Thomas Schwarzl
Thomas Schwarzl
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A brave new world of RNA-binding proteins
MW Hentze, A Castello, T Schwarzl, T Preiss
Nature reviews Molecular cell biology 19 (5), 327, 2018
The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs
BM Beckmann, R Horos, B Fischer, A Castello, K Eichelbaum, ...
Nature communications 6 (1), 1-9, 2015
Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcription
J Rauch, E O'Neill, B Mack, C Matthias, M Munz, W Kolch, O Gires
Cancer research 70 (4), 1679-1688, 2010
The human RNA-binding proteome and its dynamics during translational arrest
J Trendel, T Schwarzl, R Horos, A Prakash, A Bateman, MW Hentze, ...
Cell 176 (1-2), 391-403. e19, 2019
GeneSigDB—a curated database of gene expression signatures
AC Culhane, T Schwarzl, R Sultana, KC Picard, SC Picard, TH Lu, ...
Nucleic acids research 38 (suppl_1), D716-D725, 2010
FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation
J Popow, AM Alleaume, T Curk, T Schwarzl, S Sauer, MW Hentze
RNA 21 (11), 1873-1884, 2015
GSK3 inhibitors regulate MYCN mRNA levels and reduce neuroblastoma cell viability through multiple mechanisms, including p53 and Wnt signaling
DJ Duffy, A Krstic, T Schwarzl, DG Higgins, W Kolch
Molecular cancer therapeutics 13 (2), 454-467, 2014
Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture
JI Perez-Perri, B Rogell, T Schwarzl, F Stein, Y Zhou, M Rettel, A Brosig, ...
Nature communications 9 (1), 1-13, 2018
The small non-coding vault RNA1-1 acts as a riboregulator of autophagy
R Horos, M Büscher, R Kleinendorst, AM Alleaume, AK Tarafder, ...
Cell 176 (5), 1054-1067. e12, 2019
Exon junction complexes show a distributional bias toward alternatively spliced mRNAs and against mRNAs coding for ribosomal proteins
C Hauer, J Sieber, T Schwarzl, I Hollerer, T Curk, AM Alleaume, ...
Cell reports 16 (6), 1588-1603, 2016
Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma
DJ Duffy, A Krstic, M Halasz, T Schwarzl, D Fey, K Iljin, JP Mehta, K Killick, ...
Oncotarget 6 (41), 43182, 2015
Improved binding site assignment by high-resolution mapping of RNA-protein interactions using iCLIP
C Hauer, T Curk, S Anders, T Schwarzl, AM Alleaume, J Sieber, I Hollerer, ...
Nature communications 6, 7921, 2015
Retinoic acid and TGF-β signalling cooperate to overcome MYCN-induced retinoid resistance
DJ Duffy, A Krstic, M Halasz, T Schwarzl, A Konietzny, K Iljin, DG Higgins, ...
Genome medicine 9 (1), 1-22, 2017
Wnt signalling is a bi-directional vulnerability of cancer cells
DJ Duffy, A Krstic, T Schwarzl, M Halasz, K Iljin, D Fey, B Haley, J Whilde, ...
Oncotarget 7 (37), 60310, 2016
Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner
SF Fitzpatrick, Z Fábián, B Schaible, CR Lenihan, T Schwarzl, ...
Biochemical and biophysical research communications 474 (3), 579-586, 2016
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas
D Dreidax, S Bannert, KO Henrich, C Schröder, S Bender, CC Oakes, ...
Human molecular genetics 23 (25), 6826-6837, 2014
An integrated global analysis of compartmentalized HRAS signaling
T Santra, A Herrero, J Rodriguez, A Von Kriegsheim, LF Iglesias-Martinez, ...
Cell reports 26 (11), 3100-3115. e7, 2019
The RNA-binding protein YBX3 controls amino acid levels by regulating SLC mRNA abundance
A Cooke, T Schwarzl, I Huppertz, G Kramer, P Mantas, AM Alleaume, ...
Cell reports 27 (11), 3097-3106. e5, 2019
Measuring transcription rate changes via time-course 4-thiouridine pulse-labelling improves transcriptional target identification
T Schwarzl, DG Higgins, W Kolch, DJ Duffy
Journal of molecular biology 427 (21), 3368-3374, 2015
Plasticity of nuclear and cytoplasmic stress responses of RNA-binding proteins
M Backlund, F Stein, M Rettel, T Schwarzl, JI Perez-Perri, A Brosig, ...
Nucleic acids research 48 (9), 4725-4740, 2020
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