Rho GTPases: masters of cell migration A Sadok, CJ Marshall Small GTPases 5 (4), e983878, 2014 | 256 | 2014 |
A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes Z Yin, A Sadok, H Sailem, A McCarthy, X Xia, F Li, MA Garcia, L Evans, ... Nature cell biology 15 (7), 860-871, 2013 | 197 | 2013 |
Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis S Kümper, FK Mardakheh, A McCarthy, M Yeo, GW Stamp, A Paul, ... elife 5, e12203, 2016 | 160 | 2016 |
An ezrin-rich, rigid uropod-like structure directs movement of amoeboid blebbing cells A Lorentzen, J Bamber, A Sadok, I Elson-Schwab, CJ Marshall Journal of cell science 124 (8), 1256-1267, 2011 | 155 | 2011 |
Rho kinase inhibitors block melanoma cell migration and inhibit metastasis A Sadok, A McCarthy, J Caldwell, I Collins, MD Garrett, M Yeo, S Hooper, ... Cancer research 75 (11), 2272-2284, 2015 | 146 | 2015 |
A strategy for high-level expression of soluble and functional human interferon α as a GST-fusion protein in E.coli I Rabhi-Essafi, A Sadok, N Khalaf, DM Fathallah Protein Engineering, Design & Selection 20 (5), 201-209, 2007 | 133 | 2007 |
Global analysis of mRNA, translation, and protein localization: local translation is a key regulator of cell protrusions FK Mardakheh, A Paul, S Kümper, A Sadok, H Paterson, A Mccarthy, ... Developmental cell 35 (3), 344-357, 2015 | 118 | 2015 |
Nox1-dependent superoxide production controls colon adenocarcinoma cell migration A Sadok, V Bourgarel-Rey, F Gattacceca, C Penel, M Lehmann, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1783 (1), 23-33, 2008 | 116 | 2008 |
Modulation of cellular redox state underlies antagonism between oxaliplatin and cetuximab in human colorectal cancer cell lines L Dahan, A Sadok, JL Formento, JF Seitz, H Kovacic British journal of pharmacology 158 (2), 610-620, 2009 | 113 | 2009 |
Myosin II reactivation and cytoskeletal remodeling as a hallmark and a vulnerability in melanoma therapy resistance JL Orgaz, E Crosas-Molist, A Sadok, A Perdrix-Rosell, O Maiques, ... Cancer Cell 37 (1), 85-103. e9, 2020 | 110 | 2020 |
Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation LA Pescatore, D Bonatto, FL Forti, A Sadok, H Kovacic, FRM Laurindo Journal of Biological Chemistry 287 (35), 29290-29300, 2012 | 89 | 2012 |
Nox1 downstream of 12‐lipoxygenase controls cell proliferation but not cell spreading of colon cancer cells DD de Carvalho, A Sadok, V Bourgarel‐Rey, F Gattacceca, C Penel, ... International journal of cancer 122 (8), 1757-1764, 2008 | 66 | 2008 |
A critical evaluation of the approaches to targeted protein degradation for drug discovery R Chopra, A Sadok, I Collins Drug Discovery Today: Technologies 31, 5-13, 2019 | 51 | 2019 |
NADPH oxidase 1 controls the persistence of directed cell migration by a Rho-dependent switch of α2/α3 integrins A Sadok, A Pierres, L Dahan, C Prévôt, M Lehmann, H Kovacic Molecular and cellular biology 29 (14), 3915-3928, 2009 | 42 | 2009 |
Rapid patterning of 1-D collagenous topography as an ECM protein fibril platform for image cytometry N Xue, X Li, C Bertulli, Z Li, A Patharagulpong, A Sadok, YYS Huang PLoS One 9 (4), e93590, 2014 | 34 | 2014 |
Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells S Cooper, A Sadok, V Bousgouni, C Bakal Molecular biology of the cell 26 (22), 4163-4170, 2015 | 32 | 2015 |
Dynamics of filopodium-like protrusion and endothelial cellular motility on one-dimensional extracellular matrix fibrils N Xue, C Bertulli, A Sadok, YYS Huang Interface Focus 4 (2), 20130060, 2014 | 17 | 2014 |
Rho GTPases: masters of cell migration. Small GTPases 2014; 5: e29710; PMID: 24978113 A Sadok, CJ Marshall | 6 | |
A Degron Blocking Strategy Towards Improved CRL4CRBN Recruiting PROTAC Selectivity** H Bouguenina, A Scarpino, JA O'Hanlon, J Warne, HZ Wang, ... ChemBioChem 24 (23), e202300351, 2023 | 3 | 2023 |
Abstract LBA004: Identification of GSPT1-directed molecular glue degrader (MGD) for the treatment of Myc-driven breast cancer G Gavory, B Fasching, D Bonenfant, A Sadok, A Singh, M Schillo, ... Molecular Cancer Therapeutics 20 (12_Supplement), LBA004-LBA004, 2021 | 3 | 2021 |