Olivier Cloarec
Olivier Cloarec
Principal Research Scientist, Sartorius Corporate Research
Verified email at
Cited by
Cited by
OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification
M Bylesjö, M Rantalainen, O Cloarec, JK Nicholson, E Holmes, J Trygg
Journal of Chemometrics: A Journal of the Chemometrics Society 20 (8‐10 …, 2006
Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice
ME Dumas, RH Barton, A Toye, O Cloarec, C Blancher, A Rothwell, ...
Proceedings of the national academy of sciences 103 (33), 12511-12516, 2006
Pharmaco-metabonomic phenotyping and personalized drug treatment
T Andrew Clayton, JC Lindon, O Cloarec, H Antti, C Charuel, G Hanton, ...
Nature 440 (7087), 1073-1077, 2006
Statistical Total Correlation Spectroscopy:  An Exploratory Approach for Latent Biomarker Identification from Metabolic 1H NMR Data Sets
O Cloarec, ME Dumas, A Craig, RH Barton, J Trygg, J Hudson, ...
Analytical chemistry 77 (5), 1282-1289, 2005
Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR …
O Cloarec, ME Dumas, J Trygg, A Craig, RH Barton, JC Lindon, ...
Analytical chemistry 77 (2), 517-526, 2005
Scaling and normalization effects in NMR spectroscopic metabonomic data sets
A Craig, O Cloarec, E Holmes, JK Nicholson, JC Lindon
Analytical chemistry 78 (7), 2262-2267, 2006
A top‐down systems biology view of microbiome‐mammalian metabolic interactions in a mouse model
FPJ Martin, ME Dumas, Y Wang, C Legido‐Quigley, IKS Yap, H Tang, ...
Molecular systems biology 3 (1), 112, 2007
Susceptibility of human metabolic phenotypes to dietary modulation
C Stella, B Beckwith-Hall, O Cloarec, E Holmes, JC Lindon, J Powell, ...
Journal of proteome research 5 (10), 2780-2788, 2006
Colonization-induced host-gut microbial metabolic interaction
SP Claus, SL Ellero, B Berger, L Krause, A Bruttin, J Molina, A Paris, ...
MBio 2 (2), 10.1128/mbio. 00271-10, 2011
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes
SP Claus, TM Tsang, Y Wang, O Cloarec, E Skordi, FP Martin, S Rezzi, ...
Molecular systems biology 4 (1), 219, 2008
Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification
Y Wang, E Holmes, JK Nicholson, O Cloarec, J Chollet, M Tanner, ...
Proceedings of the National Academy of Sciences 101 (34), 12676-12681, 2004
Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function
F Dutheil, S Dauchy, M Diry, V Sazdovitch, O Cloarec, L Mellottée, ...
Drug Metabolism and Disposition 37 (7), 1528-1538, 2009
Statistically integrated metabonomic− proteomic studies on a human prostate cancer xenograft model in mice
M Rantalainen, O Cloarec, O Beckonert, ID Wilson, D Jackson, R Tonge, ...
Journal of proteome research 5 (10), 2642-2655, 2006
Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data …
SJ Bruce, P Jonsson, H Antti, O Cloarec, J Trygg, SL Marklund, T Moritz
Analytical Biochemistry 372 (2), 237-249, 2008
Robust data processing and normalization strategy for MALDI mass spectrometric imaging
JM Fonville, C Carter, O Cloarec, JK Nicholson, JC Lindon, J Bunch, ...
Analytical chemistry 84 (3), 1310-1319, 2012
Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy
E Holmes, RL Loo, O Cloarec, M Coen, H Tang, E Maibaum, S Bruce, ...
Analytical chemistry 79 (7), 2629-2640, 2007
Development and application of ultra-performance liquid chromatography-TOF MS for precision large scale urinary metabolic phenotyping
MR Lewis, JTM Pearce, K Spagou, M Green, AC Dona, AHY Yuen, ...
Analytical chemistry 88 (18), 9004-9013, 2016
1H HR-MAS NMR Spectroscopy of Tumor-Induced Local Metabolic “Field-Effects” Enables Colorectal Cancer Staging and Prognostication
B Jiménez, R Mirnezami, J Kinross, O Cloarec, HC Keun, E Holmes, ...
Journal of proteome research 12 (2), 959-968, 2013
Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects
R Mirnezami, K Spagou, PA Vorkas, MR Lewis, J Kinross, E Want, ...
Molecular oncology 8 (1), 39-49, 2014
Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice
AA Toye, ME Dumas, C Blancher, AR Rothwell, JF Fearnside, SP Wilder, ...
Diabetologia 50, 1867-1879, 2007
The system can't perform the operation now. Try again later.
Articles 1–20