| Mesenchymal stem cells are recruited and activated into carcinoma-associated fibroblasts by prostate cancer microenvironment-derived TGF-β1 P Barcellos-de-Souza, G Comito, C Pons-Segura, ML Taddei, V Gori, ... Stem cells 34 (10), 2536-2547, 2016 | 192 | 2016 |
| Matrix metalloproteinase 12–dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis S D'Alessio, G Fibbi, M Cinelli, S Guiducci, A Del Rosso, F Margheri, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2004 | 152 | 2004 |
| The urokinase receptor system, a key regulator at the intersection between inflammation, immunity, and coagulation MD Rosso, F Margheri, S Serratì, A Chillà, A Laurenzana, G Fibbi Current pharmaceutical design 17 (19), 1924-1943, 2011 | 115 | 2011 |
| The acidic microenvironment as a possible niche of dormant tumor cells S Peppicelli, E Andreucci, J Ruzzolini, A Laurenzana, F Margheri, G Fibbi, ... Cellular and molecular life sciences 74, 2761-2771, 2017 | 104 | 2017 |
| Overexpression of the transmembrane carbonic anhydrase isoforms IX and XII in the inflamed synovium F Margheri, M Ceruso, F Carta, A Laurenzana, L Maggi, S Lazzeri, ... Journal of enzyme inhibition and medicinal chemistry 31 (sup4), 60-63, 2016 | 95 | 2016 |
| The plasminogen activation system in inflammation M Del Rosso, G Fibbi, M Pucci, F Margheri, S Serrati Front Biosci 13 (13), 4667-4686, 2008 | 88 | 2008 |
| Effects of blocking urokinase receptor signaling by antisense oligonucleotides in a mouse model of experimental prostate cancer bone metastases F Margheri, S D'alessio, S Serrati, M Pucci, F Annunziato, L Cosmi, ... Gene Therapy 12 (8), 702-714, 2005 | 88 | 2005 |
| Endothelial progenitor cell–dependent angiogenesis requires localization of the full-length form of uPAR in caveolae F Margheri, A Chilla, A Laurenzana, S Serratì, B Mazzanti, R Saccardi, ... Blood, The Journal of the American Society of Hematology 118 (13), 3743-3755, 2011 | 82 | 2011 |
| Domain 1 of the urokinase‐type plasminogen activator receptor is required for its morphologic and functional, β2 integrin–mediated connection with actin cytoskeleton in human … F Margheri, M Manetti, S Serratì, D Nosi, M Pucci, M Matucci‐Cerinic, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2006 | 79 | 2006 |
| The antiangiogenic tissue kallikrein pattern of endothelial cells in systemic sclerosis B Giusti, S Serratì, F Margheri, L Papucci, L Rossi, F Poggi, A Magi, ... Arthritis & Rheumatism 52 (11), 3618-3628, 2005 | 76 | 2005 |
| TGFβ1 antagonistic peptides inhibit TGFβ1-dependent angiogenesis S Serratì, F Margheri, M Pucci, AR Cantelmo, R Cammarota, J Dotor, ... Biochemical pharmacology 77 (5), 813-825, 2009 | 71 | 2009 |
| A model of anti-angiogenesis: differential transcriptosome profiling of microvascular endothelial cells from diffuse systemic sclerosis patients B Giusti, G Fibbi, F Margheri, S Serratì, L Rossi, F Poggi, I Lapini, A Magi, ... Arthritis research & therapy 8, 1-17, 2006 | 63 | 2006 |
| Antisense oligodeoxynucleotides for urokinase‐plasminogen activator receptor have anti‐invasive and anti‐proliferative effects in vitro and inhibit spontaneous metastases of … S D'Alessio, F Margheri, M Pucci, A Del Rosso, BP Monia, M Bologna, ... International journal of cancer 110 (1), 125-133, 2004 | 60 | 2004 |
| Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation S Peppicelli, A Toti, E Giannoni, F Bianchini, F Margheri, M Del Rosso, ... Cell Cycle 15 (14), 1908-1918, 2016 | 58 | 2016 |
| Modulation of the angiogenic phenotype of normal and systemic sclerosis endothelial cells by gain–loss of function of pentraxin 3 and matrix metalloproteinase 12 F Margheri, S Serratì, A Lapucci, A Chilla, L Bazzichi, S Bombardieri, ... Arthritis & Rheumatism 62 (8), 2488-2498, 2010 | 58 | 2010 |
| Inhibition of uPAR-TGFβ crosstalk blocks MSC-dependent EMT in melanoma cells A Laurenzana, A Biagioni, F Bianchini, S Peppicelli, A Chillà, F Margheri, ... Journal of molecular medicine 93, 783-794, 2015 | 57 | 2015 |
| The receptor for urokinase-plasminogen activator (uPAR) controls plasticity of cancer cell movement in mesenchymal and amoeboid migration style F Margheri, C Luciani, ML Taddei, E Giannoni, A Laurenzana, A Biagioni, ... Oncotarget 5 (6), 1538, 2014 | 57 | 2014 |
| Systemic sclerosis fibroblasts inhibit in vitro angiogenesis by MMP‐12‐dependent cleavage of the endothelial cell urokinase receptor S Serrati, M Cinelli, F Margheri, S Guiducci, A Del Rosso, M Pucci, G Fibbi, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2006 | 52 | 2006 |
| Systemic sclerosis endothelial cells recruit and activate dermal fibroblasts by induction of a connective tissue growth factor (CCN2)/transforming growth factor β–dependent … S Serratì, A Chillà, A Laurenzana, F Margheri, E Giannoni, L Magnelli, ... Arthritis & Rheumatism 65 (1), 258-269, 2013 | 51 | 2013 |
| Endothelial cells and normal breast epithelial cells enhance invasion of breast carcinoma cells by CXCR‐4‐dependent up‐regulation of urokinase‐type plasminogen activator … S Serrati, F Margheri, G Fibbi, G Di Cara, L Minafra, I Pucci‐Minafra, ... The Journal of Pathology: A Journal of the Pathological Society of Great …, 2008 | 51 | 2008 |
