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Georgia Isom
Georgia Isom
Verified email at path.ox.ac.uk - Homepage
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Year
Architectures of lipid transport systems for the bacterial outer membrane
DC Ekiert, G Bhabha, GL Isom, G Greenan, S Ovchinnikov, IR Henderson, ...
Cell 169 (2), 273-285. e17, 2017
2252017
Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system
GW Hughes, SCL Hall, CS Laxton, P Sridhar, AH Mahadi, C Hatton, ...
Nature microbiology 4 (10), 1692-1705, 2019
1172019
MCE domain proteins: conserved inner membrane lipid-binding proteins required for outer membrane homeostasis
GL Isom, NJ Davies, ZS Chong, JA Bryant, M Jamshad, M Sharif, ...
Scientific reports 7 (1), 8608, 2017
672017
LetB structure reveals a tunnel for lipid transport across the bacterial envelope
GL Isom, N Coudray, MR MacRae, CT McManus, DC Ekiert, G Bhabha
Cell 181 (3), 653-664. e19, 2020
582020
Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
N Coudray, GL Isom, MR MacRae, MN Saiduddin, G Bhabha, DC Ekiert
Elife 9, e62518, 2020
492020
Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation
LR Kolich, YT Chang, N Coudray, SI Giacometti, MR MacRae, GL Isom, ...
Elife 9, e60030, 2020
362020
Loss of YhcB results in dysregulation of coordinated peptidoglycan, LPS and phospholipid synthesis during Escherichia coli cell growth
ECA Goodall, GL Isom, JL Rooke, K Pullela, C Icke, Z Yang, G Boelter, ...
PLoS genetics 17 (12), e1009586, 2021
232021
YraP contributes to cell envelope integrity and virulence of Salmonella enterica serovar Typhimurium
FC Morris, TJ Wells, JA Bryant, AE Schager, YR Sevastsyanovich, ...
Infection and immunity 86 (11), 10.1128/iai. 00829-17, 2018
132018
Evidence for phospholipid export from the bacterial inner membrane by the Mla ABC transport system. Nat Microbiol 4: 1692–1705
GW Hughes, SCL Hall, CS Laxton, P Sridhar, AH Mahadi, C Hatton, ...
82019
Phospholipid transport to the bacterial outer membrane through an envelope-spanning bridge
BF Cooper, R Clark, A Kudhail, G Bhabha, DC Ekiert, S Khalid, GL Isom
bioRxiv, 2023
52023
Structure of MlaFEDB lipid transporter reveals an ABC exporter fold and two bound phospholipids
N Coudray, GL Isom, MR MacRae, MN Saiduddin, G Bhabha, DC Ekiert
BioRxiv, 2020.06. 02.129247, 2020
52020
Mammalian Cell Entry domains are required for bile resistance and virulence in Salmonella
GL Isom, JL Rooke, CA Antunes, E Sheehan, TJ Wells, C Icke, ...
BioRxiv, 263871, 2018
42018
Role of Ring6 in the function of the E. coli MCE protein LetB
C Vieni, N Coudray, GL Isom, G Bhabha, DC Ekiert
Journal of molecular biology 434 (7), 167463, 2022
32022
Complete Closed Genome Sequence of Nontoxigenic Invasive Corynebacterium diphtheriae bv. mitis Strain ISS 3319
C Azevedo Antunes, EJ Richardson, J Quick, P Fuentes-Utrilla, GL Isom, ...
Genome Announcements 6 (5), 10.1128/genomea. 01566-17, 2018
32018
YhcB coordinates peptidoglycan and LPS biogenesis with phospholipid synthesis during Escherichia coli cell growth
ECA Goodall, GL Isom, JL Rooke, C Icke, K Pullela, B Zhang, J Rae, ...
bioRxiv, 2021.04. 16.440158, 2021
12021
Evidence for phospholipid export from the gram-negative inner membrane: time to rethink the Mla pathway?
GW Hughes, SCL Hall, CS Laxton, P Sridhar, AH Mahadi, C Hatton, ...
BioRxiv, 388546, 2018
12018
A role for proteobacterial mammalian cell entry domains in phospholipid trafficking and infection
GL Isom
University of Birmingham, 2017
12017
SARS-CoV-2 infection predisposes patients to coinfection with Staphylococcus aureus
A Lubkin, L Bernard-Raichon, AL DuMont, AM Valero Jimenez, GG Putzel, ...
Mbio 15 (8), e01667-24, 2024
2024
User experience: Using national Cryo EM centers towards studying lipid transport across the bacterial cell envelope
G Bhabha, D Ekiert, N Coudray, G Isom, M MacRae, R Redler
Microscopy and Microanalysis 27 (S1), 1422-1422, 2021
2021
Structure of the Bacterial Lipid ABC Transporter MlaFEDB Reveals Substrate Bound
MR MacRae, N Coudray, GL Isom, MN Saiduddin, G Bhabha, DC Ekiert
Biophysical Journal 120 (3), 212a, 2021
2021
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