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Kris White
Kris White
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
43962020
The global phosphorylation landscape of SARS-CoV-2 infection
M Bouhaddou, D Memon, B Meyer, KM White, VV Rezelj, MC Marrero, ...
Cell 182 (3), 685-712. e19, 2020
8712020
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, L Pache, ...
Nature 586 (7827), 113-119, 2020
7292020
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
6202020
SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling
L Miorin, T Kehrer, MT Sanchez-Aparicio, K Zhang, P Cohen, RS Patel, ...
Proceedings of the National Academy of Sciences 117 (45), 28344-28354, 2020
4782020
Transcription elongation can affect genome 3D structure
S Heinz, L Texari, MGB Hayes, M Urbanowski, MW Chang, N Givarkes, ...
Cell 174 (6), 1522-1536. e22, 2018
3782018
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
3732020
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A
KM White, R Rosales, S Yildiz, T Kehrer, L Miorin, E Moreno, S Jangra, ...
Science 371 (6532), 926-931, 2021
2992021
Evolution of enhanced innate immune evasion by SARS-CoV-2
LG Thorne, M Bouhaddou, AK Reuschl, L Zuliani-Alvarez, B Polacco, ...
Nature 602 (7897), 487-495, 2022
2752022
Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19
B Boras, RM Jones, BJ Anson, D Arenson, L Aschenbrenner, ...
Nature communications 12 (1), 6055, 2021
2052021
An in vitro microneutralization assay for SARS‐CoV‐2 serology and drug screening
F Amanat, KM White, L Miorin, S Strohmeier, M McMahon, P Meade, ...
Current protocols in microbiology 58 (1), e108, 2020
1752020
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ...
Cell Stem Cell 29 (2), 217-231. e8, 2022
1742022
Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2
TA Tummino, VV Rezelj, B Fischer, A Fischer, MJ O’meara, B Monel, ...
Science 373 (6554), 541-547, 2021
1642021
COVID-19: famotidine, histamine, mast cells, and mechanisms
RW Malone, P Tisdall, P Fremont-Smith, Y Liu, XP Huang, KM White, ...
Frontiers in Pharmacology 12, 633680, 2021
1522021
Varicella-zoster virus immediate-early protein 62 blocks interferon regulatory factor 3 (IRF3) phosphorylation at key serine residues: a novel mechanism of IRF3 inhibition …
N Sen, M Sommer, X Che, K White, WT Ruyechan, AM Arvin
Journal of virology 84 (18), 9240-9253, 2010
1022010
Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication
SK Kuss-Duerkop, J Wang, I Mena, K White, G Metreveli, R Sakthivel, ...
PLoS pathogens 13 (9), e1006635, 2017
932017
A large-scale drug repositioning survey for SARS-CoV-2 antivirals
L Riva, S Yuan, X Yin, L Martin-Sancho, N Matsunaga, ...
BioRxiv, 2020.04. 16.044016, 2020
912020
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ...
Cell 184 (10), 2618-2632. e17, 2021
842021
An ultra-potent synthetic nanobody neutralizes SARS-CoV-2 by locking Spike into an inactive conformation
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
BioRxiv, 2020
602020
Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture
K Bafna, K White, B Harish, R Rosales, TA Ramelot, TB Acton, E Moreno, ...
Cell reports 35 (7), 2021
592021
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