Laura Gathercole
Laura Gathercole
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Glucagon-like peptide 1 decreases lipotoxicity in non-alcoholic steatohepatitis
MJ Armstrong, D Hull, K Guo, D Barton, JM Hazlehurst, LL Gathercole, ...
Journal of hepatology 64 (2), 399-408, 2016
11β-HSD1 is the major regulator of the tissue-specific effects of circulating glucocorticoid excess
SA Morgan, EL McCabe, LL Gathercole, ZK Hassan-Smith, DP Larner, ...
Proceedings of the National Academy of Sciences 111 (24), E2482-E2491, 2014
11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid-induced insulin resistance in skeletal muscle
SA Morgan, M Sherlock, LL Gathercole, GG Lavery, C Lenaghan, ...
Diabetes 58 (11), 2506-2515, 2009
11β-Hydroxysteroid dehydrogenase 1: translational and therapeutic aspects
LL Gathercole, GG Lavery, SA Morgan, MS Cooper, AJ Sinclair, ...
Endocrine reviews 34 (4), 525-555, 2013
Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue
LL Gathercole, SA Morgan, IJ Bujalska, D Hauton, PM Stewart, ...
PloS one 6 (10), e26223, 2011
A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis
IJ Bujalska, LL Gathercole, JW Tomlinson, C Darimont, J Ermolieff, ...
The Journal of endocrinology 197 (2), 297, 2008
Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes
LL Gathercole, PM Stewart
The Journal of steroid biochemistry and molecular biology 122 (1-3), 21-27, 2010
Glucocorticoid modulation of insulin signaling in human subcutaneous adipose tissue
LL Gathercole, IJ Bujalska, PM Stewart, JW Tomlinson
The Journal of Clinical Endocrinology & Metabolism 92 (11), 4332-4339, 2007
Lack of significant metabolic abnormalities in mice with liver-specific disruption of 11β-hydroxysteroid dehydrogenase type 1
GG Lavery, AE Zielinska, LL Gathercole, B Hughes, N Semjonous, ...
Endocrinology 153 (7), 3236-3248, 2012
Glucocorticoids fail to cause insulin resistance in human subcutaneous adipose tissue in vivo
JM Hazlehurst, LL Gathercole, M Nasiri, MJ Armstrong, S Borrows, J Yu, ...
The Journal of Clinical Endocrinology & Metabolism 98 (4), 1631-1640, 2013
Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake
JC McNelis, KN Manolopoulos, LL Gathercole, IJ Bujalska, PM Stewart, ...
American Journal of Physiology-Endocrinology and Metabolism 305 (9), E1134-E1144, 2013
Adipocyte differentiation, mitochondrial gene expression and fat distribution: differences between zidovudine and tenofovir after 6 months
M Boothby, KC McGee, JW Tomlinson, LL Gathercole, PG McTernan, ...
Antivir Ther 14 (8), 1089-100, 2009
Regulation of lipid metabolism by glucocorticoids and 11β-HSD1 in skeletal muscle
SA Morgan, LL Gathercole, C Simonet, ZK Hassan-Smith, I Bujalska, ...
Endocrinology 154 (7), 2374-2384, 2013
Sequence variation of intergenic mitochondrial DNA spacers (mtDNA‐IGS) of Phytophthora infestans (Oomycetes) and related species
RAM Wattier, LL Gathercole, SJ Assinder, CJ Gliddon, KL Deahl, ...
Molecular Ecology Notes 3 (1), 136-138, 2003
Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome
M O'Reilly, L Gathercole, F Capper, W Arlt, J Tomlinson
The Lancet 385, S16, 2015
The Role of 11-Hydroxysteroid Dehydrogenase 1 in Adipogenesis in Thyroid-Associated Ophthalmopathy
JW Tomlinson, OM Durrani, IJ Bujalska, LL Gathercole, PJ Tomlins, ...
The Journal of Clinical Endocrinology & Metabolism 95 (1), 398-406, 2010
5α-reductase type 2 regulates glucocorticoid action and metabolic phenotype in human hepatocytes
M Nasiri, N Nikolaou, S Parajes, NP Krone, G Valsamakis, G Mastorakos, ...
Endocrinology 156 (8), 2863-2871, 2015
Tissue specific regulation of glucocorticoids in severe obesity and the response to significant weight loss following bariatric surgery (BARICORT)
CP Woods, M Corrigan, L Gathercole, A Taylor, B Hughes, G Gaoatswe, ...
The Journal of Clinical Endocrinology & Metabolism 100 (4), 1434-1444, 2015
Hormonal regulation of lipogenesis
LL Gathercole, SA Morgan, JW Tomlinson
Vitamins & Hormones 91, 1-27, 2013
Short-and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue
LL Gathercole, SA Morgan, IJ Bujalska, PM Stewart, JW Tomlinson
Nutrition & Diabetes 1 (1), e3-e3, 2011
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