Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands SC Jin, J Homsy, S Zaidi, Q Lu, S Morton, SR DePalma, X Zeng, H Qi, ... Nature genetics 49 (11), 1593-1601, 2017 | 814 | 2017 |
Crystal structure of the potassium form of an Oxytricha nova G-quadruplex S Haider, GN Parkinson, S Neidle Journal of Molecular Biology 320 (2), 189-200, 2002 | 410 | 2002 |
Structure of a G-quadruplex–ligand complex SM Haider, GN Parkinson, S Neidle Journal of molecular biology 326 (1), 117-125, 2003 | 376 | 2003 |
Blocking FSH induces thermogenic adipose tissue and reduces body fat P Liu, Y Ji, T Yuen, E Rendina-Ruedy, VE DeMambro, S Dhawan, ... Nature 546 (7656), 107-112, 2017 | 336 | 2017 |
Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study DJH Moss, AF Pardiņas, D Langbehn, K Lo, BR Leavitt, R Roos, A Durr, ... The Lancet Neurology 16 (9), 701-711, 2017 | 328 | 2017 |
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex GW Collie, SM Haider, S Neidle, GN Parkinson Nucleic acids research 38 (16), 5569-5580, 2010 | 280 | 2010 |
Functional analysis of a structural model of the ATP‐binding site of the KATP channel Kir6. 2 subunit JF Antcliff, S Haider, P Proks, MSP Sansom, FM Ashcroft The EMBO journal 24 (2), 229-239, 2005 | 252 | 2005 |
Molecular dynamics and principal components analysis of human telomeric quadruplex multimers S Haider, GN Parkinson, S Neidle Biophysical journal 95 (1), 296-311, 2008 | 238 | 2008 |
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 198 | 2017 |
Sequence occurrence and structural uniqueness of a G-quadruplex in the human c-kit promoter AK Todd, SM Haider, GN Parkinson, S Neidle Nucleic acids research 35 (17), 5799-5808, 2007 | 175 | 2007 |
Targeting human gastrointestinal stromal tumor cells with a quadruplex-binding small molecule M Gunaratnam, S Swank, SM Haider, K Galesa, AP Reszka, M Beltran, ... Journal of medicinal chemistry 52 (12), 3774-3783, 2009 | 167 | 2009 |
Tri-and tetra-substituted naphthalene diimides as potent G-quadruplex ligands F Cuenca, O Greciano, M Gunaratnam, S Haider, D Munnur, R Nanjunda, ... Bioorganic & medicinal chemistry letters 18 (5), 1668-1673, 2008 | 166 | 2008 |
Structure–phenotype correlations of human CYP21A2 mutations in congenital adrenal hyperplasia S Haider, B Islam, V D’Atri, M Sgobba, C Poojari, L Sun, T Yuen, M Zaidi, ... Proceedings of the National Academy of Sciences 110 (7), 2605-2610, 2013 | 160 | 2013 |
A structural analysis of G-quadruplex/ligand interactions SM Haider, S Neidle, GN Parkinson Biochimie 93 (8), 1239-1251, 2011 | 153 | 2011 |
Mutations disrupting neuritogenesis genes confer risk for cerebral palsy SC Jin, SA Lewis, S Bakhtiari, X Zeng, MC Sierant, S Shetty, SM Nordlie, ... Nature genetics 52 (10), 1046-1056, 2020 | 148 | 2020 |
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule C Marchetti, KG Zyner, SA Ohnmacht, M Robson, SM Haider, JP Morton, ... Journal of medicinal chemistry 61 (6), 2500-2517, 2018 | 145 | 2018 |
De novo mutation in genes regulating neural stem cell fate in human congenital hydrocephalus CG Furey, J Choi, SC Jin, X Zeng, AT Timberlake, C Nelson-Williams, ... Neuron 99 (2), 302-314. e4, 2018 | 143 | 2018 |
A G-quadruplex-binding compound showing anti-tumour activity in an in vivo model for pancreatic cancer SA Ohnmacht, C Marchetti, M Gunaratnam, RJ Besser, SM Haider, ... Scientific reports 5 (1), 11385, 2015 | 135 | 2015 |
Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus SC Jin, W Dong, AJ Kundishora, S Panchagnula, A Moreno-De-Luca, ... Nature medicine 26 (11), 1754-1765, 2020 | 131 | 2020 |
Clinical, genetic, and structural basis of congenital adrenal hyperplasia due to 11β-hydroxylase deficiency A Khattab, S Haider, A Kumar, S Dhawan, D Alam, R Romero, J Burns, ... Proceedings of the National Academy of Sciences 114 (10), E1933-E1940, 2017 | 130 | 2017 |