Alexander Mazein
Alexander Mazein
Luxembourg Centre for Systems Biomedicine, University of Luxembourg
Verified email at uni.lu
TitleCited byYear
A community-driven global reconstruction of human metabolism
I Thiele, N Swainston, RMT Fleming, A Hoppe, S Sahoo, MK Aurich, ...
Nature Biotechnology, 2013
8402013
The Edinburgh human metabolic network reconstruction and its functional analysis
H Ma, A Sorokin, A Mazein, A Selkov, E Selkov, O Demin, I Goryanin
Molecular systems biology 3 (1), 2007
4222007
U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics
D Lefaudeux, B De Meulder, MJ Loza, N Peffer, A Rowe, F Baribaud, ...
Journal of Allergy and Clinical Immunology 139 (6), 1797-1807, 2017
1112017
A comprehensive machine-readable view of the mammalian cholesterol biosynthesis pathway
A Mazein, S Watterson, WY Hsieh, WJ Griffiths, P Ghazal
Biochemical Pharmacology 86 (1), 56-66, 2013
492013
Pathway discovery using transcriptomic profiles in adult-onset severe asthma
PP Hekking, MJ Loza, S Pavlidis, B De Meulder, D Lefaudeux, F Baribaud, ...
Journal of Allergy and Clinical Immunology 141 (4), 1280-1290, 2018
412018
Representing and querying disease networks using graph databases
A Lysenko, IA Roznovăţ, M Saqi, A Mazein, CJ Rawlings, C Auffray
BioData Mining 9 (1), 23, 2016
322016
MINERVA—a platform for visualization and curation of molecular interaction networks
P Gawron, M Ostaszewski, V Satagopam, S Gebel, A Mazein, M Kuzma, ...
NPJ Systems Biology and Applications 2, 16020, 2016
272016
A model of flux regulation in the cholesterol biosynthesis pathway: immune mediated graduated flux reduction versus statin-like led stepped flux reduction
S Watterson, ML Guerriero, M Blanc, A Mazein, L Loewe, KA Robertson, ...
Biochimie 95 (3), 613-621, 2013
262013
Systems medicine: the future of medical genomics, healthcare, and wellness
M Saqi, J Pellet, I Roznovat, A Mazein, S Ballereau, B De Meulder, ...
Systems Medicine, 43-60, 2016
232016
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation
Z Jevnikar, J Östling, E Ax, J Calvén, K Thörn, E Israelsson, L Öberg, ...
Journal of Allergy and Clinical Immunology 143 (2), 577-590, 2019
122019
Community-driven roadmap for integrated disease maps
M Ostaszewski, S Gebel, I Kuperstein, A Mazein, A Zinovyev, U Dogrusoz, ...
Briefings in Bioinformatics 10, 2018
112018
EpiGeNet: a graph database of interdependencies between genetic and epigenetic events in colorectal cancer
I Balaur, M Saqi, A Barat, A Lysenko, A Mazein, CJ Rawlings, HJ Ruskin, ...
Journal of Computational Biology 24 (10), 969-980, 2017
112017
Systems medicine disease maps: community-driven comprehensive representation of disease mechanisms
A Mazein, M Ostaszewski, I Kuperstein, S Watterson, N Le Novčre, ...
NPJ Systems Biology and Applications 4 (1), 21, 2018
102018
Recon2Neo4j: applying graph database technologies for managing comprehensive genome-scale networks
I Balaur, A Mazein, M Saqi, A Lysenko, CJ Rawlings, C Auffray
Bioinformatics 33 (7), 1096-1098, 2016
92016
Stratification of asthma phenotypes by airway proteomic signatures
JPR Schofield, D Burg, B Nicholas, F Strazzeri, J Brandsma, D Staykova, ...
Journal of Allergy and Clinical Immunology, 2019
82019
A computational framework for complex disease stratification from multiple large-scale datasets
B De Meulder, D Lefaudeux, AT Bansal, A Mazein, A Chaiboonchoe, ...
BMC Systems Biology 12 (1), 60, 2018
82018
Wiring diagrams in biology: towards the standardized representation of biological information
A Junker, A Sorokin, T Czauderna, F Schreiber, A Mazein
Trends in Biotechnology 30 (11), 555-557, 2012
82012
Regulation and feedback of cholesterol metabolism
A Mazein, S Watterson, H Gibbs, W Hsieh, MB Abdullah, M Blanc, ...
Nature Precedings, 2011
82011
STON: exploring biological pathways using the SBGN standard and graph databases
V Touré, A Mazein, D Waltemath, I Balaur, M Saqi, R Henkel, J Pellet, ...
BMC Bioinformatics 17 (1), 494, 2016
72016
IL-17–high asthma with features of a psoriasis immunophenotype
J Östling, M van Geest, JPR Schofield, Z Jevnikar, S Wilson, J Ward, ...
Journal of Allergy and Clinical Immunology, 2019
42019
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Articles 1–20