Inhibition of TRPM8 channels reduces pain in the cold pressor test in humans WJ Winchester, K Gore, S Glatt, W Petit, JC Gardiner, K Conlon, ... Journal of Pharmacology and Experimental Therapeutics 351 (2), 259-269, 2014 | 96 | 2014 |
Inhalation by design: novel ultra-long-acting β2-adrenoreceptor agonists for inhaled once-daily treatment of asthma and chronic obstructive pulmonary disease that utilize a … PA Glossop, CAL Lane, DA Price, ME Bunnage, RA Lewthwaite, K James, ... Journal of medicinal chemistry 53 (18), 6640-6652, 2010 | 82 | 2010 |
Stereoselective synthesis of pyrrolidines: catalytic oxidative cyclizations mediated by osmium TJ Donohoe, GH Churchill, PA Glossop Angewandte Chemie 118 (47), 8193-8196, 2006 | 59 | 2006 |
The discovery of long acting β< sub> 2</sub>-adrenoreceptor agonists AD Brown, ME Bunnage, PA Glossop, K James, R Jones, CAL Lane, ... Bioorganic & medicinal chemistry letters 17 (14), 4012-4015, 2007 | 51 | 2007 |
Pyridine‐N‐Oxide as a Mild Reoxidant Which Transforms Osmium‐Catalyzed Oxidative Cyclization TJ Donohoe, PJ Lindsay‐Scott, PA Glossop, IA Nash, JS Parker Angewandte Chemie 120 (15), 2914-2917, 2008 | 46 | 2008 |
Inhalation by design: novel tertiary amine muscarinic m3 receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive … PA Glossop, CAL Watson, DA Price, ME Bunnage, DS Middleton, A Wood, ... Journal of medicinal chemistry 54 (19), 6888-6904, 2011 | 37 | 2011 |
The discovery of adamantyl-derived, inhaled, long acting β< sub> 2</sub>-adrenoreceptor agonists AD Brown, ME Bunnage, PA Glossop, K James, R Jones, CAL Lane, ... Bioorganic & medicinal chemistry letters 18 (4), 1280-1283, 2008 | 37 | 2008 |
The discovery of indole-derived long acting β< sub> 2</sub>-adrenoceptor agonists for the treatment of asthma and COPD AD Brown, ME Bunnage, PA Glossop, M Holbrook, RD Jones, CAL Lane, ... Bioorganic & medicinal chemistry letters 17 (22), 6188-6191, 2007 | 31 | 2007 |
Design and synthesis of long acting inhaled corticosteroids for the treatment of asthma DS Millan, SA Ballard, S Chunn, JA Dybowski, CK Fulton, PA Glossop, ... Bioorganic & medicinal chemistry letters 21 (19), 5826-5830, 2011 | 26 | 2011 |
Progress in the Development of Inhaled, Long-Acting b2-Adrenoceptor Agonists PA Glossop, DA Price Annual Reports in Medicinal Chemistry 41, 237, 2006 | 22 | 2006 |
Studies on DMDO-mediated benzylidene acetal oxidation DK Mycock, AE Sherlock, PA Glossop, CJ Hayes Tetrahedron Letters 49 (45), 6390-6392, 2008 | 21 | 2008 |
Identification of Type‐II Inhibitors Using Kinase Structures F Lovering, J McDonald, GA Whitlock, PA Glossop, C Phillips, A Bent, ... Chemical Biology & Drug Design 80 (5), 657-664, 2012 | 20 | 2012 |
Development of a Scaleable Synthesis of a Geminal Dimethyl Tertiary Amine as an Inhaled Muscarinic Antagonist for the Treatment of COPD BR Dillon, DF Roberts, DA Entwistle, PA Glossop, CJ Knight, DA Laity, ... Organic Process Research & Development 16 (2), 195-203, 2012 | 19 | 2012 |
Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure–activity relationships of substituted (1< i> S</i>, 4< i> S</i>)-4-(3, 4-dichlorophenyl)-< i … DS Middleton, M Andrews, P Glossop, G Gymer, A Jessiman, PS Johnson, ... Bioorganic & medicinal chemistry letters 16 (5), 1434-1439, 2006 | 18 | 2006 |
Efficient Conversion of a Nonselective Norepinephrin Reuptake Inhibitor into a Dual Muscarinic Antagonist− β2-Agonist for the Treatment of Chronic Obstructive Pulmonary Disease R Osborne, N Clarke, P Glossop, A Kenyon, H Liu, S Patel, S Summerhill, ... Journal of medicinal chemistry 54 (19), 6998-7002, 2011 | 17 | 2011 |
Osmium‐Mediated Oxidative Cyclizations: A Study into the Range of Initiators That Facilitate Cyclization TJ Donohoe, PJ Lindsay‐Scott, GH Churchill, MJ Connolly, S Butterworth, ... Chemistry–An Asian Journal 4 (8), 1237-1247, 2009 | 17 | 2009 |
NICOTINAMIDE DERIVATIVES JM Crawforth, PA Glossop, BC Hamper, W Huang, SJ Mantell, BE Neal, ... EP Patent 2,307,378, 2011 | 14 | 2011 |
NICOTINAMIDE DERIVATIVES JM CRAWFORTH, PA GLOSSOP, BC HAMPER, W HUANG, ... WO Patent 2,009,153,721, 2009 | 14 | 2009 |
Nicotinamide Derivatives JM Crawforth, PA Glossop, BC Hamper, W Huang, BE Neal, SJ Mantell, ... US Patent App. 12/997,987, 2009 | 14 | 2009 |
Designing rapid onset selective serotonin re-uptake inhibitors. Part 3: site-directed metabolism as a strategy to avoid active circulating metabolites: Structure–activity … DS Middleton, M Andrews, P Glossop, G Gymer, D Hepworth, A Jessiman, ... Bioorganic & medicinal chemistry letters 18 (19), 5303-5306, 2008 | 13 | 2008 |