Ramakrishnan, ...
The FASEB Journal 35, 2021
2021
T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS
L Farrelly, S Zhang, E Flaherty, A Topol, N Schrode, R Bastle, N Bhanu, ...
Schizophrenia Bulletin 46 (Suppl 1), S234, 2020
2020
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