| Approaches to altering particle distributions in cryo-electron microscopy sample preparation I Drulyte, RM Johnson, EL Hesketh, DL Hurdiss, CA Scarff, SA Porav, ... Acta Crystallographica Section D: Structural Biology 74 (6), 560-571, 2018 | 152 | 2018 |
| In silico fragment-based design identifies subfamily B1 metallo-β-lactamase inhibitors R Cain, J Brem, D Zollman, MA McDonough, RM Johnson, J Spencer, ... Journal of Medicinal Chemistry 61 (3), 1255-1260, 2018 | 48 | 2018 |
| Evolving cryo-EM structural approaches for GPCR drug discovery X Zhang, RM Johnson, I Drulyte, L Yu, A Kotecha, R Danev, D Wootten, ... Structure 29 (9), 963-974. e6, 2021 | 38 | 2021 |
| Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site DJ Wright, KJ Simmons, RM Johnson, DJ Beech, SP Muench, RS Bon Communications Biology 3 (1), 704, 2020 | 38 | 2020 |
| A structural basis for amylin receptor phenotype J Cao, MJ Belousoff, YL Liang, RM Johnson, TM Josephs, MM Fletcher, ... Science 375 (6587), eabm9609, 2022 | 34 | 2022 |
| Cryo-EM Structure and Molecular Dynamics Analysis of the Fluoroquinolone Resistant Mutant of the AcrB Transporter from Salmonella RM Johnson, C Fais, M Parmar, H Cheruvara, RL Marshall, SJ Hesketh, ... Microorganisms 8 (6), 943, 2020 | 34 | 2020 |
| Potent tetrahydroquinolone eliminates apicomplexan parasites MJ McPhillie, Y Zhou, MR Hickman, JA Gordon, CR Weber, Q Li, PJ Lee, ... Frontiers in cellular and infection microbiology 10, 203, 2020 | 27 | 2020 |
| X-ray and cryo-EM structures of inhibitor-bound cytochrome bc1 complexes for structure-based drug discovery K Amporndanai, RM Johnson, PM O'Neill, CWG Fishwick, AH Jamson, ... IUCrJ 5 (2), 200-210, 2018 | 27 | 2018 |
| Structure-based identification and characterization of inhibitors of the epilepsy-associated KNa1. 1 (KCNT1) potassium channel BA Cole, RM Johnson, H Dejakaisaya, N Pilati, CWG Fishwick, ... IScience 23 (5), 2020 | 26 | 2020 |
| Membranes under the magnetic lens: a dive into the diverse world of membrane protein structures using Cryo-EM SJ Piper, RM Johnson, D Wootten, PM Sexton Chemical reviews 122 (17), 13989-14017, 2022 | 22 | 2022 |
| Cryo-EM structure of the dual incretin receptor agonist, peptide-19, in complex with the glucagon-like peptide-1 receptor RM Johnson, X Zhang, SJ Piper, TJ Nettleton, TH Vandekolk, ... Biochemical and Biophysical Research Communications 578, 84-90, 2021 | 17 | 2021 |
| LAT1 (SLC7A5) and CD98hc (SLC3A2) complex dynamics revealed by single-particle cryo-EM GN Chiduza, RM Johnson, GSA Wright, SV Antonyuk, SP Muench, ... Acta Crystallographica Section D: Structural Biology 75 (7), 660-669, 2019 | 17 | 2019 |
| Dimeric structures of quinol-dependent nitric oxide reductases (qNORs) revealed by cryo–electron microscopy CC Gopalasingam, RM Johnson, GN Chiduza, T Tosha, M Yamamoto, ... Science Advances 5 (8), eaax1803, 2019 | 16 | 2019 |
| New insights into the structure and function of class B1 GPCRs BP Cary, X Zhang, J Cao, RM Johnson, SJ Piper, EJ Gerrard, D Wootten, ... Endocrine reviews 44 (3), 492-517, 2023 | 15 | 2023 |
| The active form of quinol-dependent nitric oxide reductase from Neisseria meningitidis is a dimer MAM Jamali, CC Gopalasingam, RM Johnson, T Tosha, K Muramoto, ... IUCrJ 7 (3), 404-415, 2020 | 11 | 2020 |
| The potential use of single-particle electron microscopy as a tool for structure-based inhibitor design S Rawson, MJ McPhillie, RM Johnson, CWG Fishwick, SP Muench Acta Crystallographica Section D: Structural Biology 73 (6), 534-540, 2017 | 11 | 2017 |
| Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial O Abani, A Abbas, F Abbas, J Abbas, K Abbas, M Abbas, S Abbasi, ... The Lancet Diabetes & Endocrinology 11 (12), 905-914, 2023 | 6 | 2023 |
| Structure-based identification and characterization of inhibitors of the epilepsy-associated KNa1. 1 (KCNT1) potassium channel. iScience 23: 101100 BA Cole, RM Johnson, H Dejakaisaya, N Pilati, CWG Fishwick, ... J. ISCI, 2020 | 6 | 2020 |
| Cryo-EM structures of human TRPC5 reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site DJ Wright, KJ Simmons, RM Johnson, DJ Beech, SP Muench, RS Bon bioRxiv, 2020.04. 17.047456, 2020 | 4 | 2020 |
| Emerging role of electron microscopy in drug discovery RM Johnson, AJ Higgins, SP Muench Trends in Biochemical Sciences 44 (10), 897-898, 2019 | 4 | 2019 |
