Philip Fowler
TitleCited byYear
Crystal structure of a prokaryotic homologue of the mammalian oligopeptide–proton symporters, PepT1 and PepT2
S Newstead, D Drew, AD Cameron, VLG Postis, X Xia, PW Fowler, ...
The EMBO journal 30 (2), 417-426, 2010
2382010
Alternating access mechanism in the POT family of oligopeptide transporters
N Solcan, J Kwok, PW Fowler, AD Cameron, D Drew, S Iwata, ...
The EMBO journal 31 (16), 3411-3421, 2012
1672012
Modelling biological complexity: a physical scientist's perspective
PV Coveney, PW Fowler
Journal of The Royal Society Interface 2 (4), 267-280, 2005
1052005
Helix− Helix Interactions in Membrane Proteins: Coarse-Grained Simulations of Glycophorin A Helix Dimerization†
E Psachoulia, PW Fowler, PJ Bond, MSP Sansom
Biochemistry 47 (40), 10503-10512, 2008
892008
The selectivity of K+ ion channels: testing the hypotheses
PW Fowler, K Tai, MSP Sansom
Biophysical journal 95 (11), 5062-5072, 2008
702008
H bonding at the helix-bundle crossing controls gating in Kir potassium channels
M Rapedius, PW Fowler, L Shang, MSP Sansom, SJ Tucker, T Baukrowitz
Neuron 55 (4), 602-614, 2007
612007
Nothing to sneeze at: a dynamic and integrative computational model of an Influenza A virion
T Reddy, D Shorthouse, DL Parton, E Jefferys, PW Fowler, M Chavent, ...
Structure 23 (3), 584-597, 2015
602015
The pore of voltage-gated potassium ion channels is strained when closed
PW Fowler, MSP Sansom
Nature Communications 4, 1872, 2013
522013
Insights into how nucleotide-binding domains power ABC transport
S Newstead, PW Fowler, P Bilton, EP Carpenter, PJ Sadler, ...
Structure 17 (9), 1213-1222, 2009
492009
Gating Topology of the Proton-Coupled Oligopeptide Symporters
PW Fowler, M Orwick-Rydmark, S Radestock, N Solcan, PM Dijkman, ...
Structure 23 (2), 290-301, 2015
462015
Monotopic enzymes and lipid bilayers: a comparative study
PW Fowler, K Balali-Mood, S Deol, PV Coveney, MSP Sansom
Biochemistry 46 (11), 3108-3115, 2007
422007
Flexible Gates Generate Occluded Intermediates in the Transport Cycle of LacY
LS Stelzl, PW Fowler, MSP Sansom, O Beckstein
Journal of Molecular Biology 426 (3), 735-751, 2014
412014
Control of pH and PIP2 gating in heteromeric Kir4. 1/Kir5. 1 channels by H-bonding at the helix-bundle crossing
M Rapedius, JJ Paynter, P Fowler, L Shang, M Sansom, SJ Tucker, ...
Channels 1 (5), 327-330, 2007
342007
Alchembed: A Computational Method for Incorporating Multiple Proteins into Complex Lipid Geometries
E Jefferys, ZA Sands, J Shi, MSP Sansom, PW Fowler
Journal of chemical theory and computation 11 (6), 2743-2754, 2015
312015
Lattice-gas simulations of ternary amphiphilic fluid flow in porous media
PV Coveney, JB Maillet, JL Wilson, PW Fowler, O Al-Mushadani, ...
International Journal of Modern Physics C 9 (08), 1479-1490, 1998
281998
Molecular modeling and simulation studies of ion channel structures, dynamics and mechanisms
K Tai, P Fowler, Y Mokrab, P Stansfeld, MSP Sansom
Methods in cell biology 90, 233-265, 2008
272008
Energetics of Multi-Ion Conduction Pathways in Potassium Ion Channels
PW Fowler, E Abad, O Beckstein, MSP Sansom
Journal of Chemical Theory and Computation 9 (11), 5176-5189, 2013
262013
Grid-based steered thermodynamic integration accelerates the calculation of binding free energies
PW Fowler, S Jha, PV Coveney
Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2005
252005
Membrane stiffness is modified by integral membrane proteins
PW Fowler, J Hélie, A Duncan, M Chavent, H Koldsø, MSP Sansom
Soft Matter 12 (37), 7792-7803, 2016
242016
A computational protocol for the integration of the monotopic protein prostaglandin H2 synthase into a phospholipid bilayer
PW Fowler, PV Coveney
Biophysical journal 91 (2), 401-410, 2006
212006
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Articles 1–20