Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ... Nature 567 (7749), 535-539, 2019 | 408 | 2019 |
Critical role of histone turnover in neuronal transcription and plasticity I Maze, W Wenderski, KM Noh, RC Bagot, N Tzavaras, I Purushothaman, ... Neuron 87 (1), 77-94, 2015 | 326 | 2015 |
Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking AE Lepack, CT Werner, AF Stewart, SL Fulton, P Zhong, LA Farrelly, ... Science 368 (6487), 197-201, 2020 | 210 | 2020 |
Aberrant H3. 3 dynamics in NAc promote vulnerability to depressive-like behavior AE Lepack, RC Bagot, CJ Peña, YHE Loh, LA Farrelly, Y Lu, SK Powell, ... Proceedings of the National Academy of Sciences 113 (44), 12562-12567, 2016 | 63 | 2016 |
Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout S Zhao, KN Chuh, B Zhang, BE Dul, RE Thompson, LA Farrelly, X Liu, ... Proceedings of the National Academy of Sciences 118 (6), e2016742118, 2021 | 56 | 2021 |
Maternal immune activation induces changes in myelin and metabolic proteins, some of which can be prevented with risperidone in adolescence L Farrelly, M Föcking, Y Piontkewitz, P Dicker, J English, K Wynne, ... Developmental neuroscience 37 (1), 43-55, 2015 | 50 | 2015 |
Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia LA Farrelly, S Zheng, N Schrode, A Topol, NV Bhanu, RM Bastle, ... Nature communications 13 (1), 2195, 2022 | 26 | 2022 |
An emerging perspective on ‘histone code’mediated regulation of neural plasticity and disease LA Farrelly, I Maze Current opinion in neurobiology 59, 157-163, 2019 | 22 | 2019 |
Adolescent Risperidone treatment alters protein expression associated with protein trafficking and cellular metabolism in the adult rat prefrontal cortex LA Farrelly, P Dicker, K Wynne, J English, G Cagney, M Föcking, ... Proteomics 14 (12), 1574-1578, 2014 | 17 | 2014 |
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome SL Fulton, W Wenderski, AE Lepack, AL Eagle, T Fanutza, RM Bastle, ... Nature communications 13 (1), 6384, 2022 | 13 | 2022 |
Current proteomic methods to investigate the dynamics of histone turnover in the central nervous system LA Farrelly, BD Dill, H Molina, MR Birtwistle, I Maze Methods in enzymology 574, 331-354, 2016 | 6 | 2016 |
The effects of prenatal iron deficiency and risperidone treatment on the rat frontal cortex: a proteomic analysis L Farrelly, MV Rosato‐Siri, M Föcking, M Codagnone, A Reines, P Dicker, ... Proteomics 17 (17-18), 1600407, 2017 | 5 | 2017 |
Histone serotonylation in dorsal raphe nucleus contributes to stress-and antidepressant-mediated gene expression and behavior A Al-Kachak, G Di Salvo, SL Fulton, JC Chan, LA Farrelly, AE Lepack, ... Nature Communications 15 (1), 5042, 2024 | 3 | 2024 |
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-induced gene expression and behavior. A Al-Kachak, SL Fulton, LA Farrelly, AE Lepack, RM Bastle, L Kong, ... Biorxiv: the Preprint Server for Biology, 2023 | 3 | 2023 |
Early-life stress alters chromatin modifications in VTA to prime stress sensitivity LT Geiger, JAR Balouek, LA Farrelly, AS Chen, M Tang, SN Bennett, ... bioRxiv, 2024.03. 14.584631, 2024 | 2 | 2024 |
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress-and antidepressant-mediated gene expression and behavior A Al-Kachak, SL Fulton, G Di Salvo, JC Chan, LA Farrelly, AE Lepack, ... bioRxiv, 2023 | 1 | 2023 |
Insights from Proteomic Studies on Schizophrenia Preclinical Models: What Can We Learn for Drug Discovery? LA Farrelly, M Föcking, DR Cotter Proteomics and Metabolomics in Psychiatry 29, 56-73, 2014 | 1 | 2014 |
Hippocampal γCaMKII dopaminylation promotes synaptic-to-nuclear signaling and memory formation AF Stewart, SL Fulton, R Durand-de Cuttoli, RE Thompson, PJ Chen, ... bioRxiv, 2024 | | 2024 |
A Female‐specific Role of RGS20 in Transcriptional, Epigenomic and Behavioral Responses to Chronic Pain A Ruiz, S Gaspari, L Farrelly, C Polizu, K Pryce, A Ramakrishnan, ... The FASEB Journal 35, 2021 | | 2021 |
T9. EPIGENETIC PROFILING IN SCHIZOPHRENIA DERIVED HUMAN INDUCED PLURIPOTENT STEM CELLS (HIPSCS) AND NEURONS L Farrelly, S Zhang, E Flaherty, A Topol, N Schrode, R Bastle, N Bhanu, ... Schizophrenia Bulletin 46 (Suppl 1), S234, 2020 | | 2020 |