| Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses MG Joyce, AK Wheatley, PV Thomas, GY Chuang, C Soto, RT Bailer, ... Cell 166 (3), 609-623, 2016 | 300 | 2016 |
| Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ... doi: https://doi.org/10.1101/306282, 2018 | 275 | 2018 |
| Quantification of the impact of the HIV-1-glycan shield on antibody elicitation T Zhou, NA Doria-Rose, C Cheng, GBE Stewart-Jones, GY Chuang, ... Cell reports 19 (4), 719-732, 2017 | 179 | 2017 |
| Amprenavir complexes with HIV‐1 protease and its drug‐resistant mutants altering hydrophobic clusters CH Shen, YF Wang, AY Kovalevsky, RW Harrison, IT Weber The FEBS journal 277 (18), 3699-3714, 2010 | 149 | 2010 |
| HIV-1 protease with 20 mutations exhibits extreme resistance to clinical inhibitors through coordinated structural rearrangements J Agniswamy, CH Shen, A Aniana, JM Sayer, JM Louis, IT Weber Biochemistry 51 (13), 2819-2828, 2012 | 106 | 2012 |
| Antibody lineages with vaccine-induced antigen-binding hotspots develop broad HIV neutralization R Kong, H Duan, Z Sheng, K Xu, P Acharya, X Chen, C Cheng, ... Cell 178 (3), 567-584. e19, 2019 | 104 | 2019 |
| PaRSnIP: sequence-based protein solubility prediction using gradient boosting machine R Rawi, R Mall, K Kunji, CH Shen, PD Kwong, GY Chuang Bioinformatics 34 (7), 1092-1098, 2018 | 89 | 2018 |
| Longitudinal analysis reveals early development of three MPER-directed neutralizing antibody lineages from an HIV-1-infected individual SJ Krebs, YD Kwon, CA Schramm, WH Law, G Donofrio, KH Zhou, S Gift, ... Immunity 50 (3), 677-691. e13, 2019 | 78 | 2019 |
| A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ... Immunity 48 (3), 500-513. e6, 2018 | 77 | 2018 |
| Role of humoral immunity against hepatitis B virus core antigen in the pathogenesis of acute liver failure Z Chen, G Diaz, T Pollicino, H Zhao, RE Engle, P Schuck, CH Shen, ... Proceedings of the National Academy of Sciences 115 (48), E11369-E11378, 2018 | 74 | 2018 |
| Structural survey of broadly neutralizing antibodies targeting the HIV-1 Env trimer delineates epitope categories and characteristics of recognition GY Chuang, J Zhou, P Acharya, R Rawi, CH Shen, Z Sheng, B Zhang, ... Structure 27 (1), 196-206. e6, 2019 | 72 | 2019 |
| Long‐range electrostatics‐induced two‐proton transfer captured by neutron crystallography in an enzyme catalytic site O Gerlits, T Wymore, A Das, CH Shen, JM Parks, JC Smith, KL Weiss, ... Angewandte Chemie 128 (16), 5008-5011, 2016 | 60 | 2016 |
| Structure of super-potent antibody CAP256-VRC26. 25 in complex with HIV-1 envelope reveals a combined mode of trimer-apex recognition J Gorman, GY Chuang, YT Lai, CH Shen, JC Boyington, A Druz, H Geng, ... Cell reports 31 (1), 2020 | 51 | 2020 |
| Paired heavy-and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses BB Banach, G Cerutti, AS Fahad, CH Shen, MO De Souza, PS Katsamba, ... Cell Reports 37 (1), 2021 | 46 | 2021 |
| Extreme multidrug resistant HIV-1 protease with 20 mutations is resistant to novel protease inhibitors with P1′-pyrrolidinone or P2-tris-tetrahydrofuran J Agniswamy, CH Shen, YF Wang, AK Ghosh, KV Rao, CX Xu, JM Sayer, ... Journal of medicinal chemistry 56 (10), 4017-4027, 2013 | 44 | 2013 |
| Vaccination with prefusion-stabilized respiratory syncytial virus fusion protein induces genetically and antigenically diverse antibody responses M Mukhamedova, D Wrapp, CH Shen, MSA Gilman, TJ Ruckwardt, ... Immunity 54 (4), 769-780. e6, 2021 | 40 | 2021 |
| Automated prediction of HIV drug resistance from genotype data RWHITW ChenHsiang Shen, Xiaxia Yu BMC Bioinformatics 17 (Suppl 8), 278, 2016 | 37* | 2016 |
| Novel P2 Tris-tetrahydrofuran Group in Antiviral Compound 1 (GRL-0519) Fills the S2 Binding Pocket of Selected Mutants of HIV-1 Protease H Zhang, YF Wang, CH Shen, J Agniswamy, KV Rao, CX Xu, AK Ghosh, ... Journal of medicinal chemistry 56 (3), 1074-1083, 2013 | 36 | 2013 |
| Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with> 50% breadth X Chen, T Zhou, SD Schmidt, H Duan, C Cheng, GY Chuang, Y Gu, ... Immunity 54 (2), 324-339. e8, 2021 | 32 | 2021 |
| Accurate prediction for antibody resistance of clinical HIV-1 isolates R Rawi, R Mall, CH Shen, SK Farney, A Shiakolas, J Zhou, H Bensmail, ... Scientific reports 9 (1), 14696, 2019 | 32 | 2019 |
Irene WeberGeorgia State UniversityVerified email at gsu.edu
