Focal adhesion signaling and therapy resistance in cancer I Eke, N Cordes Seminars in cancer biology 31, 65-75, 2015 | 344 | 2015 |
β1 Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapy I Eke, Y Deuse, S Hehlgans, K Gurtner, M Krause, M Baumann, ... The Journal of clinical investigation 122 (4), 1529-1540, 2012 | 235 | 2012 |
Three-dimensional cell growth confers radioresistance by chromatin density modification K Storch, I Eke, K Borgmann, M Krause, C Richter, K Becker, E Schröck, ... Cancer research 70 (10), 3925-3934, 2010 | 224 | 2010 |
Radiobiology goes 3D: how ECM and cell morphology impact on cell survival after irradiation I Eke, N Cordes Radiotherapy and Oncology 99 (3), 271-278, 2011 | 151 | 2011 |
Caveolin-1 mediated radioresistance of 3D grown pancreatic cancer cells S Hehlgans, I Eke, K Storch, M Haase, GB Baretton, N Cordes Radiotherapy and Oncology 92 (3), 362-370, 2009 | 113 | 2009 |
The future of radiobiology DG Kirsch, M Diehn, AH Kesarwala, A Maity, MA Morgan, JK Schwarz, ... JNCI: Journal of the National Cancer Institute 110 (4), 329-340, 2018 | 111 | 2018 |
PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1α I Eke, U Koch, S Hehlgans, V Sandfort, F Stanchi, D Zips, M Baumann, ... The Journal of clinical investigation 120 (7), 2516-2527, 2010 | 110 | 2010 |
Simultaneous β1 integrin-EGFR targeting and radiosensitization of human head and neck cancer I Eke, K Zscheppang, E Dickreuter, L Hickmann, E Mazzeo, K Unger, ... Journal of the National Cancer Institute 107 (2), dju419, 2015 | 93 | 2015 |
EGFR/JIP-4/JNK2 signaling attenuates cetuximab-mediated radiosensitization of squamous cell carcinoma cells I Eke, L Schneider, C Förster, D Zips, LA Kunz-Schughart, N Cordes Cancer research 73 (1), 297-306, 2013 | 93 | 2013 |
3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226 S Hehlgans, I Lange, I Eke, N Cordes Radiotherapy and oncology 92 (3), 371-378, 2009 | 91 | 2009 |
Radiation-induced fibrosis: mechanisms and opportunities to mitigate. Report of an NCI workshop, September 19, 2016. DE Citrin, PGS Prasanna, AJ Walker, ML Freeman, I Eke, ... Radiation research 188 (1), 1-20, 2017 | 86 | 2017 |
Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells E Dickreuter, I Eke, M Krause, K Borgmann, MA Van Vugt, N Cordes Oncogene 35 (11), 1353-1362, 2016 | 83 | 2016 |
The small molecule inhibitor QLT0267 Radiosensitizes squamous cell carcinoma cells of the head and neck I Eke, F Leonhardt, K Storch, S Hehlgans, N Cordes PLoS One 4 (7), e6434, 2009 | 69 | 2009 |
Cetuximab attenuates its cytotoxic and radiosensitizing potential by inducing fibronectin biosynthesis I Eke, K Storch, M Krause, N Cordes Cancer research 73 (19), 5869-5879, 2013 | 64 | 2013 |
LIM-only protein FHL2 critically determines survival and radioresistance of pancreatic cancer cells E Zienert, I Eke, D Aust, N Cordes Cancer letters 364 (1), 17-24, 2015 | 61 | 2015 |
3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation I Eke, S Hehlgans, V Sandfort, N Cordes International journal of oncology 48 (1), 313-321, 2015 | 58 | 2015 |
Three-dimensional invasion of human glioblastoma cells remains unchanged by X-ray and carbon ion irradiation in vitro I Eke, K Storch, I Kästner, A Vehlow, C Faethe, W Mueller-Klieser, ... International Journal of Radiation Oncology* Biology* Physics 84 (4), e515-e523, 2012 | 57 | 2012 |
Targeting FAK radiosensitizes 3-dimensional grown human HNSCC cells through reduced Akt1 and MEK1/2 signaling S Hehlgans, I Eke, N Cordes International Journal of Radiation Oncology* Biology* Physics 83 (5), e669-e676, 2012 | 56 | 2012 |
Dual targeting of EGFR and focal adhesion kinase in 3D grown HNSCC cell cultures I Eke, N Cordes Radiotherapy and Oncology 99 (3), 279-286, 2011 | 56 | 2011 |
Radiation-induced long noncoding RNAs in a mouse model after whole-body irradiation MJ Aryankalayil, S Chopra, J Levin, I Eke, A Makinde, S Das, ... Radiation research 189 (3), 251-263, 2018 | 53 | 2018 |