The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics J Hardy, DJ Selkoe science 297 (5580), 353-356, 2002 | 16814 | 2002 |
Alzheimer's disease: the amyloid cascade hypothesis JA Hardy, GA Higgins Science 256 (5054), 184-185, 1992 | 8946 | 1992 |
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease A Goate, MC Chartier-Harlin, M Mullan, J Brown, F Crawford, L Fidani, ... Nature 349 (6311), 704-706, 1991 | 6295 | 1991 |
Mild cognitive impairment–beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment B Winblad, K Palmer, M Kivipelto, V Jelic, L Fratiglioni, LO Wahlund, ... Journal of internal medicine 256 (3), 240-246, 2004 | 5724 | 2004 |
The amyloid hypothesis of Alzheimer's disease at 25 years DJ Selkoe, J Hardy EMBO molecular medicine 8 (6), 595-608, 2016 | 5422 | 2016 |
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD AE Renton, E Majounie, A Waite, J Simón-Sánchez, S Rollinson, ... Neuron 72 (2), 257-268, 2011 | 4729 | 2011 |
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 M Hutton, CL Lendon, P Rizzu, M Baker, S Froelich, H Houlden, ... Nature 393 (6686), 702-705, 1998 | 4243 | 1998 |
Amyloid deposition as the central event in the aetiology of Alzheimer's disease J Hardy, D Allsop Trends in pharmacological sciences 12, 383-388, 1991 | 3304 | 1991 |
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease D Harold, R Abraham, P Hollingworth, R Sims, A Gerrish, ML Hamshere, ... Nature genetics 41 (10), 1088-1093, 2009 | 3294 | 2009 |
TREM2 Variants in Alzheimer's Disease R Guerreiro, A Wojtas, J Bras, M Carrasquillo, E Rogaeva, E Majounie, ... New England Journal of Medicine 368 (2), 117-127, 2013 | 3074 | 2013 |
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease P Hollingworth, D Harold, R Sims, A Gerrish, JC Lambert, ... Nature genetics 43 (5), 429-435, 2011 | 2166 | 2011 |
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ... Nature genetics 43 (5), 436-441, 2011 | 2145 | 2011 |
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk IE Jansen, JE Savage, K Watanabe, J Bryois, DM Williams, S Steinberg, ... Nature genetics 51 (3), 404-413, 2019 | 1878 | 2019 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1558 | 2019 |
α‐Synuclein implicated in Parkinson's disease is present in extracellular biological fluids, including human plasma OMA El-Agnaf, SA Salem, KE Paleologou, LJ Cooper, NJ Fullwood, ... The FASEB Journal 17 (13), 1-16, 2003 | 685 | 2003 |
Polymeric materials based on silk proteins JG Hardy, LM Römer, TR Scheibel Polymer 49 (20), 4309-4327, 2008 | 608 | 2008 |
A conserved spider silk domain acts as a molecular switch that controls fibre assembly F Hagn, L Eisoldt, JG Hardy, C Vendrely, M Coles, T Scheibel, H Kessler Nature 465 (7295), 239-242, 2010 | 466 | 2010 |
Composite materials based on silk proteins JG Hardy, TR Scheibel Progress in Polymer Science 35 (9), 1093-1115, 2010 | 396 | 2010 |
Biomimetic conducting polymer-based tissue scaffolds JG Hardy, JY Lee, CE Schmidt Current opinion in biotechnology 24 (5), 847-854, 2013 | 284 | 2013 |
Bioactive gyroid scaffolds formed by sacrificial templating of nanocellulose and nanochitin hydrogels as instructive platforms for biomimetic tissue engineering JG Torres-Rendon, T Femmer, L De Laporte, T Tigges, K Rahimi, ... Advanced materials 27 (19), 2989-2995, 2015 | 239 | 2015 |