A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1199 | 2016 |
Widespread expansion of protein interaction capabilities by alternative splicing X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ... Cell 164 (4), 805-817, 2016 | 545 | 2016 |
Systematic analysis of complex genetic interactions E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ... Science 360 (6386), eaao1729, 2018 | 265 | 2018 |
SiteFinding-PCR: a simple and efficient PCR method for chromosome walking G Tan, Y Gao, M Shi, X Zhang, S He, Z Chen, C An Nucleic acids research 33 (13), e122-e122, 2005 | 185 | 2005 |
A framework for exhaustively mapping functional missense variants J Weile, S Sun, AG Cote, J Knapp, M Verby, JC Mellor, Y Wu, C Pons, ... Molecular systems biology 13 (12), 957, 2017 | 168 | 2017 |
T‐linker‐specific ligation PCR (T‐linker PCR): an advanced PCR technique for chromosome walking or for isolation of tagged DNA ends Y Yuanxin, A Chengcai, L Li, G Jiayu, T Guihong, C Zhangliang Nucleic acids research 31 (12), e68-e68, 2003 | 151 | 2003 |
An extended set of yeast-based functional assays accurately identifies human disease mutations S Sun, F Yang, G Tan, M Costanzo, R Oughtred, J Hirschman, ... Genome research 26 (5), 670-680, 2016 | 142 | 2016 |
Temperature-sensitive mutations made easy: generating conditional mutations by using temperature-sensitive inteins that function within different temperature ranges G Tan, M Chen, C Foote, C Tan Genetics 183 (1), 13-22, 2009 | 62 | 2009 |
A global genetic interaction network maps a wiring diagram of cellular function. Science 353: aaf1420 M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... | 57 | 2016 |
Complex modifier landscape underlying genetic background effects J Hou, G Tan, GR Fink, BJ Andrews, C Boone Proceedings of the National Academy of Sciences 116 (11), 5045-5054, 2019 | 49 | 2019 |
Rapid and efficient plasmid construction by homologous recombination in yeast J van Leeuwen, B Andrews, C Boone, G Tan Cold Spring Harbor Protocols 2015 (9), pdb. prot085100, 2015 | 45 | 2015 |
Systematic analysis of bypass suppression of essential genes J Van Leeuwen, C Pons, G Tan, JZ Wang, J Hou, J Weile, M Gebbia, ... Molecular systems biology 16 (9), e9828, 2020 | 41 | 2020 |
Identifying pathogenicity of human variants via paralog-based yeast complementation F Yang, S Sun, G Tan, M Costanzo, DE Hill, M Vidal, BJ Andrews, ... PLoS genetics 13 (5), e1006779, 2017 | 37 | 2017 |
Identification of a bHLH-type G-box binding factor and its regulation activity with G-box and Box I elements of the PsCHS1 promoter W Qian, G Tan, H Liu, S He, Y Gao, C An Plant cell reports 26, 85-93, 2007 | 37 | 2007 |
Leveraging DNA damage response signaling to identify yeast genes controlling genome stability JA Hendry, G Tan, J Ou, C Boone, GW Brown G3: Genes, Genomes, Genetics 5 (5), 997-1006, 2015 | 31 | 2015 |
The LSD1-interacting protein GILP is a LITAF domain protein that negatively regulates hypersensitive cell death in Arabidopsis S He, G Tan, Q Liu, K Huang, J Ren, X Zhang, X Yu, P Huang, C An PLoS One 6 (4), e18750, 2011 | 29 | 2011 |
The proteomic landscape of genome-wide genetic perturbations CB Messner, V Demichev, J Muenzner, SK Aulakh, N Barthel, A Röhl, ... Cell 186 (9), 2018-2034. e21, 2023 | 24 | 2023 |
Construction of multifragment plasmids by homologous recombination in yeast J van Leeuwen, B Andrews, C Boone, G Tan Cold Spring Harbor Protocols 2015 (9), pdb. top084111, 2015 | 10 | 2015 |
Expanding the atlas of functional missense variation for human genes J Weile, S Sun, AG Cote, J Knapp, M Verby, J Mellor, Y Wu, C Pons, ... bioRxiv, 166595, 2017 | 5 | 2017 |
SMC, a simple method to rapidly assemble multiple fragments into one construct G Tan, C Tan Front Biosci (Elite Ed) 2, 1105-1114, 2010 | 4 | 2010 |